Clinical trials: Male Erectile Disorder
Anterior Ischemic Optic Neuropathy
PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
The primary objective of this study is to determine whether the use of PDE5 inhibitors (vardenafil, sildenafil, or tadalafil) increases the risk for the development of NAION.
- Trial name
- NCT00867815
- Testing
- Diagnostic procedures
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 10 people
- Sponsor
- Bayer
Prostate Cancer, Sexual Dysfunction
Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy
RATIONALE: Tadalafil may help prevent erectile dysfunction (ED) in patients with prostate cancer that has been treated with radiation therapy.
- Trial name
- NCT00931528
- Testing
- Tadalafil
- Where
- 192 sites in United States, Canada
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Radiation Therapy Oncology Group
Erectile Dysfunction, Cardiovascular Diseases
Identification of Underlying Conditions in Men Prescribed a PDE5 Inhibitor
Erectile dysfunction (ED) has been identified as an independent risk factor for existing cardiovascular disease, preceding a major cardiovascular event by an average of about 5 years.
- Conditions
- Erectile Dysfunction, Cardiovascular Diseases, Male Urogenital Diseases
- Trial name
- NCT01150903
- Testing
- no intervention
- Volunteers
- 98,832 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Titan® One Touch Release Inflatable Penile Prosthesis
The purpose of this study is to assess the ease of deflation of the Titan® OTR pump.
- Trial name
- NCT00731939
- Testing
- Inflatable Penile Prosthesis
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 124 people
- Sponsor
- Coloplast A/S
Sexual Dysfunction, Erectile Dysfunction
Botulinum Toxin for Erectile Dysfunction
To evaluate the safety and efficacy of intra-cavernosal Botulinum toxin injection as an alternative line of treatment in patients with erectile dysfunction - not responding to oral PDE5i - through cavernosal smooth muscle…
- Trial name
- NCT03102762
- Testing
- Botulinum Toxin Type A, Normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Prostate Cancer, Erectile Dysfunction
Study of Sildenafil Citrate During and After Radiotherapy/Hormone Therapy for Erectile Function Versus Radiotherapy/Hormone Therapy for Prostate Cancer
Radiation sometimes affects the ability for a person to have a normal erection. Complete loss of erections after radiation treatment can happen in 40-50% of treated patients.
- Trial name
- NCT00142506
- Testing
- sildenafil citrate and questionaires
- Where
- 5 sites in United States
- Volunteers
- 290 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Erectile Dysfunction
A Study of Tadalafil and Sildenafil in Men With Erectile Dysfunction in China
The primary objective of this study is to evaluate whether, after two 8-week treatment periods, male patients with erectile dysfunction (ED) in China prefer 20 milligram (mg) tadalafil or 100 mg sildenafil.
- Trial name
- NCT01352507
- Testing
- Tadalafil, Sildenafil
- Where
- 9 sites in China
- Volunteers
- 383 people
- Sponsor
- Eli Lilly and Company
Impotence
Impact Of Viagra On Sexual Satisfaction Of Men With Mild Erectile Dysfunction Who Are Sexually Dissatisfied
Men's quality of life (QoL) is potentially affected by mild erectile dysfunction (ED) to the same extent as it is by moderate and severe ED.
- Trial name
- NCT00301262
- Testing
- Viagra (Sildenafil citrate)
- Where
- 26 sites in Canada
- Volunteers
- 183 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Safety and Efficacy of Autologous Platelet-Rich Plasma for Erectile Dysfunction.
The purpose of this study is to evaluate changes in vascular parameters and International Index of Erectile Function (IIEF) scores with the administration of Platelet Rich Plasma (PRP) to participants with Erectile Dysfunction…
- Trial name
- NCT04396795
- Testing
- Autologous Platelet Rich Plasma, Saline solution
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Miami
Erectile Dysfunction, Benign Prostatic Hyperplasia
A Study in the Treatment of Erectile Dysfunction and Benign Prostate Hyperplasia
Study LVHR is a Phase 3 study which will examine the efficacy and safety of tadalafil 2.5 and 5 mg once daily versus placebo for the treatment of erectile dysfunction (ED) and signs and symptoms of benign prostatic hyperplasia…
- Trial name
- COMORBID© (NCT00855582)
- Testing
- Tadalafil
- Where
- 52 sites in United States, Canada and 7 more
- Volunteers
- 606 people
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction
Randomized Trial of Ropivacaine & Bupivacaine for Inflatable Penile Prosthesis
The purpose of this research is to determine the effects of penile ring block for local anesthesia with liposomal bupivacaine vs ropivacaine mixture in subjects undergoing surgery for Penile Prosthesis Placement.
- Trial name
- ROVEX-IPP (NCT04801368)
- Testing
- Randomization of two local anesthetics.
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Erectile Dysfunction, Prostate Cancer
A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy
The purpose of the study is to compare the safety and effectiveness of Prograf in the prevention of erectile dysfunction in men after a radical prostatectomy.
- Trial name
- NCT00106392
- Testing
- Tacrolimus
- Where
- 6 sites in United States
- Volunteers
- 131 people
- Sponsor
- Astellas Pharma Inc
Impotence
Tadalafil Taken Daily Compared to Placebo on Improvement of Getting and Maintaining an Erection and Sexual Quality of Life
To determine if tadalafil 5 mg daily compared to placebo when given for 12 weeks improves getting and maintaining an erection in men with erectile dysfunction and if there are improvements in the sexual quality of life of the man…
- Trial name
- NCT00422734
- Testing
- tadalafil
- Where
- 19 sites in United States, Austria and 3 more
- Volunteers
- 342 people
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction
Vardenafil ODT Versus Placebo in Males With Erectile Dysfunction
This study investigates the safety and efficacy of a new dosage form of Vardenafil, an orodispersible tablet (ODT), and compares it to the safety and efficacy of a placebo (inactive) tablet in the treatment of erectile…
- Trial name
- NCT00631969
- Testing
- Vardenafil ODT (STAXYN, BAY38-9456)
- Where
- 47 sites in Belgium, France and 4 more
- Volunteers
- 362 people
- Sponsor
- Bayer
Seizure Disorder, Hypogonadism
Treatment of Sexual Dysfunction in Hypogonadal Men With Epilepsy With Testosterone and Either Anastrozole or Placebo
The purpose of this study is to determine if treatment using a medication (anastrozole/Arimidex), which lowers estrogen levels in the blood is better than placebo, a tablet that does not contain any active medication, when…
- Conditions
- Seizure Disorder, Hypogonadism, Erectile Dysfunction
- Trial name
- NCT00179517
- Testing
- Anastrozole 1mg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Deaconess Medical Center
Erectile Dysfunction, Sexual Dysfunction
Concomitant Use of PriLigy in Men Treated for Erectile Dysfunction
The purpose of this study is to evaluate the efficacy and safety of dapoxetine compared to placebo in men with premature ejaculation and erectile dysfunction who are currently being treated with a phosphodiesterase-5 inhibitor…
- Trial name
- COUPLE (NCT01063855)
- Testing
- Dapoxetine, PDE5I (phosphodiesterase-5 inhibitor)
- Where
- 69 sites in United States, Argentina and 11 more
- Volunteers
- 495 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Erectile Dysfunction, Lower Urinary Tract Symptoms
An Efficacy Study to Evaluate Alfuzosin to Treat Men With Erectile Dysfunction and Mild Lower Urinary Tract Symptoms
The purpose of this study is to assess the effect of Alfuzosin in treating Erectile Dysfunction in men with mild lower urinary tract symptoms based upon a change from baseline in erectile function (EF) domain of International…
- Trial name
- NCT00893113
- Testing
- Alfuzosin
- Where
- 4 sites in United States
- Volunteers
- 74 people
- Sponsor
- Chesapeake Urology Research Associates