Clinical trials: Magnetic Resonance Imaging Contrast Agents
Central Nervous System Pathology
Study to Find the Appropriate Dose of a New Gadolinium-based Contrast Agent (GBCA) for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Brain and/or Spinal Cord Conditions
Researchers in this study want to find the appropriate dose of drug BAY1747846 for adults undergoing MRI for known or highly suspected brain and/or spinal cord conditions so that the image quality is similar to that of drug…
- Trial name
- NCT04307186
- Testing
- Gadoquatrane (BAY1747846), Gadobutrol (Gadovist/Gadavist)
- Where
- 17 sites in United States, Bulgaria and 2 more
- Volunteers
- 57 people
- Sponsor
- Bayer
Valvular Heart Disease (Aortic and Mitral Valves)
Phase Contrast in Valvular Heart Disease
The ability to quantify flow directly using through-plane phase contrast velocity mapping is a unique advantage of cardiovascular magnetic resonance and does not rely on the calculation from complex equations as echocardiography.
- Trial name
- NCT03669666
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Assiut University
Hepatocellular Carcinoma (HCC)
Comparing Diagnostic Accuracy for Liver Tumours Between the Combination of CEUS and CEMRI Versus CECT and CEMRI
Hepatocellular carcinoma (HCC) is unique regarding diagnosis because the clinical diagnosis without pathology proof is accepted.
- Trial name
- NCT03267290
- Testing
- Sonazoid- CEUS, CEMRI, CECT
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Carcinoma, Hepatocellular
3T MRI to Predict TACE Response of HCC
This study is a prospective clinical study using DCE-MRI, DWI and MRS in 3T scanner to evaluate tumors in patients with unresectable HCC after TACE. A total of 100 subjects will be recruited.
- Trial name
- NCT02070822
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Liver Metastasis, Liver Mass
Evaluation of Suspected Liver Pathology in Patients With Contraindications for Contrast Enhanced CT and/or MRI
Patients with renal failure or other reason for contraindication for contrast enhanced computed tomography (CECT) or contrast enhanced magnetic resonance imaging (CEMRI) with suspected liver pathology will be evaluated with…
- Trial name
- NCT02651090
- Testing
- Sonazoid
- Sponsor
- Northeastern Ohio Radiology Research and Education Fund
Carotid Artery Stenosis, Atherosclerosis
Contrast-enhanced Ultrasound (CE-US) and Magnetic Resonance Imaging (MRI): Evaluating Plaque Neovascularisation
The first goal of this study is to investigate whether CE-US is able to accurately identify and quantify neovascularisation in carotid artery plaques.
- Trial name
- NCT00677963
- Testing
- sulphur hexafluoride, gadopentate dimeglumine
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Maastricht University Medical Center
Cancer of the Prostate
Comparison Of DIR-MRI And DCE-MRI In Detection Of Prostate Cancer: A Pilot Study
This is a pilot study taking place at University Hospitals of North Midlands NHS Trust. Patients referred for MRI for possible prostate cancer will be invited to take part in the study.
- Trial name
- DIRMP (NCT02939456)
- Testing
- Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Magnetic Resonance Imaging
Evaluation of 4D Magnetic Resonance Flow Sequence at Hepatic Level
The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency
- Trial name
- HEPAFLUX (NCT02821078)
- Testing
- 4D flow imaging sequence
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Coronary Artery Disease, Stable Angina
Detection of Coronary Vulnerable Plaque With Contrast-enhanced Magnetic Resonance Imaging
MRI has the ability to visualize the arterial vessel wall. Wall thickening and atherosclerotic plaque components can be visualized in the carotid arteries and the aorta.
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina
- Trial name
- T9M (NCT00984776)
- Testing
- Contrast enhanced MRI with Gadofosveset
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Optic Neuritis, Multiple Sclerosis
The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CIS
Disruption of the blood brain barrier (BBB) is associated with inflammatory conditions of the central nervous system (CNS). This clinical trial aims to investigate whether following a gluten-free diet (GFD) for six months can…
- Conditions
- Optic Neuritis, Multiple Sclerosis, Clinically Isolated Syndrome
- Trial name
- NCT03451955
- Testing
- Gluten-free diet
- Where
- 2 sites in Denmark
- Volunteers
- 103 people
- Sponsor
- University of Copenhagen
Osteosarcoma
Diffusion Study on Patients With Osteosarcoma
The aim of the study is to assess the accuracy of dynamic contrast enhanced and diffusion-weighted MR Imaging in evaluating response to chemotherapy in osteosarcoma.
- Trial name
- NCT01615640
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Klinikum Stuttgart
Renal Cell Carcinoma
Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Metastatic Renal Cell Carcinoma
Magnetic Resonance Imaging (MRI) including Arterial Spin Labeling (ASL) will be performed before, during, and after the treatment, in a total of up to 6 MRI sessions until 7 months after the first session, or when progression is…
- Trial name
- NCT04831138
- Testing
- MRI with ASL, ASL-MRI
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Glioblastoma Multiforme, Gliosarcoma
Multi-site Validation and Application of a Consensus DSC-MRI Protocol
This clinical trial is to validate and demonstrate the clinical usefulness of a protocol for Magnetic Resonance Imaging (MRI) in people with high grade glioma brain tumors.
- Trial name
- NCT03401866
- Testing
- DSC-MRI
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix