Clinical trials: Magnetic Resonance Imaging (MRI)
Sarcoma
Quantitative Imaging Biomarkers for Sarcoma
Unless a cancer quickly gets smaller with radiation or chemotherapy, the investigators cannot tell if the treatment is working or not.
- Trial name
- NCT02579980
- Testing
- DCE and DWI MRI, Surgery
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Columbia University
Stroke
Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke
WAKE-UP is an investigator initiated European multicenter randomized controlled clinical trial of MRI based thrombolysis in acute stroke patients with unknown time of symptom onset, e.g.
- Trial name
- WAKE-UP (NCT01525290)
- Testing
- Alteplase
- Where
- 7 sites in Belgium, Denmark and 4 more
- Volunteers
- 501 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
CAD
Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System
Background: Researchers are testing version of a system known as a magnetic resonance imagining (MRI) scanner that uses strong magnetic fields, radio waves and the like to create images of the organs in the body.
- Trial name
- NCT03331380
- Testing
- MRI scan - obj 1, MRI scans - obj 2, MRI scans - obj 3
- Where
- United States
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Lung Transplant Rejection
HP 129Xe MRI for Evaluation of CLAD in Lung Transplant Recipients
To evaluate the feasibility of hyperpolarized 129Xe MRI in lung transplant recipients and assess structural and functional pulmonary changes using hyperpolarized 129Xe MRI
- Trial name
- NCT05550662
- Testing
- 129Xenon
- Where
- 2 sites in Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cocaine Dependence, Opioid Dependence
FMRI of Stress and Addictive Disorders
The purpose of this study is to explore whether frontal brain activation in response to stress varies as a function of the presence or extent of early trauma and whether or not this effect is greater in women compared to men.
- Conditions
- Cocaine Dependence, Opioid Dependence, Alcoholism, Pathological Gamblers
- Trial name
- NCT01558973
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Conditions Influencing Health Status, Bipolar Disorders
Functional Correlates of Bipolar Disorders and Effects of the Psychoeducation. an fMRI Study
This research project follows two main objectives: 1) Assess anatomical and functional cerebral abnormalities in bipolar disorder.
- Trial name
- BIP-ED (NCT01821469)
- Testing
- psychoeducation
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Congenital Heart Disease
Imaging by 4 DFlow in Patients With Tetralogy of Fallot
Conventionnal cadiac magnetic resonance (CMR) is the reference to assess changes in right heart flow and pulmonary artery hemodynamics in patients with repaired Tetralogy of Fallot.
- Trial name
- 4DFlowFallot (NCT03542968)
- Testing
- magnetic resonance imaging
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Sleep Deprivation, Hippocampal Atrophy
Chronic Sleep Deprivation and Changes in Cortical and Hippocampal Volume
Sleep is a physiological state that is essential for human performance, including academic, occupational, interpersonal, and psychological aspects.
- Conditions
- Sleep Deprivation, Hippocampal Atrophy, Cortical Irregularity
- Trial name
- NCT06260280
- Testing
- Cerebral Nuclear Magnetic Resonance
- Where
- Mexico
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Amphetamine Use Disorders
Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder
Methamphetamine use disorder (MUD) is among the costliest and deadliest substance use disorders (SUDs) world-wide and is frequently comorbid with other mental health conditions.
- Trial name
- NeuroMethDC (NCT03382379)
- Testing
- Active transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Transcranial Electrical Stimulation, Temporal Lobe Epilepsy
Transcranial Electrical Stimulation Targeting the Cerebellum for the Treatment of Refractory Temporal Lobe Epilepsy
Study the therapeutic effect and potential neural mechanisms of transcranial electrical stimulation targeting the cerebellum for the treatment of refractory temporal lobe epilepsy through MRI and EEG.
- Conditions
- Transcranial Electrical Stimulation, Temporal Lobe Epilepsy, Magnetic Resonance Imaging, Electroencephalogram
- Trial name
- NCT06558890
- Testing
- Transcranial Alternating Current Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
PTSD
Precise Transcranial Magnetic Stimulation for Post-traumatic Stress Disorder
The purpose of this study is to investigate the efficacy and safety of repetitive transcranial magnetic stimulation under precise localization for post-traumatic stress disorder
- Trial name
- NCT05544110
- Testing
- Active transcranial magnetic stimulation
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Xijing Hospital
Headache, Migraine
The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA) on Healthy Volunteers
Studying Pituitary adenylate cyclase-activating peptide 27 (PACAP27) effects on extra- and intracerebral arteries assessed by MRA on healthy volunteers.
- Trial name
- NCT03560024
- Testing
- PACAP27
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Heart Transplant Failure and Rejection, Magnetic Resonance Imaging
Heart TIMING - Heart Transplantation IMagING
The cardiac allograft rejection (CAR) and cardiac allograft vasculopathy (CAV) significantly affect the prognosis of patients after heart transplantation.
- Trial name
- NCT03499197
- Testing
- cardiac magnetic resonance imaging
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Low Back Pain
Comparison of the Stiffness of the Lumbar Back Muscles Between Low Back Pain and Healthy Controls
Chronic low back pain remains a major public health issue. Low back pain is frequently associated with stiffness changes of the lumbar back muscles.
- Trial name
- PARA-ELASTO (NCT03750474)
- Testing
- magnetic resonance elastography and shear wave elastography
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Hypertension
Novel Quantitative Magnetic Resonance Imaging (MRI) Measures in the Assessment and Follow-up of Patients With Pulmonary Hypertension (PH)
A prospective study of the use of two novel MRI techniques (oxygen-enhanced and fourier decomposition MRI) in the initial diagnosis and follow-up of patients with Pulmonary Hypertension.
- Trial name
- NCT04088279
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Supraspinatus Injury
Added Value of Sonoelastography in Assessment of Traumatic and Non Traumatic Supraspinatus Tendinopathy and Tear Compared with Magnetic Resonance Imaging
Primary Aims: To assess the value of sonoelastography in the evaluation of supraspinatus tendon abnormalities. Secondary Aims: 1.
- Trial name
- NCT06803303
- Testing
- sonoelastography
- Volunteers
- 43 people
- Sponsor
- Assiut University
Transcranial Direct Current Stimulation, Post-Concussion Syndrome
Effects of tDCS for Enhancing Cognitive Function in Individuals With Persistent Post-Concussion Syndrome
Globally, 10 million new traumatic brain injury (TBI) cases are estimated annually, with mild traumatic brain injury (mTBI) accounting for 75-90% of all TBI cases.
- Conditions
- Transcranial Direct Current Stimulation, Post-Concussion Syndrome, Functional Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy
- Trial name
- NCT06376500
- Testing
- tDCS with cognitive training programme
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Ischemic Stroke, Atherosclerosis
Preventive Effects of Ginseng Against Atherosclerosis
This study is a 12-month, double-blind, randomized, placebo-controlled trial. The purpose of this study is to determine whether ginseng is effective in the prevention of atherosclerosis and subsequent ischemic stroke.
- Trial name
- PEGASUS (NCT02796664)
- Testing
- Ginseng
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Dae Chul Suh
Ocular Ischemia Syndrome
Early Diagnosis for Ocular Ischemia Syndrome Using Arterial Spin Labeling Magnetic Resonance Imaging Technique
1. To evaluate ocular blood perfusion status and the possibility of craniocerebral vascular lesions of patients with ocular ischemia syndrome (OIS) using arterial spin labeling (ASL) magnetic resonance imaging technique. 2.
- Trial name
- NCT03863171
- Testing
- Arterial spin labeling (ASL) magnetic resonance imaging, Fundus fluorescein angiography
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Beijing Friendship Hospital
Mental Health, Anxiety
Anxiety in Children and Families During MRI Under Anesthesia
This prospective randomized controlled study evaluates the impact of age-appropriate therapeutic play and structured parental briefing on perioperative anxiety during pediatric MRI under sedation.
- Trial name
- NCT07693309
- Testing
- Multi-modal Psychological Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Afyonkarahisar Health Sciences University
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