Clinical trials: Magnetic Resonance Imaging (MRI)
Prostate Cancer
Improved Prostate Cancer Diagnosis - Combination of Magnetic Resonance Imaging and Biomarkers
Prostate cancer has been the most common cancer in men in Finland over the last ten years. Prostate-specific antigen (PSA) plays an important role in screening of prostate cancer.
- Trial name
- IMPROD (NCT01864135)
- Testing
- 3T MRI (Magnetom Verio 3T, Erlangen, Germany), Transrectal ultrasound (Bk Medical Pro Focus Ultraview 2202 system)
- Where
- Finland
- Volunteers
- 175 people
- Sponsor
- Turku University Hospital
Breast Cancer
Breast Cancer Screening With MRI in Women Aged 50-75 Years With Extremely Dense Breast Tissue: the DENSE Trial
The purpose of this study is to determine the cost-effectiveness of biennial screening with mammography and MRI compared to mammography alone in women aged 50-75 years and who show > 75% mammographic density.
- Trial name
- NCT01315015
- Testing
- Contrast enhanced breast MRI
- Where
- 9 sites in Netherlands
- Volunteers
- 40,373 people
- Sponsor
- UMC Utrecht
Spinal Cord Injuries, Bladder, Neurogenic
Functional Changes in the Brain After Tibial Nerve Stimulation: a Pilot Study
The lower urinary tract is innervated by the autonomous (sympathetic, parasympathetic) and the somatic nervous system. Afferent information from the lower urinary tract (LUT) (e.g.
- Trial name
- NCT03908047
- Testing
- magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Childhood Brain Neoplasm
In Vivo Characterization of Macrophages in Pediatric Patients With Malignant Brain Tumors Using Ferumoxytol-enhanced MRI
This pilot early phase I trial studies how well ferumoxytol-enhanced magnetic resonance imaging (MRI) correlates with inflammatory (macrophage) responses in pediatric patients with malignant brain tumors.
- Trial name
- NCT03179449
- Testing
- Diagnostic (ferumoxytol-enhanced MRI), Surgery, Ferumoxytol
- Sponsor
- Michael Iv
Alcoholism, Cocaine Addiction
The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues
High relapse rates among substance dependent individuals are likely due to a combination of factors that involve limbic circuits in the brain involved in craving, including vulnerability to salient cues.
- Conditions
- Alcoholism, Cocaine Addiction, Drug Addiction
- Trial name
- addictionTBS (NCT02939352)
- Testing
- Real continuous Theta Burst Stimulation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Medical University of South Carolina
Traumatic Brain Injury
Neurorehabilitation After Traumatic Brain Injury: Functional Magnetic Resonance Imaging Study
The current study aims to better understand cerebral plasticity mechanisms to optimize non-pharmacological rehabilitation approaches for patients with traumatic brain injury.
- Trial name
- RemCog-TC (NCT02698449)
- Testing
- transcranial direct current stimulation, Specific cognitive rehabilitation, Nonspecific cognitive rehabilitation
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Toulouse
Breast Cancer
Diffusion Weighted Magnetic Resonance Imaging of the Breast During Chemotherapy: Response Evaluation
Evaluation of the response to chemotherapy in breast cancer patients by the use of Diffusion-weighted magnetic resonance imaging of the breast before the start of chemotherapy, after one and 3 cycles of therapy and at the end of…
- Trial name
- NCT01684735
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity, Visceral, Obesity; Endocrine
Study of Lipolysis of Visceral Reserve Fat Using Tecar Therapy.
The Scope of this study is to assess the visceral and subcutaneous fat loss in patients having Tecar (Radiofrequency) Therapy and its effects on other anthropometric variables, adipokines and inflammation.
- Trial name
- NCT06377358
- Testing
- Tecar Therapy
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- CAPENERGY MEDICAL, SL
Cervical Cancer
A Pilot Study Using Magnetic Resonance (MR) to Assess Cervix Motion During Radiotherapy Treatment.
The standard treatment for locally advanced cervical cancer is concurrent chemo-radiotherapy. This treatment is associated with long term side effects in around half of patients with up to 10% suffering from grade 3-4 toxicity.
- Trial name
- MR Cervix (NCT03101306)
- Testing
- MR scans
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- The Christie NHS Foundation Trust
MRI, Osteoarthrosis
Osteoarthrosis on 7.0T Magnetic Resonance Imaging
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting osteoarthrosis. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater…
- Trial name
- NCT05343104
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Prostate Cancer
MR-guided Focused Ultrasound Treatment of Prostate Cancer: Focal Therapy for Locally Non-Advanced Disease
Since prostate specific antigen (PSA) was introduced as a clinical screening tool for prostate cancer, more men are diagnosed with small foci of cancers instead of the advanced disease.
- Trial name
- NCT01522118
- Testing
- ExAblate 2100; InSightec
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- University of Roma La Sapienza
Delirium, Sedation Complication
The Relationship Between Fasting Time and Delirium
We investigated the relationship between fasting times and delirium in children undergoing MRI under anesthesia. Paediatric Anaesthesia Emergence Delirium (PAED) scale, last oral intake time and type of food (solid-liquid) and…
- Conditions
- Delirium, Sedation Complication, Magnetic Resonance Imaging, Fasting
- Trial name
- NCT05567718
- Testing
- Paediatric Anaesthesia Emergence Delirium scale
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Myocardial Infarction, Myocardial Ischemia
18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability
This study is designed as a prospective observational feasibility study. The investigators will study whether vulnerable plaques on OCT (fibrous cap ≤ 70 μm) show a locally increased uptake of 18F-choline on PET-MRI compared to…
- Conditions
- Myocardial Infarction, Myocardial Ischemia, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT03252990
- Testing
- PET-MRI, Optical Coherence Tomography
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pulmonary Arterial Hypertension
Spironolactone for Pulmonary Arterial Hypertension
Background: High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. In spite of recent advances in treatment, the death rate remains unacceptably high.
- Trial name
- NCT01712620
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Aging
Magnetic Resonance Imaging (MRI) and Eye-tracking Predictive Markers of Cognitive Ageing.
This research proposes to investigate physiological and cognitive markers of locus coeruleus (LC) neuronal integrity and function in cognitively-healthy participants over 60 years old.
- Trial name
- PrediCog (NCT06058897)
- Testing
- MRI, eye-tracking, cognitive exams
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Rheumatoid Arthritis
The Effect of Certolizumab Pegol on MRI Synovitis and Bone Edema in Rheumatoid Arthritis Patients
The purpose of this study is to determine whether Certolizumab pegol can rapidly reduce the inflammatory changes and inhibit erosions on hand and wrist MRI in patients with active moderate to severe rheumatoid arthritis.
- Trial name
- PICS (NCT01213017)
- Testing
- certolizumab pegol
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Oklahoma Medical Research Foundation
Anterior Cruciate Ligament Tear
Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique
The purpose of the study is a clinical evaluation with special regard to magnetic resonance imaging and functional performance at least one year after injury / surgery in all three groups (subjects who underwent InternalBrace…
- Trial name
- NCT02760589
- Where
- Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- AUVA
Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC))
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease associated with fibrofatty myocardial replacement, ventricular arrhythmias, and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET, Cardiac Magnetic Resonance Imaging
- Trial name
- FAPI-ARVC (NCT07563660)
- Testing
- 68Ga-DOTA-SA-FAPI PET/CT
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul University - Cerrahpasa
Congenital Heart Disease
Improved Diagnosis of Congenital Heart Disease by Magnetic Resonance Imaging Using Vasovist
Magnetic Resonance Imaging (MRI) is an effective and radiation free method of diagnosing Congenital Heart Disease (CHD). MRI works by taking images of the anatomy and physiology.
- Trial name
- CHD Vasovist (NCT00668824)
- Testing
- Vasovist
- Where
- United Kingdom
- Sponsor
- Guy's Hospital
Breast Cancer
Presurgical Therapy With Lapatinib to Explore Molecular Determinants of Response to EGFR/erbB2 Targeted Therapy
The purpose of this study is to see what kinds of breast tumors will respond to lapatinib. Lapatinib is an experimental medicine which may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT00343759
- Testing
- Lapatinib
- Where
- United States
- Sponsor
- University of Pennsylvania
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