Clinical trials: Maintenance Therapy
Sleep, Sleep Quality
A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children
The main goal of this study is to evaluate the "SIESTA" intervention, a culturally and contextually tailored sleep hygiene intervention that has the potential to exert greater improvements in sleep hygiene and sleep outcomes for…
- Conditions
- Sleep, Sleep Quality, Intervention Study, Ethnic Minority
- Trial name
- SIESTA (NCT06942455)
- Testing
- SIESTA, Sleep education and health education control
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Atrial Fibrillation
Risk Factors That Contribute to the Maintenance of Sinus Rhythm
This is a prospective clinical research study. The objective of this study is to evaluate if clinical risk factors as well as structural features on echocardiography affect the maintenance of sinus rhythm after electrical…
- Trial name
- Afib (NCT04655443)
- Testing
- Standard Care
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Danbury Hospital
Obesity
Adipogenic Capacity as a Mediator of Weight Gain
To demonstrate differences in response of subjects with a high, low or medium predisposition for weight regain after weight reduction in terms of: body composition; energy expenditure; physical activity; and adipogenic capacity.
- Trial name
- NCT01015508
- Testing
- Very Low Energy Diet (VLED), Weight maintenance
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Leukemia
Chlorambucil in Treating Patients With Advanced Chronic Lymphocytic Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which chlorambucil regimen is more effective in treating advanced chronic lymphocytic…
- Trial name
- NCT00017108
- Testing
- chlorambucil, cyclophosphamide, fludarabine phosphate
- Where
- 13 sites in Belgium, Czechia and 5 more
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Insomnia, Suicidal Ideation
RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts
There is a strong association between insomnia and suicidal thoughts and behaviors. Insomnia also frequently co-occurs with other common conditions associated with suicide such as depression and posttraumatic stress disorder.
- Trial name
- NCT03603717
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
- Where
- 3 sites in United States
- Volunteers
- 283 people
- Sponsor
- VA Office of Research and Development
Cerebral Palsy, Sleep Disorders
Sleep Quality, Caregiver Burden, Stress, and Self-Efficacy in Parents of Children With Spastic Diplegic Cerebral Palsy: A Comparison by Night Orthosis Use
This observational study aims to compare sleep quality, caregiver burden, stress, and self-efficacy between parents of children with spastic diplegic cerebral palsy who use night orthoses and those who do not.
- Conditions
- Cerebral Palsy, Sleep Disorders, Caregiver Burden
- Trial name
- NCT07846917
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Post Traumatic Stress Disorder, Insomnia
Evaluation of Yoga for Sleep Disturbances in Post Traumatic Stress Disorder (PTSD)
The primary objective of this preliminary study is to estimate sleep outcome effect sizes and determine feasibility for a novel yoga treatment of insomnia in participants with post traumatic stress disorder (PTSD).
- Trial name
- NCT01556074
- Testing
- Yoga treatment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Insomnia
Long-term Follow-up of Functional Performance and Exercise Efficacy in Community-dwelling Elderly With Insomnia
Poor sleep quality has been recognized as a major public health concern in the world. The prevalence of insomnia in Taiwan is comparable to that of Western countries.
- Trial name
- NCT01689818
- Testing
- exercise training
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COPD
Has Pulmonary Rehabilitation a Positive Impact on Sleep Quality in Patients Suffering From COPD ?
The purpose of our study is to assess the impact of pulmonary rehabilitation on objective sleep quality in COPD patients.
- Trial name
- NCT03314558
- Testing
- pulmonary rehabilitation
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Diffuse Large B Cell Lymphoma
Zanubrutinib-based Maintenance Therapy of Newly Diagnosed DLBCL With Initial Remission
This single-arm, prospective clinical study will evaluate the efficacy and safety of Zanubrutinib-based maintenance therapy for post-remission in newly diagnosed DLBCL who are intolerant to first-line intensive chemotherapy.
- Trial name
- NCT06669143
- Testing
- Zanubrutinib, Lenalidomide
- Volunteers
- 19 people
- Sponsor
- Ruijin Hospital
Nursing, Hemodialysis Patient
THE EFFECTS OF CIRCADIAN RHYTHM-BASED PROGRESSIVE RELAXATION EXERCISES IN HEMODIALYSIS PATIENTS
The aim of this study is to determine the effect of Progressive Relaxation Exercise (PGE) applied according to the circadian rhythms of hemodialysis (HD) patients on symptom management, sleep quality, comfort and mental…
- Conditions
- Nursing, Hemodialysis Patient, Circadian Rhythm, Relaxation Exercise
- Trial name
- NCT07499297
- Testing
- Progressive Relaxation Exercises
- Volunteers
- 75 people
- Sponsor
- Karamanoğlu Mehmetbey University
Insomnia Disorder
A Study to Evaluate the Efficacy and Safety of Daridorexant in Participants With Insomnia Disorder
The purpose of this phase 3 study is to evaluate the efficacy and safety of Daridorexant compared to in participants with insomnia disorder.
- Trial name
- NCT07028697
- Testing
- Daridorexant
- Where
- 17 sites in South Korea
- Volunteers
- 164 people
- Sponsor
- Nxera Pharma Korea Co., Ltd.
Extensive-stage Small Cell Lung Cancer
Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer
The purpose of the study is to determine whether adding vorolanib to atezolizumab will improve the length of time that participants are cancer-free after receiving standard chemotherapy.
- Trial name
- NCT04373369
- Testing
- Vorolanib, Atezolizumab
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Washington University School of Medicine
Asthma
Study to Investigate Real Life Effectiveness of Symbicort Maintenance and Reliever Therapy in Asthma Patients Across Asia
The purpose of this study is to compare whether Symbicort Maintenance \& Reliever Therapy (SMART) is more effective in uncontrolled asthmatic patients than their current therapy in a real life situation.
- Trial name
- SMARTASIA (NCT00939341)
- Testing
- Symbicort (Budesonide/Formoterol)
- Where
- 35 sites in China, India and 3 more
- Volunteers
- 862 people
- Sponsor
- AstraZeneca
Chronic Hepatitis B in HIV Patient, Kidney Injury
Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide as Maintenance Treatment for HIV/HBV-coinfection
Tenofovir alafenamide (TAF), active against both HIV and HBV, demonstrates similar antiviral efficacy but improved renal and bone safety compared to tenofovir disoproxil fumarate (TDF) in HIV-1-infected patients.
- Conditions
- Chronic Hepatitis B in HIV Patient, Kidney Injury, Bone Diseases
- Trial name
- NCT03425994
- Testing
- Elvitegravir/Cobicistat/Emtricitabine
- Where
- Taiwan
- Volunteers
- 275 people
- Sponsor
- National Taiwan University Hospital
HIV, AIDS
Maintenance Boosted Lopinavir Monotherapy Following Salvage Protease-inhibitor (PI) Based Regimen in HIV With Non-nucleoside Reverse Transcriptase Inhibitors (NNRTI) Based Regimen Failure
The objective of this study is to determine efficacy of ritonavir-boosted lopinavir monotherapy as a maintenance regimen in HIV-1-infected patients who previously failed Non-nucleoside reverse transcriptase inhibitors (NNRTI)…
- Conditions
- HIV, AIDS, Lopinavir, Treatment Failure
- Trial name
- BIDI-MONO (NCT01189695)
- Testing
- Ritonavir-boosted lopinavir, optimized background regimens (OBRs)
- Where
- Thailand
- Volunteers
- 63 people
- Sponsor
- Bamrasnaradura Infectious Diseases Institute
Acute Promyelocytic Leukemia
Single Agent Arsenic Trioxide in the Treatment of Newly Diagnosed Acute Promyelocytic Leukemia
There is very limited data on the use of arsenic trioxide in newly diagnosed patients with acute promyelocytic leukemia. The use of arsenic trioxide was limited to relapsed patients mainly because of the superior efficacy of ATRA…
- Trial name
- IAPLSG04 (NCT00517712)
- Testing
- Single agent arsenic trioxide
- Where
- 9 sites in India
- Volunteers
- 400 people
- Sponsor
- Christian Medical College, Vellore, India
Gynecologic Neoplasms
Impact of Preoperative Sleep Quality and Anxiety on Postoperative Outcomes in Abdominal Gynecologic Cancer Surgery
This prospective observational study aims to evaluate the effects of preoperative sleep quality and anxiety levels on postoperative outcomes in patients undergoing abdominal gynecologic cancer surgery.
- Trial name
- NCT07036549
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Izmir City Hospital
Lymphocytic Leukemia, Chronic
A Study to Assess the Effect of Maintenance Treatment With Rituximab Versus No Treatment in Participants With Progressive B-Cell Chronic Lymphocytic Leukemia (CLL)
This study will assess the effect of maintenance treatment with rituximab in comparison with observation period (no treatment), in participants with progressive B-cell CLL who have had previous first-line induction treatment with…
- Trial name
- NCT00718549
- Testing
- Cladribine, Cyclophosphamide, Rituximab
- Where
- 6 sites in Belarus, Poland
- Volunteers
- 128 people
- Sponsor
- Hoffmann-La Roche