Clinical trials: Magnetic Resonance Imaging (MRI)
Chronic Liver Disease
Delta Radiomics for Liver Function Evaluation
To evaluate the feasibility and efficacy of delta radiomics-derived index based on Gd-EOB-DTPA enhanced MRI as a new imaging biomarker for the quantitative assessment of liver function.
- Trial name
- NCT05296434
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Seizure Disorder, Seizure Disorder, Post Traumatic
Neuroimaging Biomarker for Seizures
This multi-site study will examine patients with epilepsy (ES) following head injury [i.e., posttraumatic epilepsy (PTE)] and posttraumatic psychogenic Non-epileptic seizures (PNES) and will compare them to patients with…
- Conditions
- Seizure Disorder, Seizure Disorder, Post Traumatic, Traumatic Brain Injury, Non-Epileptic Seizure
- Trial name
- NIBMSZS (NCT03441867)
- Testing
- Cognitive Behavioral Therapy for Seizures, Standard Medical Care
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Providence VA Medical Center
Writer's Cramp
Video-supervised Motor and Awareness Training in Writer's Cramp
Writer's cramp is the most common task-specific dystonia. It is characterized by involuntary co-contraction of antagonistic muscles during writing. This disabling condition may force patients to give up their occupation.
- Trial name
- NCT04611009
- Testing
- motor training, mindfulness exercises
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- University Hospital Schleswig-Holstein
Cirrhosis of Liver
Gadoxetic Acid-MRI Versus Ultrasonography for the Surveillance of Hepatocellular Carcinoma in High-risk Patients
Current practice guidelines recommend surveillance for hepatocellular carcinoma (HCC) in liver cirrhosis patients with ultrasonography (USG) every 6 months.
- Trial name
- PRIUS (NCT01446666)
- Where
- South Korea
- Volunteers
- 423 people
- Sponsor
- Asan Medical Center
Heart Failure and Reduced Ejection Fraction, Functional Mitral Regurgitation
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
This is a multi-center, prospective, observational study designed to evaluate the impact of LV myocardial fibrosis extent assessed by CMR on LV reverse remodeling and clinical outcomes post TEER.
- Trial name
- SMARTER-CMR (NCT07131631)
- Testing
- Cardiac MRI
- Where
- 6 sites in United States, Italy
- Volunteers
- 125 people
- Sponsor
- Minneapolis Heart Institute Foundation
Cardiac Arrhythmia
Use of "iSuite" During CMR-guided Electrophysiological Procedures
The perpuse of this study is to investigate the feasibility of the Philips interventional MRI suite "iSuite" to create an electroanatomical map of the heart based on which the real-time location of the catheters can be correctly…
- Trial name
- NCT04727645
- Testing
- Philips interventional MRI suite (Philips Healthcare, Best, the Netherlands)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Bronchiolitis Obliterans
Hyperpolarized 129Xe MRI for the Assessment of BOS With Late Onset LONIPC
The development of bronchiolitis obliterans syndrome (BOS) and other late onset non-infectious pulmonary complications (LONIPCs) following hematopoietic stem cell transplantation (HSCT) is associated with a significantly worse…
- Trial name
- BOS-MRI (NCT04029636)
- Testing
- Inhaled Hyperpolarized Xenon-129
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Hamilton Health Sciences Corporation
Twin Pregnancy With Antenatal Problem
Diffusion Weighted Magnetic Resonance Imaging of Brain in Monochorionic Twin Pregnancies With Demise of One Fetus
Diffusion weighted imaging (DWI) can reflect the microstructure and pathological changes of tissue, and diffusion tensor imaging (DTI) can quantitatively evaluate the fine structure of white matter in brain.
- Trial name
- NCT04966039
- Testing
- No intervention.
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Head and Neck Neoplasms
The EMINENCE Study - PET/MR Imaging of Head Neck Cancer
Head and neck cancers (HNC) often receive radiotherapy as part of their treatment. However, unacceptable failure rates and severe side effects remain a challenge.
- Trial name
- EMINENCE (NCT04612075)
- Testing
- FDG-PET/MRI
- Where
- 2 sites in Norway
- Volunteers
- 390 people
- Sponsor
- Norwegian University of Science and Technology
Atherosclerosis
Oxford Niaspan Study: Effects of Niaspan on Atherosclerosis and Endothelial Function
AIM 1 will test the hypothesis that elevation of high-density lipoprotein (HDL) through treatment with Niaspan will accelerate the regression of atherosclerotic plaque in patients with established atherosclerosis.
- Trial name
- NCT00232531
- Testing
- Niaspan
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Oxford
Cerebrovascular Circulation
MRI Biomarkers and Exercise
The overall goal of observational study is to examine the age-related and habitual exercise training status-related differences in structural and functional changes in the human brain, detected by magnetic resonance (MR) imaging.
- Trial name
- NCT02729428
- Testing
- MRI
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
The purpose of this research is to understand how to apply cardiac magnetic resonance imaging (CMR) to women with small artery heart disease by looking at the CMRs of women without heart disease.
- Trial name
- NCT00573339
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Acute Myocardial Infarction
Ischemic Time and Extent of Myocardial Infarction (MI) With Cardiac Magnetic Resonance Imaging (CMRI) in Patients With ST Elevation Myocardial Infarction (STEMI) and Primary Percutaneous Coronary Intervention (PCI) Study
This study will assess relationship between ischemic time and the extent of myocardial infarction with cardiac magnetic resonance image in patients with STEMI (ST elevation myocardial infarction) and primary percutaneous coronary…
- Trial name
- ITEMMRI (NCT01401881)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medstar Health Research Institute
Breast Carcinoma; Magnetic Resonance Imaging;OGSE
Study on the Correlation Between the Quantitative Parameters of Mr Mean Cell Size Imaging and the Histopathological Characteristics of Breast Cancer
Patients with breast masses and suspected breast malignancies by ultrasound / mammography were prospectively included. After routine MRI scanning, all patients underwent average cell size imaging sequence scanning, and finally…
- Trial name
- OGSE (NCT05373628)
- Testing
- Gradient and pulse imaging
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cerebrovascular Disorder, Healthy
Magnetic Resonance Imaging Studies of Motor and Thought Processes
Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation).
- Conditions
- Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease
- Trial name
- NCT00001361
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pancreas Cancer, Lung Cancer
Stereotactic Magnetic Resonance Guided Radiation Therapy
This is a master prospective Phase I-II trial evaluating feasibility and efficacy of stereotactic magnetic resonance (MR) guided adaptive radiation therapy (SMART) in patients with cancer.
- Conditions
- Pancreas Cancer, Lung Cancer, Renal Cancer, Adrenal Metastases
- Trial name
- NCT04115254
- Testing
- MR-guided Linac
- Where
- 2 sites in United States
- Volunteers
- 397 people
- Sponsor
- Dana-Farber Cancer Institute
Cardiac Disease
Safety and Clinical Outcomes of Magnetic Resonance Imaging in Patients With Cardiac Implantable Electrical Devices
This protocol outlines a prospective study evaluating safety and clinical outcomes of magnetic resonance imaging (MRI) examinations performed on patients with cardiac implantable electrical devices (CIEDs) including pacemakers…
- Trial name
- BIDMC-MRI (NCT03016429)
- Where
- United States
- Volunteers
- 1,169 people
- Sponsor
- Beth Israel Deaconess Medical Center
Painful Diabetic Neuropathy
Functional Magnetic Resonance Imaging of Brain Activity in Patients With Painful Diabetic Neuropathy
Patients with painful diabetic neuropathy (PDN) often combine with anxiety and depression. However, the pathogenesis of PDN is unclear, especially the mechanism associated with central nervous system.
- Trial name
- NCT03700502
- Testing
- resting-state functional Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Myocardial Ischemia
Electromechanical Mapping to Evaluate Heart Muscle
Patients with narrowed heart arteries who undergo coronary angiography (imaging of the heart's blood vessels) may participate in this "heart mapping" study designed to gain information about the condition of different areas of…
- Trial name
- NCT00001895
- Testing
- FDG, NH(3)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Reproducibility of Results
Reproducibility of Brain MRI
The aim of this study is to assess the reproducibility over time of functional and structural magnetic resonance imaging, as well as specific biomarkers in plasma in healthy volunteers before and after a two-hour rest.
- Trial name
- DANA0 (NCT03876236)
- Where
- 2 sites in Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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