Clinical trials: Magnetic Resonance Imaging (MRI)
Chronic Stroke
Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients
In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.
- Trial name
- NCT03392519
- Testing
- Chronic stroke
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samsung Medical Center
Osteoid Osteoma
MR-HIFU Treatment of Painful Osteoid Osteoma
To determine treatment safety and efficacy of MR-HIFU ablation of painful Osteoid Osteoma (OO) in children and young adults.
- Trial name
- NCT04658771
- Testing
- MR-HIFU treatment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's National Research Institute
Rectal Cancer
Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial
To determine the maximum tolerated dose (MTD) of AZD6244 or AZD2171 when combined with pre-operative capecitabine and radiotherapy in patients with locally advanced rectal cancer.
- Trial name
- DREAMtherapy (NCT01160926)
- Testing
- AZD6244, Cediranib (AZD2171)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- The Christie NHS Foundation Trust
Lumbar Spinal Stenosis
Effectiveness and Safety of Korean Medicine for Lumbar Stenosis Patients With Sciatica
A prospective study investigating the effectiveness and safety in lumbar stenosis patients receiving integrative Korean medicine treatment at 3 locations of Jaseng Hospital of Korean Medicine through assessment of pain…
- Trial name
- NCT02975011
- Testing
- Herbal medicine, Chuna manipulation, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Jaseng Medical Foundation
Multiple Sclerosis
Artificial Intelligence-Assisted Magnetic Resonance Imaging for Quality, Efficiency and Equity in the National Health Service (NHS) Care of Multiple Sclerosis
Multiple Sclerosis (MS) is a long-term disease that affects over 150,000 people in the UK. Starting treatment early is important for managing Multiple Sclerosis (MS).
- Trial name
- AssistMS (NCT07111637)
- Testing
- AI software
- Where
- United Kingdom
- Volunteers
- 1,336 people
- Sponsor
- Queen Mary University of London
Pancreatic Cancer
Prediction of Surgical Resectability After FOLFIRINOX Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Cancer: the Role of Diffusion Weighted Magnetic Resonance Imaging, Radiomics and Liquid Biopsy (PeRFormanCe Trial)
In this prospective study, new diagnostic tools will be explored for patients with borderline resectable and locally advanced pancreatic ductal adenocarcinoma (BR or LAPDA) who undergo neoadjuvant chemotherapy with FOLFIRINOX.
- Trial name
- PeRFormanCe (NCT05298722)
- Testing
- Imaging analysis of CT-scan and MRI with radiomics and genetic analysis of peripheral blood samples and questionnaires.
- Where
- 8 sites in Belgium, Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Magnetic Resonance Spectroscopy
Non-Invasive Monitoring Of Metabolite Levels Using Novel And Adapted MR Spectroscopy Techniques
This Swiss National Science Foundation (SNF) funded project and the linked European project aim to improve magnetic resonance (MR) methods, specifically MR spectroscopy and metabolic imaging (making them more sensitive and…
- Trial name
- NIMM_MRS (NCT05165537)
- Testing
- NIMM_MRS
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Treatment Resistant Depression, Transcranial Magnetic Stimulation
rTMS Intervention on Motivational Anhedonia of Treatment Resistant Depression and Brian Network Mechanism
Study of individualized accurate targeting rTMS intervention on motivational anhedonia of treatment resistant depression and brain network mechanism
- Conditions
- Treatment Resistant Depression, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging, Event-Related Potentials
- Trial name
- rTMS (NCT03991572)
- Testing
- repeated transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Myocardial Perfusion Imaging, Magnetic Resonance Imaging
Myocardial Perfusion MRI
The object of this study is to compare four different dosages of Gadavist 1.0 in cardiac Magnetic Resonance Tomography (MRT) imaging with the imaging results of a cardiac SPECT examination in terms of diagnostic quality.
- Trial name
- NCT01490294
- Testing
- Gadobutrol (Gadavist,Gadovist, BAY86-4875)
- Where
- 14 sites in Austria, Germany and 2 more
- Volunteers
- 232 people
- Sponsor
- Bayer
Vestibular Schwannoma, Unilateral Vestibular Deficit
Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma
The goal of this clinical trial is to visualize the possible activation of vestibular centers in the brain using in patiens with unilateral vestibular damage, specifically in patients after vestibular schwannoma surgery.
- Conditions
- Vestibular Schwannoma, Unilateral Vestibular Deficit, Healthy
- Trial name
- NCT07130851
- Testing
- vestibular schwannoma resection
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marketa Bonaventurova
Vestibular Schwannoma
Response Prediction After GKS in Patients With Vestibular Schwannoma Using DCE MR Imaging
Response Prediction after Gamma Knife Surgery (GKS) in Patients with Vestibular Schwannoma using Dynamic Contrast-Enhanced (DCE) MR Imaging
- Trial name
- NCT03097822
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease, Coronary Microvascular Disease
Whole-Heart Myocardial Blood Flow Quantification Using MRI
This study hopes to provide significant technical improvement in a Myocardial Blood Flow (MBF) cardiac magnetic resonance (CMR) quantification technique to address challenges and technical limitations for MBF CMR.
- Trial name
- NCT03064295
- Testing
- Myocardial Perfusion Cardiac MRI., Contrast, Pharmacologic Stress Agent
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Coronary Artery Disease
Accelerated Stress CMR in Coronary Artery Disease
This study will evaluate the diagnostic performance of an accelerated stress CMR protocol, comparing it with that of standard CMR assessment.
- Trial name
- NCT05221762
- Testing
- Cardiovascular magnetic resonance (CMR)
- Where
- United Kingdom
- Volunteers
- 167 people
- Sponsor
- University of Leicester
Ankylosing Spondylitis
Open Label Clinical Trial With Rituximab (MabThera ®) in Ankylosing Spondylitis
To evaluate the efficacy and safety of rituximab when added to NSAIDs and/ or methotrexate both for TNFalpha inhibitor naïve or TNFalpha inhibitor failure patients with moderate to severe ankylosing spondylitis
- Trial name
- NCT00432653
- Testing
- rituximab
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
Recurrent Malignant Glioma
Avastin / Irinotecan in Patients With Recurrent or Progressive Malignant Glioma
Malignant glioma are the most common and aggressive primary brain tumors in adults. Despite advances in multimodal treatment including surgery, radiation and chemotherapy, most patients have a dismal prognosis of 9-15 months…
- Trial name
- AVIRMA01-09 (NCT01144988)
- Testing
- Bevacizumab / Irinotecan
- Where
- 2 sites in Austria
- Volunteers
- 35 people
- Sponsor
- Medical University Innsbruck
Obstructive Sleep Apnea
Magnetic Resonance Imaging in Obstructive Sleep Apnea
There is a fundamental gap in the investigators ability to design effective surgical treatment of obstructive sleep apnea (OSA) for the 30-40% of patients who cannot tolerate non-surgical treatment.
- Trial name
- MRI in OSA (NCT02207127)
- Testing
- MRI, DISE, and Surgery
- Where
- United States
- Sponsor
- University of Southern California
Healthy Volunteers
Normative Cardiovascular Magnetic Resonance Values for Measurement of Cardiovascular Structure and Function at MCMR
Cardiovascular magnetic resonance (CMR) imaging is an important clinical and research tool. Measurements of cardiovascular structure and function can vary according to scanner vendor, scanner field strength, imaging sequence and…
- Trial name
- NORMAL MCMR (NCT05066269)
- Where
- United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Prostate Cancer
Prostate Cancer Localization With a Multiparametric Magnetic Resonance (MR) Approach
The primary objective of this prospective multi-centre study is to prove the diagnostic accuracy of in vivo 3T multi-modality Magnetic Resonance Imaging (high resolution T2-weighted MRI, DCE-MRI, MRSI and DWI techniques) in…
- Trial name
- PCa-MAP (NCT01138527)
- Testing
- MRI examination
- Where
- 9 sites in United States, Austria and 6 more
- Volunteers
- 148 people
- Sponsor
- Radboud University Medical Center
Healthy Volunteers
Assessment of Magnetic Resonance Imaging Neurography and Tractography for Preoperative Mapping of Pelvic Nerves
This project aims at assessing two MRI acquisition methods, neurography and tractography, for the visualization of pelvic nerves.
- Trial name
- Neuro-Tracto (NCT02582346)
- Testing
- MRI acquisition - no contrast agent
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IHU Strasbourg
Prostate Cancer (Diagnosis)
Evolution of Lesions in Repeated Biparametric Prostate Magnetic Resonance Imaging
The goal of this clinical trial is to prospectively investigate the evolution of lesions in biparametric magnetic resonance imaging (bpMRI) of the prostate in men with no clinically significant prostate cancer (csPCa) in their…
- Trial name
- REMRI (NCT07369570)
- Testing
- MRI
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Eastern Finland
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