Clinical trials: Maintenance Hemodialysis
Renal Failure Chronic Requiring Hemodialysis, Poor Quality Sleep
BIA-Guided Dry Weight Assessment on Sleep Quality in Chronic Hemodialysis Patients
Based on many previous data proving hypervolemia in chronic hemodialysis patients could lead to sleep apnea and poor sleep quality.
- Trial name
- BEDTIME (NCT02825589)
- Testing
- BIA
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
CKD (Chronic Kidney Disease) Stage 5D, Hemodialysis
Effect of Kidney Replacement Therapy with Polymethylmethacrylate Membranes on Pruritus-related Quality of Life in Patients Receiving Maintenance Haemodialysis
This randomized controlled trial aims to evaluate the effect of polymethylmethacrylate dialysis membranes use on the intensity of pruritus in patients with CKD stage 5D receiving maintenance hemodialysis.
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D, Hemodialysis, Pruritis
- Trial name
- NCT06671535
- Testing
- Polymethylmethacrylate membrane, polysulfone membranes
- Where
- Russia
- Volunteers
- 62 people
- Sponsor
- Saint Petersburg State University, Russia
End Stage Renal Failure, Hemodialysis, Restless Leg Syndrome (RLS)
Efficacy and Safety of Super High-Flux Hemodialysis in Maintenance Dialysis Patients. SHINE-RLS (Super High-flux Dialysis Improves Neuro-symptoms and Efficacy in Restless Legs Syndrome)
Patients with end-stage kidney disease (ESKD) rely on maintenance hemodialysis. While high-flux hemodialysis improves small solute clearance, its removal of middle-molecule uremic toxins (e.g., α1-microglobulin [α1-MG]) remains…
- Trial name
- SHINE-RLS (NCT07794826)
- Testing
- Super High-Flux HD
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Far Eastern Memorial Hospital
ESRD (End-Stage Renal Disease), Maintenance Hemodialysis
Efficacy of pHA130 Hemoadsorption on Protein-Bound Uremic Toxins and Quality of Life in Kidney Failure
Patients on maintenance hemodialysis (MHD) face a high risk of cardiovascular mortality and reduced quality of life. Conventional high-flux hemodialysis (HD) is the standard of care but has limited efficacy in clearing…
- Trial name
- PHOENIX (NCT07656168)
- Testing
- pHA130 Hemoadsorption Cartridge, High-flux Hemodialyzer
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
Chronic Renal Failure Requiring Hemodialysis
A Phase 3, Long-Term Safety Study of Intravenous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of the study is to determine the long-term safety in treatment-emergent adverse events (TEAEs) of intravenous (IV) administration of Epoetin Hospira for maintenance of target hemoglobin (Hgb) levels in patients…
- Trial name
- AiME - 03 (NCT01628107)
- Testing
- Epoetin Hospira
- Where
- 110 sites in United States, Puerto Rico
- Volunteers
- 406 people
- Sponsor
- Pfizer
Coronary Artery Calcification
The Effects and Safety of Low Calcium Dialysis on Coronary Artery Calcification in Maintenance Hemodialysis Patients
This study aim to observe the preventive effect and the long term safety of low calcium dialysis on coronary artery calcification in Maintenance hemodialysis (MHD) patients.
- Trial name
- NCT02498457
- Testing
- low calcium dialysis
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Hypertension on Chronic Maintenance Hemodialysis
The Pharmacokinetics of Nifedipine Controlled Release Tablets in Hypertensive Patients on Hemodialysis
This is a prospective, open, non-randomized, non-controlled study. 20 patients with hypertension on chronic maintenance hemodialysis will be enrolled in the study.
- Trial name
- PICASSO (NCT01021501)
- Testing
- nifedipine controlled release tablets
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangzhou First People's Hospital
Hemodialysis Patients
The Effect of Horticultural Therapy on Stress, Well-Being, and Care Burden in Hemodialysis Caregivers
This research is a randomized controlled single-blind experimental study aiming to evaluate the effect of horticultural therapy on stress, well-being, and caregiver burden among caregivers of hemodialysis patients.
- Trial name
- NCT07188792
- Testing
- HORTICULTURAL THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
Hemodialysis, Hemodialysis Patient
Calm in the Storm: Reducing Night Pain and Enhancing Sleep Through a Nurse- Led Benson's Relaxation Intervention in Hemodialysis Patients
Patients undergoing maintenance hemodialysis (HD) frequently experience persistent pain and sleep disturbances which negatively influence their quality of life and overall wellbeing.
- Trial name
- NCT07814469
- Testing
- Benson's Relaxation Intervention
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Hemodialysis, Cerebral Blood Flow
Association Between Cerebral Blood Flow Change and Cognitive Function in Hemodialysis Patients
The prevalence of cognitive impairment in maintenance hemodialysis (MHD) patients is 3 to 5 times higher than that in ordinary people, so it is essential to find the associated risk factors in this population.
- Conditions
- Hemodialysis, Cerebral Blood Flow, Cognitive Function, Magnetic Resonance Imaging
- Trial name
- NCT05555836
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Patients on Stable Chronic Maintenance Dialysis Who Are Receiving Hemodialysis Therapy, Pharmacodynamics of ASP7991
Examination of Plasma Concentrations and Safety in Chronic Kidney Disease Patients Undergoing Hemodialysis
This study is to assess the safety, tolerability, plasma concentration and pharmacodynamics of ASP7991 after oral administration to patients with chronic kidney disease undergoing hemodialysis.
- Conditions
- Patients on Stable Chronic Maintenance Dialysis Who Are Receiving Hemodialysis Therapy, Pharmacodynamics of ASP7991, Pharmacokinetics of ASP7991
- Trial name
- NCT01872026
- Testing
- ASP7991
- Where
- Japan
- Volunteers
- 14 people
- Sponsor
- Astellas Pharma Inc
Kidney Failure, Chronic, Exercise
The Effect of Intradialytic Combined Exercise on Physical Outcomes in End-Stage Renal Disease Patients
Hemodialysis (HD) is an important and commonly used renal replacement therapy (RRT) for End-Stage Renal Disease (ESRD) patients worldwide.
- Conditions
- Kidney Failure, Chronic, Exercise, Physical Fitness
- Trial name
- NCT04124549
- Testing
- Intradialytic Combined Exercise
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Xi'an Jiaotong University
Nursing, Hemodialysis Patient
THE EFFECTS OF CIRCADIAN RHYTHM-BASED PROGRESSIVE RELAXATION EXERCISES IN HEMODIALYSIS PATIENTS
The aim of this study is to determine the effect of Progressive Relaxation Exercise (PGE) applied according to the circadian rhythms of hemodialysis (HD) patients on symptom management, sleep quality, comfort and mental…
- Conditions
- Nursing, Hemodialysis Patient, Circadian Rhythm, Relaxation Exercise
- Trial name
- NCT07499297
- Testing
- Progressive Relaxation Exercises
- Volunteers
- 75 people
- Sponsor
- Karamanoğlu Mehmetbey University
Chronic Renal Failure, Chronic Kidney Disease
Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
The purpose of this study was to evaluate the safety and efficacy of peginesatide in the maintenance treatment of anemia in participants on dialysis.
- Conditions
- Chronic Renal Failure, Chronic Kidney Disease, Anemia
- Trial name
- EMERALD 2 (NCT00597584)
- Testing
- peginesatide, Epoetin alfa or Epoetin beta
- Where
- 84 sites in United States, Bulgaria and 7 more
- Volunteers
- 823 people
- Sponsor
- Affymax
Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis
Study of MT1013 Injection for the Treatment of Secondary Hyperparathyroidism (SHPT) Patients With Chronic Kidney Disease Undergoing Maintenance Dialysis
This is a multi-center, open, single-arm phase IIb clinical study comprising 2 parts, which Part A will enroll about 110 subjects, and Part B will enroll about 190 subjects to investigate long-term efficacy and safety of MT1013…
- Trial name
- NCT06976177
- Testing
- MT1013
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Shaanxi Micot Pharmaceutical Technology Co., Ltd.
Chronic Kidney Disease
Study of Phosphate Levels in Patients With Chronic Kidney Disease
The purpose of this study is to investigate the ability of different doses of PA21 to lower serum phosphate levels, in patients with chronic kidney disease on maintenance hemodialysis.
- Trial name
- PA21 (NCT00824460)
- Testing
- 1.25 g PA21 (250 mg iron), 5.0 g PA21 (1,000 mg iron), 7.5 g PA21 (1,500 mg iron)
- Where
- 60 sites in United States, Bulgaria and 7 more
- Volunteers
- 154 people
- Sponsor
- Vifor Pharma
Renal Dialysis
The Effect of Active Exercise on Maintenance Haemodialysis Patients
The goal of this clinical trial is to discuss the effects of physical activity on nutrition, inflammation, muscle metabolism, and the occurrence of cardiovascular and cerebrovascular events in patients with maintenance…
- Trial name
- NCT06568835
- Testing
- exercise
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Yunfeng Xia
End Stage Renal Disease
Effects of Hemodialysis Plus Hemoperfusion in Maintenance Hemodialysis Patients: A Clinical Study
This multi-center, open-label, randomized, parallel controlled trial aims to investigate the efficacy of hemoperfusion (HP) in combination with hemodialysis (HD) by assessing blood β2-microglobulin (β2-MG), parathyroid hormone…
- Trial name
- NCT05639010
- Testing
- regular hemodialysis, hemoperfusion combined with hemodialysis
- Where
- China
- Volunteers
- 410 people
- Sponsor
- Changhai Hospital
Hemodialysis Patients
Clinical Study of R744 to Hemodialysis Patients
This study used as the comparative drug (epoetin beta) will assess the efficacy and safety of intravenous injections of R744 in renal anemia patients on Hemodialysis patients.
- Trial name
- NCT00491868
- Testing
- R744, rHuEPO
- Where
- 5 sites in Japan
- Volunteers
- 134 people
- Sponsor
- Chugai Pharmaceutical
Muscle Cramp, Renal Dialysis
Stretching Exercises for Dialysis Patients to Reduce Muscle Cramps
This single-center, parallel-group randomized controlled trial aims to evaluate the effect of a nurse-led intradialytic stretching program on the burden of muscle cramps in patients receiving maintenance hemodialysis (HD).
- Conditions
- Muscle Cramp, Renal Dialysis, Exercise Therapy, Nursing Care
- Trial name
- NCT07262879
- Testing
- Nurse-Led Intradialytic Stretching Exercises
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University