Clinical trials: Magnetic Resonance Imaging (MRI)
Low Back Pain
Modic Changes and Associated Features in Southern European Chronic Low Back Pain Patients
To assess: a) The prevalence of Modic changes and other findings on lumbar magnetic resonance imaging (MRI), among Spanish adult chronic LBP patients, b) Patient characteristics and radiological findings associated with Modic…
- Trial name
- MODIC (NCT00478868)
- Where
- Spain
- Volunteers
- 487 people
- Sponsor
- Kovacs Foundation
Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain
Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea
Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects.
- Conditions
- Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain, Functional Magnetic Resonance Imaging, IBS (Irritable Bowel Syndrome)
- Trial name
- NCT06757491
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Placenta Diseases
MARS: Magnetic Resonance Study: A Novel Assessment of Placental Function
The objective of this study is to evaluate functional MRI as a tool to study placental transfer of oxygen and nutrients during the third trimester of pregnancy in obese women, women with pregestational diabetes and healthy low…
- Trial name
- NCT03764878
- Testing
- functional MRI
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Endometrial Cancer, Endometrial Neoplasms
Can Staging Magnetic Resonance Imaging (MRI) Features Prognosticate Patients Presenting With Endometrial Cancer?
Aim: Assess the value of MRI features in predicting prognosis in patients with endometrial cancer This study will examine the MRI features of women with confirmed endometrial cancer to see if textural features can prognosticate…
- Trial name
- NCT03543215
- Testing
- Radiomics: Analysis of textural features of imaging (MRI and Ultrasound)
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Imperial College London
Healthy Volunteer
Brain Effect of Vagal Nerve Stimulation at Rest and Pain
Pain is a ubiquitous distressing sensory experience and is the most frequent symptom in numerous gastrointestinal disorders including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS).
- Trial name
- NCT04282226
- Testing
- active transcutaneous Vagal Nerve Stimulation (tVNS)
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Structure and Function of MRI
Ultrahigh Field Body MR Imaging
The primary objective of this study is to develop new ways to acquire MRI data and/or new ways to analyze the acquired data.
- Trial name
- NCT02236143
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiac Disease
Validation of Combined PET-MR Quantitative Parameters for Cardiac Applications
The purpose of this study is to understand how simultaneous PET/MR acquisition can provide novel qualitative and quantitative biomarkers to guide clinical intervention and predict prognosis of patients with cardiovascular disease.
- Trial name
- NCT02062008
- Testing
- PET-MRI
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Multiple Sclerosis
Sunphenon in Progressive Forms of Multiple Sclerosis
The investigators hypothesize that an oral Sunphenon EGCg (Epigallocatechin-Gallat, EGCG) treatment is - due to its antiinflamatoric and neuroprotective potence - significantly more effective than an oral placebo treatment…
- Trial name
- SUPREMES (NCT00799890)
- Testing
- Sunphenon EGCG
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- Friedemann Paul
Endolymphatic Hydrops
Comparison of 3 Methods to Diagnose Endolymphatic Hydrops in Meniere's Disease
The aim of this study is to compare 3 methods for the diagnosis of endolymphatic hydrops (EH) in patients with Meniere's disease: MRI 3 Tesla (to visualise EH directly), and functional explorations, namely electrocochleography…
- Trial name
- MRI Meniere (NCT03215420)
- Testing
- MRI 3T
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Breast Cancer
Quantitative MRI Assessment of Breast Cancer Therapy Response
The goal of this observational study is to investigate and validate multi-parametric magnetic resonance imaging (MRI) modalities for assessment of breast cancer response to neoadjuvant chemotherapy in a multi-site and multi-MRI…
- Trial name
- NCT05704062
- Testing
- Diffusion Weighted Imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging
- Where
- 4 sites in United States
- Volunteers
- 135 people
- Sponsor
- Corewell Health East
Multiple Sclerosis
Rebif Advanced Magnetic Resonance Imaging (MRI) and Immunology Pilot Trial
The purpose of this trial is to evaluate the effects of Rebif® 44 mcg subcutaneous (sc) three times a week (tiw) on a) remyelination/demyelination, b) lesion and brain volume, c) central nervous system (CNS) iron deposition, and…
- Trial name
- NCT01085318
- Testing
- Rebif
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- EMD Serono
Episodic Memory Retrieval
rTMS Brain Stimulation and Cognition
This study will use repetitive transcranial magnetic stimulation (rTMS) (a way to use a powerful magnet to cause temporary impairment to the function of a brain region) to test whether certain parts of the brain are necessary to…
- Trial name
- NCT04244682
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stephan Hamann
Alcohol Use Disorder
Involvement of the Septal Nuclei of the Human Brain in Alcohol Use Disorder
Alcohol activates reward systems in different brain areas, i.e., the nucleus accumbens, dorsal striatum, extended amygdala, and prefrontal cortex.
- Trial name
- NCT06866379
- Testing
- Brain imaging
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Takotsubo Cardiomyopathy, Machine Learning
Prognotic Role of CMR in Takotsubo Syndrome
The primary objective of this observational registry is to develop a comprehensive clinical and imaging score (incorporating echocardiography and cardiac magnetic resonance data) that enhances risk stratification for patients…
- Conditions
- Takotsubo Cardiomyopathy, Machine Learning, Magnetic Resonance Imaging
- Trial name
- EVOLUTION (NCT06277297)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- University of Cagliari
Breast Neoplasms
MRI and Early Decision-making in Chemotherapy for Breast Cancer
Firstly, the investigators aim to show that breast tumour blood flow, measured as part of a standard MRI examination, decreases at the earliest stage of neoadjuvant chemotherapy in those patients who go on to respond to…
- Trial name
- CHERNAC (NCT02449824)
- Testing
- magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Leeds
COVID-19, Virus Disease
Prevalence of Myocardial Scars on CMR After COVID-19 Infection
The aim of this study is to assess the prevalence and arrhythmogenic role of occult myocardial scars on Cardiac Magnetic Resonance (CMR) in a population of patients with history of laboratory-proven symptomatic COVID-19 infection…
- Trial name
- COVID-CMR (NCT04636320)
- Testing
- Contrast-enhanced CMR, Exercise test ECG, Blood sample
- Where
- France
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Conditions Requiring a Brain Magnetic Resonance Imaging, Head Computerized Tomography, or Head Ultrasound
Low Field and High Field Magnetic Resonance Imaging Assessments on Pediatric Patients
Hyperfine Research, Inc. has taken advantage of technological advances and developed an MRI device that is not only portable, but also uses a very-low magnetic field strength, [less than 0.2 Tesla or approximately 10 times less]…
- Trial name
- NCT04629469
- Testing
- Hyperfine MRI
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Children's Mercy Hospital Kansas City
Oral Cancer
Assessment of Mandibular Bone Invasion With MRI Using SWIFT
The primary objective of this study is to improve the diagnostic accuracy and specificity of MRI in detecting the degree of bone involvement and invasion in oral cancer.
- Trial name
- NCT01817140
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Minnesota
Insulin Resistance, Transcranial Direct Current Stimulation
Improving Insulin Sensitivity by Non-invasive Brain Stimulation
Efforts in curing and preventing obesity and type 2 diabetes (T2D) have been elusive thus far. One reason for that is the lack of understanding of the role of the brain in the development and treatment of the disease.
- Conditions
- Insulin Resistance, Transcranial Direct Current Stimulation, Obesity, Diabetes
- Trial name
- NCT04420650
- Testing
- transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Colorectal Cancer, Coffee
COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery…
- Conditions
- Colorectal Cancer, Coffee, Gastrointestinal Microbiome, Stenosis
- Trial name
- COMMENCER (NCT05692024)
- Testing
- Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
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