Clinical trials: Magnetic Resonance Imaging (MRI)
Parkinson Disease, Physical Activity
Neuroplasticity in Parkinson´s Disease After Training
This project aims to determine the effects of the HiBalance program on neuroplastic changes in people with mild to moderate Parkinson´s disease.
- Conditions
- Parkinson Disease, Physical Activity, Gait Disorders, Neurologic, Neural Degeneration
- Trial name
- BETA-PD (NCT03213873)
- Testing
- HiBalance, Speech and communication therapy
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Karolinska Institutet
Psychotic Disorders, Bipolar Disorder
Comparison of Aripiprazole Versus Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI
The purpose of this study is to compare abdominal weight gain and fat distribution in people taking aripiprazole versus risperidone or quetiapine, to people not taking any of these antipsychotic medications.
- Conditions
- Psychotic Disorders, Bipolar Disorder, Metabolic Syndrome X
- Trial name
- CALM (NCT01739127)
- Testing
- Aripiprazole, Risperidone/Quetiapine
- Where
- Canada
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Endometriosis, Mobility Limitation
ENDOMETRIOSIS - MRI
Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes…
- Conditions
- Endometriosis, Mobility Limitation, Magnetic Resonance Imaging, Diagnosis
- Trial name
- ENDO-MRI (NCT05779462)
- Testing
- Dynamic MRI Sequence
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Multiple Sclerosis
Study of myMS in Participants With a Diagnosis of Multiple Sclerosis
This is a pilot study looking at the feasibility of a mobile application (app) to collect data from active tasks (questionnaires, 6Mapp™, COGapp™, VISapp™), clinical magnetic resonance imaging information and conduct genome-wide…
- Trial name
- NCT03111394
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Southern California
Breast Neoplasms
Using Hyperpolarized [1-13C]Pyruvate to Detect Cardiotoxicity
The anthracycline doxorubicin, first introduced in the 1960's, continues to be an effectively utilized antineoplastic drug. Even at relatively low cumulative doses there is risk of cardiotoxicity.
- Trial name
- HPCardiotox (NCT03685175)
- Testing
- Formal study using hyperpolarized 13C-pyruvate injection, Feasible study using hyperpolarized 13C-pyruvate injection
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Bipolar
Combined Cytidine and Creatine-containing Drug in the Treatment of the Bipolar Depression
This research is aimed to investigate the efficacy and safety of the creatine and cytidine augmentation in treating bipolar depression and to evaluate changes in relevant brain biochemical metabolism using proton and phosphorous…
- Trial name
- NCT02625779
- Testing
- Valproate and Cytidine-containing Drug, Valproate and Creatine-containing Drug
- Where
- South Korea
- Sponsor
- Ewha Womans University Mokdong Hospital
Hydrocephalus
Magnetic Resonance Elastography in Hydrocephalus
The purpose of this project is to assess the utility of a new magnetic resonance technique called magnetic resonance elastography (MRE) in the non-invasive diagnosis of normal pressure hydrocephalus.
- Trial name
- NCT02230124
- Testing
- MRE
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Myocardial Infarction
Myocardial Oedema in Acute Myocardial Infarction (AMI)
Despite recent improvements in treatment, myocardial infarction (heart attack) is still a leading cause of illness and death in the UK.
- Trial name
- NCT00987259
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
Depressive Disorder, Depressive Disorder, Major
Brain Imaging, Genetics and Treatment for Major Depression
Background: Antidepressants help many people with depression, however, some do not seem to benefit as much. Currently, it is not possible to determine who will improve with certain antidepressants.
- Conditions
- Depressive Disorder, Depressive Disorder, Major, Depression
- Trial name
- NCT01568684
- Testing
- Citalopram
- Sponsor
- National Institute of Mental Health (NIMH)
Myocardial Diseases, Perfusion Imaging
Validation of Myocardial Perfusion and Extracellular Volume Assessment Using Photon-Counting Computed Tomography (PCCT) Compared With Cardiac Magnetic Resonance (CMR) in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI)
Cardiovascular diseases are the leading cause of death worldwide, responsible for about 30% of all deaths. This substantial burden highlights the need for accurate diagnostic tools that help doctors detect heart disease early and…
- Conditions
- Myocardial Diseases, Perfusion Imaging, Stress Perfusion, Myocardial Fibrosis
- Trial name
- NCT07799363
- Testing
- Stress myocardial perfusion imaging with PCCT. Extracellular volume quantification with PCCT.
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska University Hospital
Crohn's Disease, CAM
Efficacy of Acupuncture and Moxibustion Treatment in Patients With Quiescent Crohn's Disease:Evaluation With fMRI
The purpose of this study is to determine whether acupuncture or moxibustion therapies are effective in the treatment of Crohn's disease.
- Trial name
- NCT01696838
- Testing
- electroacupuncture, moxibustion
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Vertigo
Diagnosis Of Vertigo With New Imaging
The purpose of this study is to determine the potential usefulness of new functional MRI in diagnostic assessment of patients presenting with vertigo.
- Trial name
- NCT00593216
- Testing
- Functional MRI imaging
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Boston University
Irritable Bowel Syndrome
Pilot Study of the Physiological Effects of an Integrative Medicine Approach in Irritable Bowel Syndrome
Although underutilized, what is emerging as one of the best ways of evaluating inflammation in the body, particularly in difficult to observe regions, is through the use of Fluorodeoxyglucose (FDG) positron emission tomography…
- Trial name
- IBS (NCT03370614)
- Testing
- IBS Group, Healthy Control Group
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Very Preterm Maturity of Infant, Very Low Birth Weight Infant
Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment
Human milk has several well-established benefits but does not adequately meet the increased nutritional demands of the growing preterm infant, necessitating additional nutrient supplementation in a process known as fortification.
- Trial name
- THRIVE (NCT06266455)
- Testing
- Standardized Fortification, Adjustable Fortification
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's National Research Institute
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from…
- Conditions
- Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder
- Trial name
- BBPP (NCT01570426)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Prolapse Genital, Anatomical Pathological Condition
The Change in Vaginal Axis on MRI After Uterus Preserving Laparoscopic Lateral Mesh Suspension
Laparoscopic lateral mesh suspension is emerged as a practical, safe and feasible alternative to sacropexy to treat female genital apical prolapse.
- Trial name
- NCT03772015
- Testing
- Magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Gliosarcoma, Glioma
Pilot Study Using Amide Proton Transfer Magnetic Resonance Imaging Distinguishing Glioma
This research is being done to study the pattern of changes in various parts of the magnetic resonance imaging (MRI) studies that patients have done to help plan their radiation therapy and to evaluate the effects of therapy.
- Trial name
- NCT03843814
- Testing
- APT MRI
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Localization-related Epilepsy, Partial Epilepsy
Improving Lesion Detection in Children With Magnetic Resonance Imaging (MRI)-Negative Partial Epilepsy Using Diffusion Tensor Imaging
Focal cortical dysplasia is one of the most common lesions responsible for medically refractory epilepsy in the pediatric population.
- Trial name
- NCT00894478
- Testing
- Diffusion Tensor Imaging (DTI), Magnetoencephalography
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy
Technical Development of up to 7T Magnetic Field Strength
The objective of this study is to determine whether these new image acquisition strategies and techniques using of up to 7T can produce meaningful structural and physiological information that can serve to improve our…
- Trial name
- NCT02666638
- Testing
- Control Volunteers, Clinical Volunteers
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Low Grade Prostate Cancer
Laser Based Focal Ablation of Low Grade Prostate Cancer
The purpose of this study is to evaluate the safety of MRI-guided laser-induced thermal therapy of biopsy confirmed low-risk prostate cancer.
- Trial name
- NCT01192438
- Testing
- Laser-based thermotherapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Chicago
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