Clinical trials: Magnetic Resonance Imaging (MRI)
Congenital Heart Disease
Imaging by 4 DFlow in Patients With Tetralogy of Fallot
Conventionnal cadiac magnetic resonance (CMR) is the reference to assess changes in right heart flow and pulmonary artery hemodynamics in patients with repaired Tetralogy of Fallot.
- Trial name
- 4DFlowFallot (NCT03542968)
- Testing
- magnetic resonance imaging
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Prostate Cancer
Using Magnetic Resonance Imaging (MRI) to Guide Differential-Dose Prostate Brachytherapy
In standard prostate brachytherapy treatment, the seeds are placed throughout the prostate to treat the entire gland. This is done because, in the past, it was impossible to know where the cancer was located within the prostate.
- Trial name
- NCT01913197
- Testing
- An MRI-based technique to identify prostate cancer
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Pulmonary Arterial Hypertension
Spironolactone for Pulmonary Arterial Hypertension
Background: High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. In spite of recent advances in treatment, the death rate remains unacceptably high.
- Trial name
- NCT01712620
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cervical Cancer
Image Based Brachytherapy in Locally Advanced Cervical Cancers - a Randomized Controlled Trial
Purpose of the study is to determine whether Image based brachytherapy is superior in terms of local control to Conventional radiograph based brachytherapy in locally advanced cervical cancers in a Phase III randomized setting.
- Trial name
- COMBAT-Cx (NCT03005743)
- Testing
- Magnetic Resonance Image based Brachytherapy, Conventional Radiograph based Brachytherapy
- Where
- India
- Volunteers
- 1,050 people
- Sponsor
- Tata Memorial Hospital
Cerebrovascular Circulation
Blood Flow Measurement Using Quantitative Magnetic Resonance Angiography and Duplex Sonography
The aim of the study is to assess the correlation of blood flow measurement in cervical and intracranial arteries between quantitative magnetic resonance angiography (qMRA) and duplex sonography (DS) and…
- Trial name
- NCT03591523
- Testing
- Quantitative MR angiography, Duplex sonography
- Where
- Czechia
- Volunteers
- 21 people
- Sponsor
- Palacky University
Magnetic Resonance Imaging, Ovarian Function
Fertility After Transvaginal Surgery or Uterine Artery Embolization Combined With Uterine Curettage in Patients With Cesarean Scar Pregnancy
To investigate the fertility in patients after treatment by transvaginal surgery or uterine artery embolization combined with uterine curettage
- Conditions
- Magnetic Resonance Imaging, Ovarian Function, Menstruation
- Trial name
- NCT02933190
- Testing
- transvaginal surgery；UAE and D&C
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
PTSD
Precise Transcranial Magnetic Stimulation for Post-traumatic Stress Disorder
The purpose of this study is to investigate the efficacy and safety of repetitive transcranial magnetic stimulation under precise localization for post-traumatic stress disorder
- Trial name
- NCT05544110
- Testing
- Active transcranial magnetic stimulation
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Xijing Hospital
Dissecting Aneurysm of Cerebral Artery
Dynamic Contrast-Enhanced Magnetic Resonance Imaging Analysis for Prognosis of Intracranial Dissecting Aneurysm With Intramural Hematoma After Endovascular Treatment
This study will evaluate the feasibility to predict the prognosis of IDA with IMH by DCE-MRI and provide theoretical basis for the prognosis and intervention of the disease.
- Trial name
- DEMAT (NCT03940859)
- Testing
- intracranial stent, flow diverter and coils
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Neurosurgical Institute
Colorectal Cancer, Liver Metastases
A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer
The researchers are doing this study to see if one session of high-dose contrast-enhanced MRI-guided SBRT (stereotactic body radiation therapy) is effective for colorectal cancer that has spread to the liver.
- Trial name
- NCT06130280
- Testing
- MR Guided Single Fraction Stereotactic Body Radiation Therapy (SBRT)
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Non-invasive Diffusion-weighted Imaging, Magnetic Resonance Cholangiopancreatography
Non-invasive Diffusion-weighted Imaging With MRCP in the Diagnosis of Neoplastic Biliary Obstruction
This study aims to evaluate the diagnostic value of non-invasive diffusion-weighted magnetic resonance imaging (DW-MRI) in detecting neoplastic biliary obstruction.
- Conditions
- Non-invasive Diffusion-weighted Imaging, Magnetic Resonance Cholangiopancreatography, Diagnosis, Neoplastic Biliary Obstruction
- Trial name
- NCT07108725
- Testing
- Magnetic Resonance Cholangiopancreatography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- The General Authority for Teaching Hospitals and Institutes
Portal Hypertension
Non-Invasive Portal and Hepatic Vein Pressure Estimation
Background Portal hypertension (PH) is a spectrum of complications of end-stage liver disease (ESLD) and cirrhosis, with severe manifestations including ascites and gastroesophageal varices.
- Trial name
- NONEEDLES (NCT06210178)
- Testing
- Magnetic Resonance Imaging
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Stroke
Stroke Motor Recovery for the Hand and Fingers
The goal of this clinical trial is to compare two rehabilitation methods to improve finger movements in people who have had a stroke.
- Trial name
- NCT06604143
- Testing
- Quality Training, Goal Training
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Toronto
Breast Cancer
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Breast Cancer
The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC…
- Trial name
- USmBRT-B (NCT04431674)
- Testing
- Definity Suspension for Injection
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sunnybrook Health Sciences Centre
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study
The main purpose of this study is to measure the amyloid burden, defined as extracellular volume (ECV) assessed by Magnetic Resonance Imaging (MRI) over time in a subset of up to 150 participants enrolled in ION-682884-CS2…
- Trial name
- NCT06073574
- Testing
- Cardiac MRI
- Where
- 11 sites in United States, Italy and 2 more
- Volunteers
- 160 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Magnetic Resonance Imaging, Vascular Complications
Qualitative and Quantitative Evaluation of Vascular Flows of Radial, Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI
Allotransplants of vascularized composite tissues are subject to chronic vascular rejection, which can lead to graft loss. Currently, no imaging technique allows a reproducible quantitative exploration of the arterial trees of…
- Conditions
- Magnetic Resonance Imaging, Vascular Complications, Transplantation, Radial Artery
- Trial name
- FLOWHAND (NCT04257747)
- Testing
- MRI acquisitions, Doppler ultrasound procedure
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Epilepsy, HHV6B Infection
Relationship of HHV-6B Virus to Seizures and Brain Injury
This study will look for evidence that a virus called HHV-6B may be related to seizures and to a form of brain injury called mesial temporal sclerosis that is associated with seizures.
- Trial name
- NCT00597285
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
ST Segment Elevation Myocardial Infarction
Early Prediction of QFR in STEMI-I
The study intends to provide important data on whether the noval method using quantitative flow ratio could predict microvascular dysfunction.
- Trial name
- EARLYmyo-QFR-I (NCT03780335)
- Testing
- Computation of quantitative flow ratio
- Volunteers
- 162 people
- Sponsor
- RenJi Hospital
Meniscus Tears
Magnetic Resonance Imaging to Assess Changes in Meniscus Vascularity
The menisci in the knee joint are important for normal functioning of the knee. Meniscus tears are amongst the commonest of injuries to the knee.
- Trial name
- MOVE (NCT02363140)
- Testing
- Will undergo a single MRI assessment with intravenous dye, pre and post surgery MRI scan
- Volunteers
- 48 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Intracerebral Haemorrhage
Ischaemic Lesions in Acute Intracerebral Haemorrhage
The aim of this observational study is to determine how and why inadequate brain blood flow occurs after bleeding in patients with intracerebral haemorrhage (ICH).
- Trial name
- CHALLENGE-ICH (NCT06410274)
- Testing
- Transcranial Doppler ultrasonography (TCD)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Leicester
Breast Cancer
Biomarkers and Cardiac MRI as Early Indicators of Cardiac Exposure Following Breast Radiotherapy
Radiotherapy plays an integral role in breast cancer therapy. Multiple randomized studies have demonstrated decreased local-regional recurrence rates and decreased breast-cancer mortality.
- Trial name
- NCT02496260
- Testing
- Research Cardiac MRI, Biomarkers
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Henry Ford Health System
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