Clinical trials: Magnetic Resonance Imaging (MRI)
Transcranial Direct Current Stimulation, EEG
High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Refractory Epilepsy
To observe the clinical effect and safety of transcranial electrical stimulation on patients with refractory epilepsy before and after treatment and analyze its therapeutic mechanism.
- Conditions
- Transcranial Direct Current Stimulation, EEG, Functional Magnetic Resonance Imaging, Refractory Epilepsy
- Trial name
- NCT06241963
- Testing
- Active Comparator: Unilateral real High definition transcranial direct current stimulation, Active Comparator: Bilateral real High definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Moyamoya Disease, Magnetic Resonance Imaging
Predicative Value of Multimodal MRI in Moyamoya Disease
Moyamoya disease (MMD) is a nonatherosclerotic cerebrovascular abnormality, characterized by a progressive stenosis or occlusion of the intracranial internal carotid arteries (ICAs) and their proximal branches, with subsequent…
- Trial name
- NCT03785171
- Testing
- surgical revascularization
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Genu Varum, Football Players
The Influence of the Lower Limb Components on Genu Varum in Football Players
Objectives: To evaluate lower extremity alignments in football players with and without genu varum using magnetic resonance imaging (MRI), to determine the mechanisms underlying malalignment and the factors contributing to it.
- Trial name
- NCT06606964
- Testing
- Magnetic Resonance Imaging, Isokinetic Strength
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Sickle Cell Anemia
State Of The Art Functional Imaging In Sickle Cell Disease
Sickle cell anemia (SCA) is a serious blood disease with blood vessel changes leading to brain injury and stroke. Studies show about 11% of patients with SCA will develop obvious stroke before age 20 years, with children less…
- Trial name
- NCT01137721
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Pathological Gambling, Obsessive Compulsive Disorder
Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD)
This study will explore the brain processes associated with inhibition and reward processing in pathological gamblers and people with obsessive compulsive disorder compared to healthy controls.
- Trial name
- NCT00211822
- Testing
- fMRI
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Tachyarrhythmia
Magnetic Resonance (MR) Conditional Tachyarrhythmia Therapy Products Post-approval Study
Following product approval, further confirmation of the MR Conditional Tachyarrhythmia Therapy Systems sensing and detection performance post MRI exposure will be obtained by actively monitoring de-identified device data obtained…
- Trial name
- NCT02849769
- Testing
- Implant of an MR-conditional Tachy device system
- Volunteers
- 10,979 people
- Sponsor
- Medtronic
Schizophrenia
Modulation of Regional Brain Activation in Schizophrenic Patients by Pharmacological Therapy
The study aims to investigate the modulation of regional brain activation in schizophrenic patients by psychopharmacological treatment with either haloperidol, amisulpride or olanzapine.
- Trial name
- NCT00419653
- Testing
- Amisulpride, Olanzapine, Haloperidol
- Volunteers
- 19 people
- Sponsor
- University of Jena
Aphasia
The Usage of High-resolution Magnetic Resonance Imaging in Patients With Post-stroke Aphasia for Predicting the Outcome
Combined analysis of functional and structural language network changes may be a good model for predicting language outcome.
- Trial name
- NCT03475745
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Prostatic Neoplasms
Pre-operative PET-MR of High Risk Prostate Cancer Patients for Assessment of Cancer Aggressiveness and Lymph Node Status
Prostate cancer is the most frequent cancer in Norwegian men. For optimal treatment, accurate staging of the disease at the time point of diagnosis is important.
- Trial name
- NCT02076503
- Testing
- PET-MR 18f-FACBC, histology (gold standard)
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- St. Olavs Hospital
Neck Pain
Characteristics of Rheumatoid Arthritis Patients With Atlantoaxial Synovitis Detected by Plain X-ray and MRI
This study detects the presence of atlantoaxial joint affection in symptomatic versus asymptomatic rheumatoid arthritis patients revealed by plain X-ray and magnetic resonance imaging of the cervical spine
- Trial name
- MRI (NCT02774070)
- Testing
- Plain X-ray, Magnetic resonance imaging
- Sponsor
- Assiut University
Soft Tissue Neoplasms
Feasibility of ExAblate MRI Guided High Intensity Focused Ultrasound Tx of Soft Tissue Tumors
The goal of this project is to evaluate the safety and preliminary efficacy of ExAblate magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) surgery in the treatment of soft tissue tumors of the extremities.
- Trial name
- NCT01965002
- Testing
- MRgHIFU, Aspirin, Enoxaparin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Pejman Ghanouni
Breast Cancer
Partial Breast Irradiation in a Low-risk Population Screened With MRI
This is a pilot study to determine if partial breast irradiation (PBI) limited to the region of the tumor bed following lumpectomy in patients screened with MRI provides historically similar rates of local failure, limited acute…
- Trial name
- NCT01255553
- Testing
- Partial Breast Irradiation
- Where
- United States
- Sponsor
- University of Chicago
Heart Failure, Left Ventricular Dysfunction
Predicting Response to Cardiac Resynchronization Therapy in Heart Failure
This study will explore which characteristics of patients with heart failure will likely predict improvement after cardiac resynchronization (CRT), implantation of a pacemaker to improve heart function.
- Trial name
- NCT00359372
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Magnetic Resonance Imaging (MRI)
Post-marketing Safety Study in Participants of All Pathologies Who Receive Gadolinium-Based Contrast Agents (GBCAs) for Contrast-Enhanced Magnetic Resonance Imaging (MR) Examination
The purpose of this study is to prospectively collect data on the pattern of use for gadolinium-based contrast agents (GBCAs) in real-life setting with special reference to Clariscan after its commercial launch in Europe and in…
- Trial name
- NCT03455283
- Testing
- Clariscan, Gadolinium-Based Contrast Agents
- Where
- 2 sites in Germany, Norway
- Volunteers
- 2,118 people
- Sponsor
- GE Healthcare
Sleep Disturbances, Depression
Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Community Elders
The research team proposes a multi-year study with the first year focusing on the developmental phase. In this initial phase, we aim to recruit 40 participants (including healthcare staff and older adults) from Shuang-Ho Hospital…
- Trial name
- NIMDS (NCT07179172)
- Testing
- Mindfulness-Based Stress Reduction (MBSR) 8-Week Program
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Alzheimer's Disease, Healthy
The Effect of Acetylcholine on Memory and Attention
This study will examine whether enhancing the chemical acetylcholine in the brain can improve memory and attention. It will identify changes in brain function that occur during these cognitive tasks.
- Trial name
- NCT00001977
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Brain Tumor, Brain Necrosis
Development of MRF for Characterization of Brain Tumors After Radiotherapy
The purpose of this study is to discover the potential convenience and ease of using a Magnetic Resonance Imaging (MRI) technique, named Magnetic Resonance Fingerprinting (or MRF), to achieve high-quality images within a short…
- Conditions
- Brain Tumor, Brain Necrosis, Brain Metastases, Glioma
- Trial name
- NCT06101069
- Testing
- MRF in conjunction with IVIM MRI without contrast
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
MRI in Predicting Early Response to Chemotherapy in Patients With Locally Advanced Breast Cancer
RATIONALE: Diagnostic procedures such as MRI scans may help predict early response to treatment in patients with breast cancer undergoing chemotherapy.
- Trial name
- NCT00978770
- Testing
- systemic chemotherapy, diffusion-weighted magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cancer Clinical Trials Unit, Scotland
Atrial Fibrillation
Consistency of LGE-MRI Fibrosis and EAM Low-voltage Area
This study aims to: 1. Assess the consistency of LGE-MRI bi-atrial fibrosis and electroanatomical mapping of bi-atrial low voltage region 2.
- Trial name
- NCT06552845
- Testing
- LGE-MRI Scan
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China National Center for Cardiovascular Diseases
Arthritis, Rheumatoid, Synovitis
Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy
The safety profile and efficacy of combination therapy will be evaluated using methotrexate (MTX) and the nucleoside analog fludarabine in 40 patients with severe refractory rheumatoid arthritis.
- Trial name
- NCT00001677
- Testing
- Methotrexate, Fludarabine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
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