Clinical trials: Magnetic Resonance Imaging (MRI)
Posterior Cortical Atrophy
Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy
This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (PCA).
- Trial name
- PCA (NCT07191327)
- Testing
- HD-tDCS sessions, HD-tDCS sessions - Open-label (after randomized treatment)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Cirrhosis, Hepatocellular Carcinoma
Comparison of Biannual Ultrasonography and Annual Unenhanced Magnetic Resonance Imaging for HCC Surveillance
The purpose of this study is to investigate clinical feasibility of annual non-contrast magnetic resonance imaging for surveillance of hepatocellular carcinoma in high-risk group, in comparison with biannual ultrasonography.
- Trial name
- NCT02854241
- Testing
- Biannual ultrasonography, Annual noncontrast liver MRI, Contrast enhanced liver CT
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Hyperlipidemia
Comparison of LDL Particle Count With Other Available Lipid Tests
Despite the wide availability of advanced lipoprotein tests, no reference standard exists for Low Density Lipoprotein Cholesterol (LDL-C) due to inherent problems with each of the assays.
- Trial name
- LIPID (NCT02298894)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Scripps Clinic
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Schizophrenia, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Schizophrenia Patients With Auditory Hallucinations
To investigate the treatment effect of continuous transcranial magnetic stimulation on schizophrenia patients with auditory hallucinations, and the underlying neural mechanism by functional MRI
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging
- Trial name
- NCT02863094
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Rheumatoid Arthritis
Positron Emission Tomography and Magnetic Resonance Imaging to Evaluate Synovial Blood Flow in Rheumatoid Arthritis Patients
This study will test whether positron emission tomography (PET) imaging can be used to measure blood flow to joints in patients with rheumatoid arthritis (RA).
- Trial name
- NCT00014794
- Testing
- 15-O labeled water
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Lung Cancer, Surgery
CMR Right Ventricular Contractile Reserve Following Lung Resection
Feasibility study investigating CMR dobutamine stress testing before and after lung resection
- Conditions
- Lung Cancer, Surgery, Anesthesia
- Trial name
- NCT06465277
- Testing
- Dobutamine stress CMR, Cardiac biomarker sample
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Healthy
Refinement and Assessment of New Magnetic Resonance Imaging (MRI) Technologies for Vascular, Abdominal, and Pelvic Exams
This study is being done to assess new Magnetic Resonance Imaging (MRI) technologies designed to improve MRI examinations of the vascular structures, abdomen, and pelvis regions.
- Trial name
- NCT00738712
- Testing
- MRI Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Leukoaraiosis, Magnetic Resonance Imaging
Leucoaraiosis and Multimodal MRI With Fingerprinting Technique
Leukoaraiosis (LA) corresponds to an alteration of the encephalic white matter, linked to chronic hypoxia. Its pathophysiology, which has been partially elucidated, is underpinned by chronic changes in the walls of small-caliber…
- Trial name
- LEUKOPRINT (NCT06181981)
- Testing
- MRI fingerprinting
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Lille Catholic University
Chronic Ankle Instability, CAI, Functional Magnetic Resonance Imaging (fMRI)
fMRI Study on Cerebral Localization and Network Mechanisms of rTMS in Chronic Ankle Instability Treatment
Chronic ankle instability (CAI) is a common sports injury that often leads to recurrent injuries and functional deficits. While conventional rehabilitation can restore ankle stability, the underlying neurophysiological mechanisms…
- Trial name
- NCT06971705
- Testing
- repetitive transcranial magnetic stimulation, rTMS, ankle stability training
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Wuhan University
Nasopharyngeal Cancinoma (NPC), Distant Metastasis
Development and Validation of a Deep Learning Model to Predict Distant Metastases in Nasopharyngeal Carcinoma Using Whole Slide Imaging and MRI
An AI model was developed to predict the likelihood of distant metastasis in patients with nasopharyngeal cancer based on pathology slides and MRI scans of the primary tumor.
- Trial name
- NCT06831357
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Sun Yat-sen University
End Stage Kidney Disease, Fibrosis Myocardial
Validating Novel, Non-contrast Cardiac MRI Imaging in Haemodialysis Patients
There are currently no good ways of measuring levels of scarring in the hearts of patients with advanced kidney disease and patients on dialysis, although recent research has shown a new cardiac MRI technique, called native T1…
- Trial name
- CONFIRM (NCT03586518)
- Testing
- Cardiac MRI scan, Echocardiogram, Cardiac explantation
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Leicester
Overweight, Obesity
A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or without type 2 diabetes (T2D). The study will last about 56 weeks and include up to 12 visits.
- Conditions
- Overweight, Obesity, Chronic Kidney Disease, Type 2 Diabetes
- Trial name
- TREASURE-CKD (NCT05536804)
- Testing
- Tirzepatide
- Where
- 27 sites in United States, Austria and 4 more
- Volunteers
- 134 people
- Sponsor
- Eli Lilly and Company
Radiomics, Hepatocellular Carcinoma (HCC)
Microvascular Invasion for Guiding Treatment of Barcelona Clinic Liver Cancer Stage B Hepatocellular Carcinoma
The goal of this observational study is to explore the role of prediction of microvascular invasion by radiomics based on pre-treatment magnetic resonance imaging for guiding treatment of Barcelona Clinic Liver Cancer stage B…
- Conditions
- Radiomics, Hepatocellular Carcinoma (HCC), Transcatheter Arterial Chemoembolization (TACE), Microvascular Invasion (MVI)
- Trial name
- NCT05889949
- Testing
- Sorafenib, Lenvatinib
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Emotions
Questionnaire and Projective Color Association in Physiological Responses to Different Emotional Charge
A sample of 101 individuals will be used for this purpose, where each of them will be exposed to 145 different stimuli. Comparison of their physiological responses to stimuli (cerebral blood flow, electrical activity of the…
- Trial name
- PARC (NCT05363852)
- Testing
- Standard set of visual word and picture stimuli
- Where
- Czechia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Prostate Cancer
PRostate Evaluation for Clinically Important Disease: MRI vs Standard Evaluation Procedures
The aim of this study is to assess the efficacy of MRI-targeted biopsy compared to standard of care systematic TRUS guided biopsy in the detection of clinically significant and clinically insignificant prostate cancer in men…
- Trial name
- PRECISE (NCT02936258)
- Testing
- Standard of Care, MRI, MRI Targeted Biopsy
- Where
- 5 sites in Canada
- Volunteers
- 450 people
- Sponsor
- Canadian Urology Research Consortium
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response
Many patients with Major Depressive Disorder (MDD) and generalized Social Anxiety Disorder (gSAD) are treated with cognitive behavioral therapy (CBT) but few have meaningful improvement.
- Trial name
- NCT03175068
- Testing
- CBT, ST
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Adnexal Lesion
Role of Magnetic Resonance Imaging in Diagnosis of Adnexal Cystic Lesions
This prospective study aims to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in characterizing adnexal cystic lesions and differentiating benign from malignant lesions.
- Trial name
- NCT07334184
- Testing
- Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Obsessive-Compulsive Disorder
Effect of Cognitive Behavioral Therapy in OCD Highlighted by Neuropsychological Tests and MRI: Pathophysiology and Treatment Outcome Predictors
OCD patients are assessed before and after treatment using diagnostic tools, rating scales neuropsychological assessment and functional and structural MR-scans.
- Trial name
- NCT00792038
- Where
- Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Liver Cirrhosis
Annual MRI Versus Biannual US for Surveillance of Hepatocellular Carcinoma in Liver Cirrhosis
The investigators will investigate the usefulness of biannual ultrasonography versus annual non-contrast magnetic resonance imaging for surveillance of hepatocellular carcinoma in single arm patients.
- Trial name
- MAGNUS-HCC (NCT02551250)
- Testing
- annual noncontrast MRI, biannual ultrasonography
- Where
- 6 sites in South Korea
- Volunteers
- 211 people
- Sponsor
- JOON-IL CHOI
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