Clinical trials: Maintenance Hemodialysis
Hepatitis B, ESRD (End Stage Renal Disease)
Comparing Hepatitis B Vaccination Schedules in Patients on Hemodialysis
People with kidney failure who are on dialysis have a weaker immune response to the hepatitis B vaccine than healthy people. Even after vaccination, many dialysis patients do not develop enough protection against hepatitis B…
- Conditions
- Hepatitis B, ESRD (End Stage Renal Disease), Kidney Failure, Chronic
- Trial name
- 3v4-HEP-DOSE (NCT07784452)
- Testing
- Recombinant Hepatitis B Vaccine - 3-Dose Schedule, Recombinant Hepatitis B Vaccine - 4-Dose Schedule
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Jinnah Hospital
To Evaluate the Clearance Rate of Uremic Toxin by HFR
Hemodiafiltration With Endogenous Reinfusion on Uremic Toxins Clearance of Maintenance Hemodialysis Patients
1.1Primary Objective To evaluate the clearance rate of uremic toxin β2-microglobulin (β2-MG), indoxyl sulfate and λ-free light chain (λFLC) by HFR.
- Trial name
- NCT06002529
- Testing
- HFR
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
End Stage Renal Disease (ESRD), Maintenance Hemodialysis
Impact of APP-assisted Patient Management on the Quality Control of Blood Purification Therapy
Many maintenance hemodialysis (MHD) patients develop negative outlooks due to their illnesses and complications, making their quality of life and prognosis a clinical concern.
- Trial name
- NCT07291154
- Testing
- APP-based management
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Yunfeng Xia
Restless Legs Syndrome, End Stage Renal Disease
Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD
Restless legs syndrome (RLS) is a neurologic disorder characterized by 1) an urge to move the legs, 2) uncomfortable sensations in the legs, 3) symptoms that are often worse the evening or when at rest , and 4) may be temporarily…
- Trial name
- NCT03708237
- Testing
- Ropinirole, Gabapentin
- Where
- 4 sites in Canada
- Volunteers
- 3 people
- Sponsor
- University of Alberta
Chronic Kidney Disease
Study of the Compliance With Phosphorus Restricted Diet and Phosphate Binder Therapy in Hemodialysis Patients
Hyperphosphatemia is a common and severe complication in chronic kidney disease patients treated with hemodialysis. A phosphate restricted diet and oral phosphate binders are the cornerstones in the prevention and treatment of…
- Trial name
- NCT01509027
- Testing
- education by DVD, Standard care, Education by DVD and dietician
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diuretic Abuse
Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management
Background.The objective of the present study is to verify whether using diuretics will improve either blood pressure or fluid overload in maintenance hemodialysis patients with residual diuresis kidney function.
- Trial name
- NCT04182854
- Testing
- Furosemid hydrochlorothiazide
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Capital Medical University
Hemodialysis Complication, Shoulder Joint Disorder
The Effect of Baduanjin on Shoulder Function in Maintenance Hemodialysis Patients
The aim of this study is to examine the effect of 18-month Baduanjin exercise on shoulder joint function in maintenance hemodialysis (MHD) patients.
- Conditions
- Hemodialysis Complication, Shoulder Joint Disorder, CKD-MBD
- Trial name
- NCT06314321
- Testing
- Baduanjin exercise
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Nantong University
Chronic Kidney Disease, Renal Osteodystrophy
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients
Sclerostin, the product of the SOST gene, located on chromosome 17, locus q11.2 in humans, was originally believed to be a non-classical Bone morphogenetic protein (BMP) antagonist.Sclerostin was recently identified as a…
- Conditions
- Chronic Kidney Disease, Renal Osteodystrophy, Left Ventricular Hypertrophy
- Trial name
- NCT01382966
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- RFM Renal Treatment Services
Protein-Energy Malnutrition, Hemodialysis
Impact of Cannabis Oil on Nutrition in Hemodialysis Patients Study (ICON-HP Study)
The study will be performed in two parts: 1) The pharmacokinetic (PK) part and 2) The appetite and nutritional evaluation part. The PK part of study will be conducted in open label manner on 10 end stage kidney disease (ESKD)…
- Conditions
- Protein-Energy Malnutrition, Hemodialysis, Appetite Disorders
- Trial name
- ICON-HP (NCT03664141)
- Testing
- Cannabis oil
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Hepatitis C, Hemodialysis
Effect of HCV Infection on Insulin Resistance and Malnutrition-inflammation Complex Syndrome in Regular Hemodialysis Patients
The purpose of this study is to study whether hepatitis C virus (HCV)infected maintenance hemodialysis (MHD)patients have distinct metabolic, inflammatory and adipokine characteristics that can be linked to poor clinical outcome…
- Conditions
- Hepatitis C, Hemodialysis, Quality of Life, Mortality
- Trial name
- NCT00527774
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- St. Martin De Porress Hospital
End-Stage Renal Disease, Gut Microbiome Dysbiosis
Gut Microbiome and p-Inulin in Hemodialysis
The Microbiome trial is a non-randomized, open-label, sequential, multi-center study of p-inulin for patients with hemodialysis-dependent end-stage renal disease.
- Trial name
- NCT02572882
- Testing
- p-inulin
- Where
- 4 sites in United States
- Volunteers
- 13 people
- Sponsor
- University of Pennsylvania
Anemia of Chronic Kidney Disease
A Study to Evaluate Efficacy and Safety of JTZ-951 Compared to Darbepoetin Alfa in Korean Renal Anemia Patients Receiving Hemodialysis.
JTZ-951 is a currently being developed as a treatment for renal anemia. This study aims to evaluate the efficacy and safety of JTZ-951 following a switch from erythropoiesis-stimulating agent (ESA) in Korean subjects receiving…
- Trial name
- NCT04027517
- Testing
- JTZ-951, Darbepoetin Alfa
- Where
- South Korea
- Volunteers
- 172 people
- Sponsor
- JW Pharmaceutical
Nurse-Patient Relations
The Effect of Foot Massage in Patients Undergoing Hemodialysis
Hemodialysis patients were divided into experimental and control groups. Foot massage was applied to the patients in the experimental group.
- Trial name
- NCT06217497
- Testing
- Foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Harran University
Chronic Kidney Disease, End Stage Renal Disease
Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease
The purpose of this open-label extension study is to evaluate long-term efficacy and safety of roxadustat in maintaining hemoglobin (Hb) in participants with dialysis and non-dialysis chronic kidney disease (CKD) who have…
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Anemia
- Trial name
- NCT01630889
- Testing
- Roxadustat
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 15 people
- Sponsor
- Kyntra Bio
Cardio-cerebral Vascular Events, Arteriovenous Fistula Dysfunction
Impact and Mechanism of Depression on Cardio-cerebral Vascular Events and Arteriovenous Fistula Dysfunction in MHD Patients
Depression is a common psychiatric disorder in patients on maintenance hemodialysis (MHD). It may contribute to poor prognosis in a number of ways, including its effect on platelet function.
- Trial name
- NCT06070805
- Testing
- depression
- Where
- China
- Volunteers
- 286 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
End Stage Renal Disease on Dialysis
Study on the Influence of Dyadic Psychoeducational Intervention on Patients With Maintenance Hemodialysis
This study aims explored the effectiveness of dual psychological intervention strategies in improving the quality of life of MHD patients based on the theoretical guidance of double ABC-X model.
- Trial name
- MHD (NCT06203730)
- Testing
- dyadic psychological intervention strategy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jiangsu Taizhou People's Hospital
End Stage Renal Disease, Kidney Disease
Effects of PINTA 745 in End Stage Renal Disease (ESRD) Patients Who Require Hemodialysis and Have Protein Energy Wasting
This is a pilot study to assess the safety, pharmacokinetics and effectiveness of PINTA 745 or placebo in treating protein energy wasting (PEW) in patients receiving maintenance hemodialysis (MHD).
- Conditions
- End Stage Renal Disease, Kidney Disease, Protein Energy Wasting
- Trial name
- NCT01958970
- Testing
- PINTA 745
- Where
- 6 sites in United States
- Volunteers
- 51 people
- Sponsor
- Pinta Biotherapeutics
Anemia of Chronic Kidney Disease
Comparison Study of Two Iron Compounds for Treatment of Anemia in Hemodialysis Patients
Patients with end-stage kidney disease on maintenance hemodialysis frequently require iron supplementation to compensate for ongoing iron losses, and to maintain hemoglobin levels with or without additional use of…
- Trial name
- COPEFER (NCT02198495)
- Testing
- Supplementation of ferric carboxymaltose, Supplementation of iron sucrose
- Where
- 2 sites in Austria
- Volunteers
- 143 people
- Sponsor
- Medical University of Vienna
Hemoperfusion
HP Improves Sleep and Overall Survival Rate in Maintenance Hemodialysis Patients
Sleep disturbance has been long-standing torments in most of patients with maintenance hemodialysis (HD). In this study, we attempted to explore whether long-term hemoperfusion (HP) could improve sleep disorder and increase…
- Trial name
- NCT03487146
- Testing
- hemoperfusion(HP)
- Volunteers
- 156 people
- Sponsor
- Shanghai Pudong Hospital
Secondary Hyperparathyroidism, Maintenance Hemodialysis
The Efficacy and Safety of Microwave Ablation for Mild-to-moderate Secondary Hyperparathyroidism Patients Undergoing Hemodialysis
Microwave ablation, as a new method to therapy secondary hyperparathyroidism(SHPT), now is developing rapidly. However, it is still unknown whether it is effective to accept microwave ablation for hemodialysis patients with…
- Trial name
- NCT02332135
- Testing
- microwave ablation, active vitamin D
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Wenhu Liu