Clinical trials: Major Abdominal Surgery
Postoperative Pulmonary Complications (PPCs), Abdominal Surgeries
Can Ultrasound-Guided Fascial Plane Blocks Reduce Postoperative Pulmonary Complications After Major Abdominal Surgery?
This prospective observational study aims to evaluate whether the use of ultrasound-guided fascial plane blocks is associated with a lower incidence of postoperative pulmonary complications in adult patients undergoing elective…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Abdominal Surgeries, Postoperative Pain Management
- Trial name
- FPB-PPC (NCT07394816)
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Dyspnea, Pain
Effectiveness of I COUGH Program to Dyspnea, Respiratory Parameters, Mobility and Pain After Major Abdominal Surgery
The purpose of the current study was to investigate the effect of the I COUGH care program following major abdominal surgery dyspnea, oxygen saturation, pulmonary function, mobility, and pain after major abdominal surgery (MAS)…
- Conditions
- Dyspnea, Pain, Respiratory Insufficiency, Mobility Limitation
- Trial name
- NCT06255327
- Testing
- I COUGH care program
- Where
- 3 sites in Libya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Intraoperative Myocardial Depression
Dobutamine During Major Abdominal Surgery
The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.
- Trial name
- PUSH-1 (NCT07000994)
- Testing
- Dobutamine, Routine care
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Hamburg-Eppendorf
Postoperative Inflammation
A Comparative Study of Volume Replacement With HES 130/0.4 Versus Ringer's Lactate (RL) Regarding Their Effects on Inflammatory Biomarkers (Cytokines and Matrix Metalloproteinases) Responses to Major Abdominal Surgery.
Various stimuli such as trauma, infection and major surgery may alter the physiologic immune balance and initiate systemic inflammatory processes.
- Trial name
- NCT01880190
- Testing
- Ringer's Lactate, HES 130/0.4 and Ringer's Lactate
- Where
- Greece
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Adverse Anesthesia Outcome
Liberal Versus Goal-directed Intraoperative Fluid Therapy in Pediatric Patients
The objectives of this study are 1) to investigate the influence of different fluid regimen (Liberal regimen versus Goal directed therapy regimen) on postoperative outcome such as weight gain, delayed gut function recovery…
- Trial name
- GDT (NCT01350076)
- Testing
- conventional liberal fluid regimen, restricted fluid regimen
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Pain, Postoperative, Opioid Use
Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial
Major abdominal surgery continues is one of the most performed surgical procedures in the world, both electively and urgently. One of the main problems of this type of intervention is postoperative pain.
- Trial name
- NCT04017013
- Testing
- Epidural Analgesia, Lidocaine Infusion
- Where
- Colombia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Abdominal Surgery, Postoperative Recovery
Effect of AI-Personalized Virtual Reality on Postoperative Recovery After Major Abdominal Surgery
Major abdominal surgery is frequently associated with postoperative pain, anxiety, delayed recovery, and prolonged hospitalization.
- Conditions
- Abdominal Surgery, Postoperative Recovery, Postoperative Pain, Length of Hospital Stay
- Trial name
- VR-RECOVER (NCT07493499)
- Testing
- Immersive Virtual Reality (VR), Standard Perioperative Care and Enhanced Recovery Protocol
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Alexandria University
Postoperative Care
Postoperative Oral Intake Trial
Complete fasting until resumed bowel function after upper abdominal surgery is not beneficial. Enteral feeding has been claimed to be the preferred way of delivering nutritional support postoperatively.
- Trial name
- NCT00134407
- Testing
- Normal diet, Nutrition via jejunal needle-catheter
- Where
- Norway
- Volunteers
- 450 people
- Sponsor
- University Hospital of North Norway
Abdominal Aortic Aneurysm Uncomplicated
Goal Directed Therapy for Patients Undergoing Major Vascular Surgery
The management and delivery of intravenous fluids during surgical operations is one of the important duties for anesthesiologists.
- Trial name
- NCT01681251
- Testing
- Fluid titrated with the use of arterial pulse contour cardiac output monitor if SVV >13%, Fluid titrated at the discretion of the attending anesthesiologist
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Abdominal Wall Hernia, Pancreatic Diseases
IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Number of patients with unsatisfactory pain relief defined as average visual analog scale (VAS) more than 5 with or without requirement of IVPCA for pain relief during the first 48 hours postoperative period will be compared…
- Conditions
- Abdominal Wall Hernia, Pancreatic Diseases, Bowel Disease, Gastric Disease
- Trial name
- NCT03198871
- Testing
- Acetaminophen Injectable Product, Sodium Chloride 0.9%, Intravenous
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kathirvel Subramaniam
Major Thoracic and Abdominal Surgery
Automatic Oxygen Administration After Major Abdominal and Thoracic Surgery
The aim of the study is to assess the use feasibility of the FreeO2 system so as to deliver automatically oxygen in the post anesthesia care unit in a patient population admitted for major abdominal and thoracic surgery.
- Trial name
- FreeO2PostOp (NCT02546830)
- Testing
- FreeO2 v2.2 active, FreeO2 v2.2 with manual oxygenation
- Where
- 5 sites in Canada, France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Recovery From Anesthesia
The Effect of Preoperative Aminophylline
Several clinical studies and case reports suggested that aminophylline antagonizes the effects of diazepam , barbiturates , sevoflurane ,morphineand propofol.However, the available results from uncontrolled clinical settings make…
- Trial name
- NCT04151381
- Testing
- Aminophylline
- Where
- 2 sites in Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Postoperative Acute Kidney Injury, Postoperative Complications
Hypotension Prediction Index-guided Hemodynamic Optimization Trial to Reduce Postoperative Acute Kidney Injury (HYT).
MAIN AIM OF THE STUDY To establish whether hemodynamic management guided by the hypotension prediction index (HPI) guided by the administration of intravenous fluids and vasoactive drugs in patients undergoing elective major…
- Trial name
- HYT (NCT05569265)
- Testing
- Intraoperative hemodynamic management
- Where
- 26 sites in Spain
- Volunteers
- 958 people
- Sponsor
- Maria José Clara Colomina Soler
Pulmonary Complication
Respiratory Exercise Diary in Major Abdominal Surgery
Postoperative pulmonary complications are common and lead to increased morbidity and mortality in patients. These complications are observed especially after major surgical interventions.
- Trial name
- NCT06078644
- Testing
- respiratory exercise diary
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Surgery, Temperature Change, Body
Intraoperative Body Core Temperature Monitoring: Oesophageal Probe vs Heated Controlled Servo Sensor
Monitoring of intraoperative core temperature is essential for patient safety, reducing the risk of perioperative hypothermia. A recently developed measuring system, SpotOn® (3M, St.
- Trial name
- ESOSPOT (NCT03820232)
- Testing
- temperature monitoring
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Careggi Hospital
Bladder Cancer
FITBIT Study on Mobility and Readmissions After Radical Cystectomy
This is a two-arm randomized, controlled trial during the postoperative period after major abdominal surgery for cancer, including for example radical cystectomy, nephrectomy, colectomy, comparing a control group that uses a…
- Trial name
- FITBIT (NCT04314778)
- Testing
- social incentive-based gamification
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of Pennsylvania
Surgery, Postoperative Complications
Impact of Caloric and Protein Adequacy on Postoperative Clinical Outcomes of Patients Undergoing Major Abdominal Surgery
The role of nutritional therapy (TN) in the surgical patient is well described in the literature and is associated with reductions in postoperative complications, length of hospital stay, and mortality.
- Conditions
- Surgery, Postoperative Complications, Cancer, Energy Supply; Deficiency
- Trial name
- NCT03357848
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Minas Gerais
Major Elective Abdominal and Thoracic Surgery
Evaluation of Glycocalyx in Major Abdominal and Thoracic Surgery
Background: The glycocalyx is a fundamental component of the endothelial barrier and alterations at this level have been shown to exacerbate the inflammatory response in the microcirculation.
- Trial name
- NCT04900779
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Technology
Evaluation of the IKORUS Technology in Patients Undergoing Major Abdominal Surgery
The goal of this observational substudy is to evaluate the feasibility, performance and behavior of the IKORUS (Advanced Perfusion Diagnostics, Villeurbanne, France), a new tissue perfusion device using urethral…
- Trial name
- NCT04187274
- Testing
- IKORUS technology
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Erasme University Hospital