Clinical trials: Magnetic Resonance Imaging Contrast Agents
Liver Tumors
Contrast Enhanced (CE) Ultrasound and CE Computed Tomography or CE Magnetic Resonance Imaging in Liver Masses
This comparison study is performed to show equivalence of CEUS with CECT or CEMR to diagnose noninvasively focal liver masses. This is a multi-center prospective cohort study of 250 subjects, which will be performed at four…
- Trial name
- NCT00828607
- Where
- 4 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Foothills Medical Centre
Contrast Enhanced Images vs. Non-contrast Images, Gadopiclinol Enhanced Images vs. Gadobutrol Enhanced Images
Gadopiclenol vs. Gadobutrol for Dynamic Contrast-Enhanced Pituitary MRI (Magnetic Resonance Imaging)
This study will evaluate the efficacy and safety of Gadopiclenol, an FDA-approved contrast agent, for visualizing pituitary lesions on MR images by comparing with the comparator, Gadobutrol, a clinically widely used contrast…
- Trial name
- MRI (NCT06846853)
- Testing
- Gadopiclenol, Gadobutrol (Gadavist, BAY86-4875)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- UConn Health
Contrast Enhancement in Magnetic Resonance Imaging
A Study to Evaluate the Pharmacokinetics (How it Moves Into, Through and Out From the Body) of a New Gadolinium-based Contrast Agent (GBCA) After Injection and How Safe it is in Participants With Normal and Impaired Renal Function
Researchers in this study want to learn how a new contrast agent for magnetic resonance imaging (MRI) called BAY1747846 moves into, through and out of the body (pharmacokinetics) after injection in participants with normal and…
- Trial name
- NCT05061979
- Testing
- BAY1747846
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Renal Dysfunction
Evaluation of Gadoterate in Patients With Renal Dysfunction
This study is for individuals with decreased kidney function whose doctor has ordered Magnetic Resonance Imaging (MRI). Because kidney function is decreased, these patients usually do not receive the intravenous contrast material…
- Trial name
- NCT02382380
- Testing
- Gadoterate, No Gadoterate
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Loyola University
Cystic Fibrosis
MR Imaging of Lung in the Follow-up Assessment of Cystic Fibrosis
The aim of the study is to assess the diagnostic sensitivity of MRI to detect changes in Helbich-Bhalla scoring over time in patients with cystic fibrosis
- Trial name
- CFMR-lung (NCT03357562)
- Testing
- lung MRI
- Where
- 11 sites in France
- Volunteers
- 212 people
- Sponsor
- University Hospital, Bordeaux
Magnetic Resonance Imaging, Image Enhancement
Drug Use Investigation of Gadovist.
The objectives of this study are to investigate the safety and effectiveness of Gadovist.
- Trial name
- NCT02540967
- Testing
- Gadobutrol (Gadavist/Gadovist, BAY86-4875)
- Where
- Japan
- Volunteers
- 3,357 people
- Sponsor
- Bayer
Atherosclerosis, Peripheral Artery Disease
Imaging of Totally Blocked Arteries
This study will test how well a new contrast agent (dye) used in magnetic resonance imaging (MRI) can help visualize totally blocked arteries that normally supply blood to the neck, arms or legs.
- Conditions
- Atherosclerosis, Peripheral Artery Disease, Intermittent Claudication, Chronic Total Aterial Occlusion
- Trial name
- NCT00459446
- Testing
- MS-325 Injection (Gadofosveset Trisodium)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ovarian Neoplasms
Magnetic Resonance Imaging for Lymph Node Staging in Ovarian Cancer
Advanced epithelial ovarian cancer has high morbidity and mortality. Patients presenting with advanced stage ovarian cancer often have cancer spread to regional lymph nodes.
- Trial name
- MILO (NCT02243059)
- Testing
- Gadofosveset trisodium (Ablavar™ ), MRI
- Where
- Netherlands
- Sponsor
- Maastricht University Medical Center
Kidney Failure, Acute
Non-invasive Evaluation of the Predictive Value of CEUS and SWE in ACLF, Renal Failure and Hepatorenal Syndrome
Evaluation of non-invasive prognostic parameters in patients developing ACLF and renal failure in patients receiving and not receiving transjugular intrahepatic portosystemic shunt (TIPS).
- Trial name
- NECTAR (NCT04446858)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Bonn
Glaucoma
Ocular Blood Flow Assessment in Glaucoma
Background : Glaucoma is a common disease, potentially blinding, characterized by progressive damage to the optic nerve. If the intraocular pressure is the most known risk factor, however, there are cases of glaucoma scalable…
- Trial name
- OBAMAg (NCT02178085)
- Testing
- Flow imaging
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Dilated Cardiomyopathy, Thrombosis Cardiac
Intraventricular Stasis In Cardiovascular Disease
This study is designed to quantify the ventricular stasis in patients with different forms of cardiomyopathy and at risk of stroke (ischemic, non-ischemic dilated cardiomyopathy and hypertrophic cardiomyopathy) by post-processing…
- Conditions
- Dilated Cardiomyopathy, Thrombosis Cardiac, Stroke, Hypertrophic Cardiomyopathy
- Trial name
- ISBIFLOW (NCT04649034)
- Testing
- Doppler echocardiogram exam, Cardiac magnetic resonance, Brain magnetic resonance
- Where
- 3 sites in Spain
- Volunteers
- 258 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Known or Suspected Focal Liver Lesions
Efficacy and Safety of Primovist in Chinese Patients
Participants who had been diagnosed or suspected by doctors to have focal liver lesions that need further evaluation in order to make an accurate diagnosis.
- Trial name
- NCT00526188
- Testing
- Gadoxetic Acid Disodium (Primovist, BAY86-4873)
- Where
- 6 sites in China
- Volunteers
- 234 people
- Sponsor
- Bayer
Microvascular Coronary Artery Disease, Heart Failure With Reduced Ejection Fraction
CMR Assessment of Cardiac Microvascular Dysfunction in Patients With HFpEF
Heart failure with preserved ejection fraction (HFpEF) causes hospitalizations, premature mortality and high health care costs. This is also due to poor understanding of HFpEF pathogenesis and, thus, lack of specific therapies.
- Trial name
- MAPPED (NCT06316661)
- Testing
- stress perfusion cardiac magnetic resonance, cardiopulmonary exercise test
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Non-Small Cell Lung Cancer, Brain Metastases
Retrospective Multicenter Study of Patient-level T1CE/FLAIR MRI Deep Learning to Predict EGFR/ALK Driver Status in NSCLC Brain Metastases With External Validation and Survival Analysis
This retrospective multicenter observational study aims to develop and externally validate a noninvasive deep learning model based on routine brain MRI to identify actionable driver alterations in patients with non-small cell…
- Trial name
- DL-DriverBM (NCT07373951)
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Ming Yang
Low-grade Glioma
Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas
Retrospective longitudinal follow-up in patients with diffuse low-grade glioma with multimodal MRI assessment
- Trial name
- SPECIFY (NCT04346472)
- Testing
- Repeated Measurements of the relative regional cerebral blood volume
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Glioblastoma
Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Glioblastoma
MRI including ASL will be performed before, during and after the treatment, in a total of 7 MRI sessions until 8 months after the first session.
- Trial name
- NCT03922984
- Testing
- MRI with Arterial Spin Labeling (ASL)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Kidney Diseases
Establishing a New Ultrasound Technique to Improve Assessment of Chronic Kidney Disease.
Blood flow to the kidneys is important in the development of kidney diseases. Currently we do not have ways of measuring and monitoring kidney blood flow for patients in real-time.
- Trial name
- NCT06159439
- Testing
- Contrast enhanced ultrasound scan, MRI scan
- Volunteers
- 10 people
- Sponsor
- University of Nottingham
Cerebral Arterial Diseases
Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)
The study will evaluate the efficacy and safety of Dotarem enhanced MRA in patients suffering from carotid or vertebral arterial disease.
- Trial name
- NCT01010932
- Testing
- Dotarem, TOF MRA
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Guerbet
IC - Interstitial Cystitis
Phenotyping Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by Intravesical Contrast Enhanced - Magnetic Resonance Imaging (ICE-MRI) Bladder Permeability Assay
Each participant will be asked to participate in this research study which distinguishes different types of Interstitial Cystitis/Bladder Pain Syndrome. Research studies include only people who wish to participate.
- Trial name
- NCT05811377
- Testing
- Ferumoxytol, Gadobutrol
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Christopher J Chermansky, MD
Breast Neoplasms
Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging to Assess Tumor-Associated Vasculature in Patients With Metastatic Breast Cancer
This study will examine a non-invasive method to assess vasculature, that is, the development of a blood supply necessary to the growth of tumors.
- Trial name
- NCT00071357
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)