Clinical trials: Male Erectile Dysfunction
Hypogonadism, Male, Secondary Hypogonadism
AIM-TEST: Microbiome-Targeted Nutrition for Functional Secondary Hypogonadism
AIM-TEST is a randomized, double-blind, placebo-controlled clinical trial evaluating whether an AI-guided, microbiome-targeted nutritional intervention can increase the body's own testosterone production in men aged 30-65 years…
- Trial name
- AIM-TEST (NCT07761546)
- Testing
- Fixed-Formula Microbiome-Targeted Oral Nutritional Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Varol TUNALI
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Hypogonadism, Metabolic Syndrome
Testosterone Replacement in Metabolic Syndrome and Inflammation
Hypogonadism (HG) frequently complicates the Metabolic Syndrome (MetS), whether testosterone replacement (TRT) is beneficial has not been clearly ascertained.
- Conditions
- Hypogonadism, Metabolic Syndrome, Obesity, Erectile Dysfunction
- Trial name
- TERMSINFAT (NCT01123278)
- Testing
- Testosterone
- Where
- 2 sites in Italy
- Volunteers
- 82 people
- Sponsor
- University of Roma La Sapienza
Erectile Dysfunction
Drug Interaction Study of Avanafil and Enalapril or Amlodipine
The purpose of this study is to determine the change in the blood pressure and pulse rate, pharmacokinetics and the safety when avanafil is taken with either enalapril or amlodipine.
- Trial name
- NCT01117038
- Testing
- avanafil and enalapril, avanafil and amlodipine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Erectile Dysfunction
Differential Plasma MicroRNA Profiles in ED and Normal Erectile Function in Older Males
Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come.
- Trial name
- NCT01830049
- Testing
- Take blood
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Erectile Dysfunction
Effect of Intradialytic Exercise on Erectile Dysfunction in Hemodialysis Men
This study aimed to assess the effect of IDEP on ED and its associated psychological burden in HD men. Forty HD men with ED were randomly assigned into the IDEP group (this group contained 20 HD men with ED who received…
- Trial name
- IDEP (NCT06635044)
- Testing
- intradialytic exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mohammed Mohamed Mazen
Erectile Dysfunction
LiST Plus PRP Injection Therapy vs LiST Monotherapy for ED Treatment
We designed a double blind randomized sham-controlled trial in order to investigate and compare the treatment efficacy of LiST plus PRP intracorporeal injection vs LiST plus placebo (normal saline intracorporeal injection) in men…
- Trial name
- NCT05366504
- Testing
- LiST + PRP intracorporeal injection
- Volunteers
- 60 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece
Erectile Dysfunction, Sexual Dysfunction
Real-world Longitudinal Follow-up Study of a Digital Health Application in Erectile Dysfunction
The goal of this observational study is to assess the long-term effectiveness of a digital health application for treating erectile dysfunction in men aged 18 and older.
- Trial name
- RELOED (NCT06501144)
- Where
- Germany
- Volunteers
- 317 people
- Sponsor
- Kranus Health GmbH
Erectile Dysfunction
Assessment of Duration of Erection With Vardenafil 10 mg
This study assessed the effect of 10mg vardenafil, taken on demand in an 'at home' setting, as compared to placebo (dummy medication with no pharmacological activity), on the duration of erection from the moment when the patient…
- Trial name
- NCT00663728
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Volunteers
- 201 people
- Sponsor
- Bayer
Erectile Dysfunction
A Study to Investigate the Time to Onset of Action of 10 mg and 20 mg of Vardenafil Compared to Placebo in Males With Erectile Dysfunction
This purpose of the study was to evaluate the earliest time to onset of action in adults with erectile dysfunction (often called impotence). In this study vardenafil has been compared to placebo.
- Trial name
- NCT00665496
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 75 sites in United States, Canada and 9 more
- Volunteers
- 732 people
- Sponsor
- Bayer
Erectile Dysfunction
Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction
Researchers are evaluating the efficacy of low intensity shockwave therapy (LISWT) via MoreNova in the treatment of erectile dysfunction (ED).
- Trial name
- NCT04136288
- Testing
- MoreNova
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Rectal Tumors, Erectile Dysfunction
Early Intervention for Erectile Dysfunction After Laparoscopic Resection for Rectal Cancer
Although the high prevalence of erectile dysfunction (ED) was detected among male patients after the treatment for colorectal cancer, published reports depicting the erectile dysfunction experience of patients with colorectal…
- Trial name
- NCT01912586
- Testing
- vacuum erection device
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Erectile Dysfunction
Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of Mild to Moderate ED
Prospective, open-label, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of mild to…
- Trial name
- PMD-MSC-ED-01 (NCT02398370)
- Testing
- Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Melissa Marchand
Erectile Dysfunction (ED), Erectile Dysfunctions
A Single-Arm, Dose Escalation of an Intraurethral Alprostadil Paste for Erectile Dysfunction
This is a single arm dose escalation trial of a mucoadhesive intraurethral polymer suspension of alprostadil (ST-04) and will investigate the efficacy of 3 dose levels of ST-04 in adult males with a clinical diagnosis of Erectile…
- Conditions
- Erectile Dysfunction (ED), Erectile Dysfunctions, Erectile Function
- Trial name
- NCT07601646
- Testing
- ST-04
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Ryan Flannigan, MD
Erectile Dysfunction Following Radical Prostatectomy
MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction
The investigators are doing this research to evaluate the efficacy and safety of topical MED3000 therapy in men with persistent erectile dysfunction 1.5 to 4 years following radical prostatectomy surgery.
- Trial name
- NCT05673005
- Testing
- MED3000 topical gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Impotence
Use of Sildenafil (Viagra) in Diabetic Men With Erectile Dysfunction: the Impact on Blood Vessels
To evaluate the impact of nightly sildenafil vs placebo use on diabetic men with and without proven endothelial dysfunction and coexisting erectile concerns.
- Trial name
- NCT00199563
- Testing
- Viagra
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Regenerative Injection of Stem Cells or Stem Cell-derived Exosomes for Erectile Dysfunction (RISE)
The goal of this prospective observational study is to evaluate whether injections of stem cells derived from the patient's own fat tissue (adipose tissue) can improve erectile function in men aged 30 to 75 who have erectile…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- RISE (NCT06605508)
- Testing
- Autologous Adipose Tissue-Derived Stem Cell Injection for Erectile Dysfunction, Stem cell-derived Exosomes Injection for Erectile Dysfunction
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Jumeirah American Clinic
Erectile Dysfunction
A Study to Assess the Efficacy and Safety of Vardenafil in the Treatment of Male Patients With Erectile Dysfunction
The primary objective of this study is to assess the efficacy together with safety of a flexible regimen, for a period of twelve weeks, of three doses (5 mg, 10mg and 20mg) of Bay 38-9456, a phosphodiesterase type V inhibitor, in…
- Trial name
- VIS (NCT00654914)
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Volunteers
- 527 people
- Sponsor
- Bayer
Erectile Dysfunction
Long-Term Safety and Efficacy Study of Avanafil in Men With Erectile Dysfunction
This open-label study is being conducted to evaluate the long-term safety, tolerability, and efficacy of avanafil in men with mild to severe erectile dysfunction.
- Trial name
- NCT00853606
- Testing
- avanafil
- Where
- 40 sites in United States
- Volunteers
- 712 people
- Sponsor
- VIVUS LLC
Erectile Dysfunction
A Study to Compare the Blood Levels of Sildenafil Following Administration of an Experimental Tablet vs. the Conventional Oral Tablet in Healthy Subjects
This study to will compare the blood levels of sildenafil following administration of an experimental tablet vs. the conventional oral tablet.
- Trial name
- NCT00866463
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.