Clinical trials: Magnetic Resonance Imaging (MRI)
Bladder Cancer
Multiparametric Magnetic Resonance Imaging (MRI) to Improve Bladder Cancer Staging and Treatment Decision-making
The therapeutic approach to bladder cancer is strongly dependent on tumor stage and grade. Patients with non-muscle-invasive tumors (NMIBC) are usually treated with surgical resection of the tumor alone, whereas patients with…
- Trial name
- SBCT (NCT04533672)
- Testing
- MRI Sequences
- Where
- Switzerland
- Volunteers
- 186 people
- Sponsor
- University of Zurich
Styloid-Stylohoid Syndrome, Temporomandibular Disorder
Evaluation of Styloid Chain Calcification to the Patient With the Temporomandibular Joint Disorder
The aim of the study was to evaluate any relation between elongated styloid process (ESP) and type of Temporomandibular Joint Disorders (TMD).
- Trial name
- NCT04280107
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Nuh Naci Yazgan University
Breast Implantation
Breast Fat Grafting Augmentation in Chinese Women
A total of 38 Chinese healthy women underwent autologous fat grafting for cosmetic breast augmentation. Breast volumes were measured by magnetic resonance imaging preoperatively and 1 year after the procedure.
- Trial name
- NCT02551939
- Testing
- Autologous Fat Grafting
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Multiple Sclerosis
MRI Study of the Mechanisms Underlying Irreversible Disability in Multiple Sclerosis
Multiple sclerosis (MS) is the first non-traumatic cause of disability in young people, responsible for physical but also cognitive deficits.
- Trial name
- SEP-MRI (NCT03356366)
- Testing
- MRI 3T, MRI 1,5T, MRI 7T
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Prostate Cancer, Head and Neck Cancer
Predictors of Normal Tissue Response From the Microenvironment in Radiotherapy for Prostate and Head-and-neck Cancer
The main idea behind MICRO-LEARNER is to provide new insights about the response of healthy tissues to radiation by using information from the micro-environment obtained by biological measurements and imaging.
- Trial name
- MICROLEARNER (NCT03294122)
- Testing
- External beam radiotherapy for prostate cancer, External beam radiotherapy for head and neck cancer
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
IUGR, Gestational Diabetes
PED NEONAT 20-000599 Fetal Body Composition
Obesity is an ongoing public health problem that is difficult to treat. There is evidence that obesity has fetal origins. Body composition, including visceral, subcutaneous, brown, and hepatic fat have been found to be important…
- Conditions
- IUGR, Gestational Diabetes, Pregnancy Related
- Trial name
- NCT04508751
- Testing
- 3T "Free-Breathing" Fetal Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Glioblastoma, Glioblastoma Multiforme
Biologically-based Target Volumes to Treat Newly Diagnosed Glioblastoma
This clinical trial increases radiation to areas of the brain considered to be at risk for cancer. The at-risk areas are identified by a biological MRI scan.
- Trial name
- NCT03506139
- Testing
- External beam radiation therapy
- Where
- United States
- Sponsor
- John M. Buatti
Anorexia Nervosa (DSM-IV Revised Criteria)
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive Disorder
The goal of this clinical trial is to evaluate the safety and initial clinical effectiveness of MRI-guided focused ultrasound (MRgFUS) thermal ablation (capsulotomy) in patients with treatment-refractory anorexia nervosa (AN) and…
- Trial name
- NCT07113665
- Testing
- ExAblate Neuro 4000
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prolapse
Clinical and Dynamic Floor MRI Evaluation Before and After Prolapse Surgery
Pelvic organ prolapsed, associated with defecation disorders and urinary tracts symptoms are common and affect up to 25% of the population, mostly parous women.
- Trial name
- NCT03400007
- Testing
- Dynamic floor magnetic resonance imaging, Colpocystodefecography
- Where
- 2 sites in Belgium
- Volunteers
- 34 people
- Sponsor
- Tatiana Besse-Hammer
Magnetic Resonance Angiography, Hemodialysis
3D Time-of-Flight Magnetic Resonance Angiography in Hemodialysis Patients With Arteriovenous Fistula
This study is aimed to assess the value of three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) in hemodialysis patients with occlusive disease in arteriovenous fistula (AVF).
- Conditions
- Magnetic Resonance Angiography, Hemodialysis, Arteriovenous Fistula Stenosis
- Trial name
- NCT04312711
- Testing
- 3D-TOF-MRA
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Normal Physiology
Perception, Sensation, Cognition and Action in Humans
Background: When people see and hear, the brain changes signals from the eyes and ears into perceptions and thoughts. No one fully understands how this happens.
- Trial name
- NCT03407066
- Where
- 2 sites in United States
- Volunteers
- 10,200 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Solid Tumors, ER/PR Positive Breast Cancer
MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment
This is a Phase I study to understand the biodistribution of MM-398 and to determine the feasibility of using Ferumoxytol as a tumor imaging agent.
- Conditions
- Solid Tumors, ER/PR Positive Breast Cancer, Triple Negative Breast Cancer, Metastatic Breast Cancer With Active Brain Metastasis
- Trial name
- NCT01770353
- Testing
- Ferumoxytol, MM-398
- Where
- 7 sites in United States
- Volunteers
- 45 people
- Sponsor
- Ipsen
Spondyloarthritis
Etanercept (Enbrel) in Undifferentiated Spondyloarthritis
The study has the aim to investigate the efficacy and safety of etanercept in patients with active undifferentiated spondyloarthritis (uSpA) over the period of 520 weeks.
- Trial name
- Enbrel_uSpA-2 (NCT01289730)
- Testing
- Etanercept
- Where
- 2 sites in Germany
- Volunteers
- 8 people
- Sponsor
- Charite University, Berlin, Germany
Epilepsy
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
Background: The blood-brain barrier separates the brain from the rest of the body. Epilepsy is a neurological disease that causes seizures. It can affect this barrier.
- Trial name
- NCT02531880
- Testing
- Mangafodipir, Gadolinium
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Type 1 Diabetes Mellitis, Cognition
Glycemic Control, Brain Structure and Cognition in Youth With Type 1 Diabetes (T1DM)
LO5 study: The investigators are inviting a new group of youth (ages 7-16) who have been recently diagnosed with type 1 diabetes and their non-diabetic siblings.
- Trial name
- LO5/HY5 (NCT00879203)
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stress, Healthy Volunteers
Brain Responses to Short-Chain Fatty Acid Intervention
A randomized, triple-blind, placebo-controlled study on the effect of colon-delivered short-chain fatty acids (SCFAs) on neural responses to stress and neuroepigenetics.
- Trial name
- MoodBugs HDAC (NCT06546683)
- Testing
- Short-Chain Fatty Acids
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy, Covert Consciousness
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
This research is studying whether mental functions take place during different levels of anesthesia, using a commonly used drug (either dexmedetomidine [with propofol in some participants] or ketamine), which shows areas in the…
- Trial name
- NCT07705022
- Testing
- Dexmedetomidine (+propofol as indicated), Ketamine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Meniscus Lesion
Sterile Allogeneic Spongioflex® Allograft as Partial Meniscal Replacement After Incomplete Meniscal Loss
The goal of this clinical trial is to learn if partial meniscal replacement can prevent or postpone total meniscal replacement, in adult patients (female/male) with partial meniscal loss.
- Trial name
- NCT06376422
- Testing
- Spongioflex®, non-operated
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Sven Behrendt
Stable Coronary Artery Disease, Cardiac Magnetic Resonance Imaging
Magnetic Resonance Adenosine Perfusion Imaging as Gatekeeper of Invasive Coronary Intervention
Current guidelines for the diagnosis and management of patients with stable coronary artery disease (CAD) strongly support the performance of non-invasive imaging techniques for the detection of myocardial ischemia prior to…
- Conditions
- Stable Coronary Artery Disease, Cardiac Magnetic Resonance Imaging, Coronary Angiography, Myocardial Revascularization
- Trial name
- MAGnet (NCT02580851)
- Testing
- diagnostic test - cardiac magnetic resonance imaging, diagnostic test - coronary angiography
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Ulm
Cerebrovascular Accident
Evaluating the Remote Effects of Stroke With MRI and PET Scans
Patients with stroke sometimes have a condition called diaschisis, a loss of function in a part of the brain located some distance from the original stroke-injury site. Doctors do not know why this happens.
- Trial name
- NCT00063180
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
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