Clinical trials: Male Erectile Dysfunction
Erectile Dysfunction
A Study to Assess the Safety and Tolerability Profile of TR399 in Healthy Volunteers and Erectile Dysfunction Patients
The purpose of this phase I/IIa study is to assess the safety and tolerability profile of TR399 in healthy volunteers and erectile dysfunction patients. This study will be conducted via a single-arm and open-label fashion.
- Trial name
- NCT03102398
- Testing
- TR-399 (5% Vardenafil HCl·3H2O, topical gel)
- Where
- Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Tritech Biopharmaceuticals Co., Ltd.
Prostatic Hyperplasia, Benign, Erectile Dysfunction
Efficacy and Safety of the DTT106 in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia
The purpose of this study is to assess the safety and efficacy of the DTT106 in the treatment of erectile dysfunction associated with benign prostatic hyperplasia
- Trial name
- AUSTRÁLIA (NCT06264414)
- Testing
- DTT106, Dutasteride-Tamsulosin
- Where
- Brazil
- Volunteers
- 262 people
- Sponsor
- EMS
Erectile Dysfunction Following Urethral Surgery
Tadalafil Daily Used Post Turp
to assess the effect of early tadalafil 5 mg once daily on persistent storage lower urinary tract symptoms (LUTS) and erectile function after transurethral resection of the prostate (TURP).
- Trial name
- NCT06788704
- Testing
- Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Kafrelsheikh University
Erectile Dysfunction
Low Intensity ShockWave Therapy for ED in Non Responders to PDE5i - a Double Blind Placebo Controlled Study
Low intensity shock waves (LISW) have been proven in animal studies to induce local growth of new blood vessels. The investigators hypothesized that LISW therapy could improve the symptoms of patients with erectile dysfunction…
- Trial name
- LI-ESWT (NCT01262157)
- Testing
- Extracorporeal Shockwave Therapy Generator (Vascuspec), Low intensity shock wave therapy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Erectile Dysfunction
Evaluation of the Coloplast Titan® IPP for Maintaining Penile Length While Treating Erectile Dysfunction (ED)
This study is designed to assess the effectiveness of the Coloplast Titan® Inflatable Penile Prosthesis (IPP) at maintaining or increasing penile length after implantation of the device.
- Trial name
- NCT00731666
- Testing
- Inflatable Penile Prosthesis
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Coloplast A/S
Erectile Dysfunction With Diabetes Mellitus
Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction
The goal of this prospective randomized controlled clinical study is to evaluate the effectiveness and safety of intracavernosal injections of umbilical cord-derived mesenchymal stem cells (MSCs) and umbilical cord-derived…
- Trial name
- NCT07480161
- Testing
- Umbilical Cord-Derived Mesenchymal Stem Cells, Umblical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Erectile Dysfunction
Pelvic Floor Muscle Training in the Treatment of Erectile Dysfunction
Erectile dysfunction affects about 40% of all men above the age of 40 and the prevalence increases with increasing age. It is not possible to cure the condition as current forms of treatment are aimed solely at improving…
- Trial name
- NCT05385822
- Testing
- Pelvic Floor Muscle Training
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Erectile Dysfunction, Diabetes Mellitus Type 2
Umbilical Cord Mesenchymal Stem Cell Secretome Administration in Severe Erectile Dysfunction Non-responsive to Sildenafil
The study is an experimental pre-post-test design involving 12 patients with severe ED non-responsive to sildenafil. Safety parameters included pain, hematoma, local bleeding, and infection, while efficacy was measured using the…
- Trial name
- NCT07245875
- Testing
- Intracavernosal Injection of Umbilical Cord Mesenchymal Stem Cell Secretome
- Where
- Indonesia
- Volunteers
- 12 people
- Sponsor
- Universitas Indonesia
Erectile Dysfunction
A Double-blind "Preferred" Vardenafil Dose Study of QoL and Functional Outcomes in Males With Erectile Dysfunction
To find out more information on how treating impotence with vardenafil in comparison to placebo affects the quality of life (QoL) of men and their partners.
- Trial name
- NCT00661700
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 23 sites in Ireland, United Kingdom
- Volunteers
- 611 people
- Sponsor
- Bayer
Erectile Dysfunction
Penile Prosthesis in Patients With Erectile Dysfunction
Erectile dysfunction (ED) is defined as the persistent inability to attain and or maintain an erection sufficient to permit satisfactory sexual performance
- Trial name
- NCT03466619
- Testing
- inflatable penile prosthesis (IPP)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Erectile Dysfunction, Renal Transplant
Extracorporeal Shockwave Therapy in the Treatment for Erectile Dysfunction in Male Renal Transplant Recipients
The primary objective of this study is to determine the impact of the shock wave application in renal transplant patients with diagnosis of erectile dysfunction.
- Trial name
- NCT02412345
- Testing
- Extracorporeal shockwave therapy, Penile ultrasound Doppler with intracavernosal injection application 20 mcg alprostadil
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Testis Cancer, Cognitive Impairment
Mental Health of Men Before and After Testicular Cancer Treatment
This is a prospective observational study, that investigates men diagnosed with testicular cancer before and after treatment. The patients are included at their visit at the Fertility clinic in Horsens, where they deposit semen…
- Conditions
- Testis Cancer, Cognitive Impairment, Sexual Dysfunction
- Trial name
- NCT03880994
- Where
- Denmark
- Volunteers
- 29 people
- Sponsor
- University of Aarhus
Impotence
Safety and Clinical Effectiveness of 2 Lower Dose Combined PDE5i's vs. Single Maximal Dose PDE5i
A prospective, randomized, 3-arm parallel trial on 45 males with ED that were never exposed to PDE5i therapy (naïve patients) will be enrolled.In each group, every patient will receive three treatment regimes (Viagra®50mg \&…
- Trial name
- NCT00498680
- Testing
- Sildenafil, Vardenafil, Sildenafil, Vardenafil
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Rambam Health Care Campus
Erectile Dysfunction
A Thorough EKG Safety Study of TA-1790 (Avanafil)
This study is to assess whether treatment with a therapeutic (100 mg) or supratherapeutic (800 mg) dose of avanafil has the potential to cause QT/QTc prolongation in healthy volunteers.
- Trial name
- NCT00769041
- Testing
- moxifloxacin, avanafil, sugar pill
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Erectile Dysfunction Due to Arterial Insufficiency
PRP Exosomes Therapy for Erectile Dysfunction
It will be a Single-arm, single-center, feasibility clinical trial with Primary Objective to investigate the treatment efficacy of PRP-derived exosomes injection in men with mild-moderate vasculogenic ED, as measured by the…
- Trial name
- NCT07124871
- Testing
- PRP-derived exosomes injection
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece
Erectile Dysfunction
A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation
The primary purpose of the study is to demonstrate that dapoxetine can prolong intravaginal ejaculatory latency time (IELT) compared with placebo in men with premature ejaculation (PE).
- Trial name
- NCT00210704
- Testing
- Dapoxetine
- Volunteers
- 1,067 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Hypertension, Ventricular Remodeling
Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Patients With Slight Hypertension and Target Organ Damage
Patients with slight increase in blood pressure levels have an increased cardiovascular risk. In particular this has been demonstrated also in subjects with high-normal blood pressure in whom an exaggerated blood pressure…
- Conditions
- Hypertension, Ventricular Remodeling, Erectile Dysfunctions
- Trial name
- NCT00687206
- Testing
- Valsartan 160mg plus HCT 25mg
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Secondary Hypogonadism, Sexual Dysfunction
Safety and Efficacy Study of Oral Fispemifene for the Treatment of Sexual Dysfunction in Hypogonadal Men
To evaluate the safety and efficacy of fispemifene in men with secondary hypogonadism and sexual side effects.
- Conditions
- Secondary Hypogonadism, Sexual Dysfunction, Erectile Dysfunction
- Trial name
- NCT02443090
- Testing
- fispemifene
- Where
- 16 sites in United States
- Volunteers
- 160 people
- Sponsor
- NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences, Inc.)
Impotence, Prostate Cancer
Evaluate the Effects of GPI 1485 on Erectile Function Following Bilateral Nerve-Sparing Prostatectomy
In this phase II study, an investigative (not approved by the FDA) drug called GPI 1485 is being assessed to see if it can help preserve erectile function after prostatectomy.
- Trial name
- NCT00090376
- Testing
- GPI 1485
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Eisai Inc.
Obstructive Sleep Apnea, Erectile Dysfunction
Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response?
The problems like metabolic syndrome and sexual impotence in males with obstructive sleep apnea are common. continuous passive airway pressure (CPAP) is an authorized treatment for this type of apnea but still the recommendations…
- Conditions
- Obstructive Sleep Apnea, Erectile Dysfunction, Metabolic Syndrome
- Trial name
- NCT06960746
- Testing
- lifestyle changing plus CPAP, CPAP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University