Clinical trials: Magnetic Resonance Imaging (MRI)
Epilepsies, Partial
High-resolution Multi-parametric Magnetic Resonance Imaging for Focal Epilepsy
Patients with focal epilepsy often have diagnostic difficulties as their culprit for seizures are difficult to be picked up using conventional imaging.
- Trial name
- NCT06550726
- Testing
- Magnetic Resonance Imaging
- Where
- Hong Kong
- Volunteers
- 66 people
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer, Magnetic Resonance Imaging
Detection of Clinically Significant Prostate Cancer Using Transperineal Targeted Biopsy Compared to Standard Transrectal Biopsy
Prostate biopsies are currently the gold standard for the diagnosis of prostate cancer. Many biopsies, however, are unnecessary or cannot detect significant prostate cancer (PCa).
- Conditions
- Prostate Cancer, Magnetic Resonance Imaging, Target Lesion, Fusion Biopsy
- Trial name
- NCT03044197
- Testing
- MRI/ultrasound transperineal prostate biopsy, transrectal ultrasound-guided prostate biopsy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Fibromyalgia
Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia
The purpose of this study is to determine the effects of mild cranial electrical stimulation on pain, fatigue, sleep disturbances, perceived stress, blood pressure, and functional status in persons with fibromyalgia.
- Trial name
- NCT00928720
- Testing
- CES device
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Virginia
Epilepsy
Brain Infusion of Muscimol to Treat Epilepsy
This study will examine the safety and effectiveness of infusing a chemical called muscimol into the brain to control seizures in patients with intractable epilepsy (frequent seizures that persist despite therapy).
- Trial name
- NCT00005925
- Testing
- Muscimol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy
Functional Magnetic Resonance Imaging of Human Hypothalamic Responses to Oral Temperature and Glucose Sensing
The study will consist of four occasions with one week between the occasions. fMRI will be performed to monitor hypothalamic activity before and after an ingestion of 1 of the following 4 stimuli (300 ml of each): water at room…
- Trial name
- COLD (NCT03181217)
- Testing
- water 0, water 22, Glucose 0
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Atherosclerotic Carotid Disease, Atheroma
Effects Of Atorvastatin On Macrophage Activity And Plaque Inflammation Using Magnetic Resonance Imaging
A new way of scanning narrowing in the arteries (main blood vessels) caused by fatty deposits known as plaques has been developed. Heart attacks and strokes occur when plaques become inflamed, depending on the artery affected.
- Conditions
- Atherosclerotic Carotid Disease, Atheroma, Atherosclerosis
- Trial name
- NCT00368589
- Testing
- atorvastatin
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- GlaxoSmithKline
Headache, Migraine
The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA) on Healthy Volunteers
Studying Pituitary adenylate cyclase-activating peptide 27 (PACAP27) effects on extra- and intracerebral arteries assessed by MRA on healthy volunteers.
- Trial name
- NCT03560024
- Testing
- PACAP27
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Thalassemia, Non-transfusional-dependent Thalassemia (NTDT), Myeloplastic Dysplasia (MDS), Other Anemia
An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)
Iron, one of the most common elements in nature and the most abundant transition metal in the body, is readily capable of accepting and donating electrons.
- Trial name
- NCT01736540
- Testing
- MRI scan
- Where
- 13 sites in Australia
- Volunteers
- 243 people
- Sponsor
- Novartis Pharmaceuticals
Magnetic Resonance Imaging, Cerebral Venous Sinus Thrombosis
Application CT and MRI in Cerebral Venous Sinus Thrombosis
Cerebral venous thrombosis (CVT) is a rare disease, and with poor prognosis. Computed tomography (CT) andmagnetic resonance imaging (MRI) are the most commonly used image modalities for patients with non-specific neurologic…
- Conditions
- Magnetic Resonance Imaging, Cerebral Venous Sinus Thrombosis, Computer Tomographgy
- Trial name
- NCT04966182
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atherosclerosis, Carotid Artery Disease
Magnetic Resonance Imaging (MRI) Characterization of Carotid Plaque and Prediction of End-organ and Clinical Outcomes
The Canadian Atherosclerosis Imaging Network (CAIN) is a pan-canadian imaging network funded through grants from the Canadian Foundation for Innovation (CFI) and the Canadian Institutes of Health Research (CIHR).
- Trial name
- NCT01440296
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Torn Meniscus
Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy
The aim of this study is to describe changes at the site of the study patient's articular cartilage lesion on the femoral condyle with multiple magnetic resonance imaging (MRI) outcomes 6 months after treatment using one of three…
- Trial name
- MILE (NCT00613535)
- Testing
- Mechanical debridement, Paragon T2, Lavage debridement
- Where
- 10 sites in United States
- Volunteers
- 165 people
- Sponsor
- Smith & Nephew, Inc.
Endometriosis, Reproductive System Disorder
Developing an US-MRI Biomarker Fusion Model for Endometriosis
Single centre, prospective, observational, cohort study looking to develop a database representing the variability of disease and imaging seen in women with clinically diagnosed endometriosis, awaiting laparoscopic surgery.
- Trial name
- DEFEND (NCT04974710)
- Testing
- Outpatient MRI
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Perspectum
Brain Injury, Fetus and Neonate
Diffusion-Tensor Magnetic Resonance Imaging (MRI) and the Evaluation of Perinatal Brain Injury
The researchers' objective is to use diffusion-tensor imaging (DTI) to evaluate infants diagnosed with cerebral white matter injury during the neonatal period and identify antenatal risk factors, electronic fetal heart rate…
- Trial name
- NCT00131859
- Testing
- Diffusion-tensor imaging
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Radiculopathy Lumbar
Clinical and MRI Factors Associated With Procedural Difficulty in Lumbar TFESI
The technical difficulty of transforaminal epidural steroid injection (TFESI) may be influenced by patient-related characteristics, the target spinal level, a history of lumbar surgery, the presence of spinal instrumentation, and…
- Trial name
- NCT07870720
- Volunteers
- 190 people
- Sponsor
- Selcuk University
Myocardial Infarction
Ferumoxytol for Magnetic Resonance Imaging of Myocardial Infarction
The investigators wish to examine whether a novel 'nanoparticle' of iron oxide, administered intravenously allows an area of heart muscle damage after heart attack to be visualised using a magnetic resonance scanner.
- Trial name
- NCT01323296
- Testing
- Ferumoxytol
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Edinburgh
Chronic Coronary Syndrome
CMR-derived Quantitative Perfusion for Prediction of FFR
Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR)…
- Trial name
- NCT07018778
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Kerckhoff Klinik
Colorectal Liver Metastases, Colorectal Neoplasms
Multimodal Survival Prediction Model for Colorectal Liver Metastases Post-Operation
The purpose of this study is to construct and validate a multimodal survival prediction model by integrating 3D radiomics features derived from preoperative magnetic resonance imaging (MRI) with systemic clinical baseline…
- Conditions
- Colorectal Liver Metastases, Colorectal Neoplasms, Liver Neoplasms
- Trial name
- NCT07830576
- Testing
- Multimodal Predictive Evaluation
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Anhui Provincial Hospital
Metabolic Dysfunction-associated Steatotic Liver Disease
Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease
Muscle changes including myosteatosis are reported as highly prevalent in metabolic dysfunction-associated steatotic liver disease (MASLD). Recent studies highlighted a link between muscle fat content and liver disease severity.
- Trial name
- MYO-MASLD (NCT06506513)
- Testing
- High-intensity interval training, Moderate intensity exercise training, Low intensity exercise training
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Breast Cancer
Evaluation of Magnetic Resonance Imaging (MRI) vs Molecular Breast Imaging (Tc-MBI) in Breast Cancer Patients
The objective of this study is to evaluate the usefulness of Tc-99m Sestamibi Molecular Breast Imaging as an imaging modality for breast cancer screening.
- Trial name
- NCT02024074
- Testing
- Sestamibi (Tc-MBI) scan of the breast
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Emory University
Emotional Stress
The Flourishing Project: Evaluation of the Effectiveness of a Well-being Program
This protocol proposes a well-being program based on meditation and Positive Psychology principles such as human development, the improvement of virtues, quality of life and well-being.
- Trial name
- Flourishing (NCT02164188)
- Testing
- Flourishing protocol
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
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