Clinical trials: Major Wound Complications
Acute Kidney Injury, Chronic Kidney Disease
Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis
Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease, Hypertension
- Trial name
- IMPRESS (NCT02372721)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Alzheimer Disease, Late Onset, Stroke
Explore the Sharing Model Intervene to Improve the Knowledge, Attitudes, Service Intentions and Service Start-up Effects of the Eight Major Non-cancer Disease End-stage Caregivers on Well-being and Palliative Care
Since September 1st, 2009, Taiwan has begun to pay attention to the care of patients with organ failure, dementia and the elderly, and brought eight of non-cancer terminal patients into health insurance subsidies to implement the…
- Conditions
- Alzheimer Disease, Late Onset, Stroke, Heart Failure, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT05407272
- Testing
- Health Education Manual, manual
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wen-Shiou Pan
Sepsis, Severe, Acute Kidney Injury
MR-Evaluation of Renal Function In Septic Patients
A study of renal blood flow and renal oxygenation measured by magnetic resonance after a standardized fluid challenge in critically ill, resuscitated, patients with sepsis due to COVID-19 or other agents.
- Conditions
- Sepsis, Severe, Acute Kidney Injury, COVID-19
- Trial name
- MERSEP (NCT02765191)
- Testing
- Plasma expansion with Ringer's Acetate
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Uppsala University
Sequelae of; Infection, Post Infection Glomerulonephritis
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period.
- Conditions
- Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder)
- Trial name
- sequelae (NCT04846010)
- Testing
- PurWet, FurFat, PurApo
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- All Natural Medicine Clinic, LLC
Complication of Labor and Delivery
Palestinian Perineum and Birth Complication Study
In this study the investigators want to assess complications associated to pregnancy and delivery, and interventions used during labor. Pregnancy and delivery related complications are a major health problem globally.
- Trial name
- PPS (NCT02427854)
- Testing
- Education by animated training video, Interactive hands-on bedside training
- Where
- 4 sites in Palestinian Territories
- Volunteers
- 51,041 people
- Sponsor
- Oslo University Hospital
Metabolic Acidosis, Acute Kidney Injury
Sodium Bicarbonate for the Treatment of Severe Metabolic Acidosis With Moderate or Severe Acute Kidney Injury in ICU
Severe metabolic acidemia in the critically ill (pH equal or less than 7.20; PaCO2 equal or less than 45mmHg and bicarbonate concentration equal or less than of 20 mmol/l) is associated with a 50% rate of day 28 mortality.
- Trial name
- BICARICU-2 (NCT04010630)
- Testing
- Sodium bicarbonate infusion
- Where
- France
- Volunteers
- 640 people
- Sponsor
- University Hospital, Montpellier
Pain, Postoperative, Wound; Abdomen
Surgical Versus Anaesthetic Placement of Rectus Sheath Catheters
This is a single centred randomized controlled trial comparing surgeon versus anaesthetist inserted rectus sheath catheters for management of analgesia post major abdominal surgery.
- Conditions
- Pain, Postoperative, Wound; Abdomen, Incision
- Trial name
- SPARC (NCT03137732)
- Testing
- Rectus Sheath Catheter
- Volunteers
- 50 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Refractory Multiple Myeloma
Tivantinib in Treating Patients With Relapsed, or Relapsed and Refractory Multiple Myeloma
This phase II trial studies the side effects and how well tivantinib works in treating patients with relapsed, or relapsed and refractory multiple myeloma.
- Trial name
- NCT01447914
- Testing
- Tivantinib, Diagnostic laboratory biomarker analysis, Questionnaire administration
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Cancer Institute (NCI)
Surgical Site Infection, Surgical Procedures, Operative
Polihexanide SSIs Measures Bundle (PSMB) During Enhanced Recovery After Major Digestive Surgery
This is a randomized controlled, prospective, multicenter superiority trial with two parallel treatment groups and single blinding (local investigators performing postoperative follow up will be blinded for group allocation)…
- Trial name
- POSSIBLE (NCT06338163)
- Testing
- Polihexanide-based bundle, Standard bundle
- Where
- 3 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- Marco Catarci
Acute Kidney Injury
Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery
This project aims to conduct an international, prospective, multicentre, observational study to determine the incidence of Postoperative Acute Kidney Injury (PO-AKI) in hospitalized children after noncardiac surgery.
- Trial name
- POAKIDS (NCT07351149)
- Where
- 16 sites in Australia, Brazil and 8 more
- Volunteers
- 2,000 people
- Sponsor
- Uppsala University
Tracheostomy Complication, Acquired Brain Injury
Cough Assessment in Patients With Severe Acquired Brain Injury
The cough assessment is fundamental in the weaning process as it gives information on the possibility to expel food and secretion out from the airways.
- Conditions
- Tracheostomy Complication, Acquired Brain Injury, Brain Injury, Pneumonia
- Trial name
- NCT02495558
- Testing
- Reflex Cough Test
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Acute Kidney Injury
Acute Kidney Injury in Severe Trauma
Acute kidney injury (AKI) represents a serious complication following severe injury associated with adverse outcome. Main goals of the presented study were to define the incidence of AKI and to evaluate the validity of AKI…
- Trial name
- NCT03433079
- Testing
- Neutrophil gelatinase-associated lipocalin (NGAL), Arterial lactate, Interleukin-6 (IL-6)
- Where
- Czechia
- Volunteers
- 81 people
- Sponsor
- University Hospital Ostrava
Acute Renal Failure
Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF).
This study seeks to determine if increasing the dose of continuous renal replacement therapy (CRRT) reduces 90-day all cause mortality in Intensive Care Unit (ICU) patients with severe acute renal failure (ARF).
- Trial name
- NCT00221013
- Testing
- "augmented" CRRT regimen
- Where
- Australia
- Volunteers
- 1,508 people
- Sponsor
- The George Institute
Acute Ischemic Stroke, Acute Renal Injury
Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation
The aim of this trial is to assess the safety and efficacy of conestat alfa (Ruconest®, Pharming Technologies B.V.) on renal and cerebral ischemic events in patients undergoing TAVI for severe symptomatic aortic stenosis (AS)…
- Trial name
- PAIR-TAVI (NCT05145283)
- Testing
- Conestat alfa (Ruconest®), NaCl 0.9%)
- Where
- 2 sites in Switzerland
- Volunteers
- 141 people
- Sponsor
- University Hospital, Basel, Switzerland