Clinical trials: Male-factor Infertility
Infertility
Eeva 12-well Dish Study
The purpose of this study is to demonstrate that the Eeva™ System is compatible with the Eeva 12-well Dish.
- Trial name
- NDS (NCT01635036)
- Testing
- In-vitro fertilization using Eeva
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Progyny, Inc.
Male Factor Infertility
Effectiveness of the Use of the PICSI Dish (Hyaluronan Microdot) in the Selection of Sperm for Intracytoplasmic Sperm Injection (ICSI)
The purpose of this study is to determine if using microdots of hyaluronan (PICSI) to select sperm for ICSI will result in increased pregnancies especially with men that have a low hyaluronan binding score (HBA).
- Trial name
- NCT00741494
- Testing
- PICSI dish
- Where
- 9 sites in United States
- Volunteers
- 801 people
- Sponsor
- Biocoat
Infertility, Male, IVF
BPA Levels Relationship With IVF/ICSI Outcomes in Patients With Male Factor
Association between blood and semen BPA levels and ICSI outcomes in patients with male factor
- Trial name
- NCT05224284
- Testing
- BPA levels
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Conventional IVF, ICSI
Child Follow-up in Women Treated With Conventional IVF or ICSI
To compare the physical, mental and motor development of babies born from pregnancy using ICSI technique and and conventional IVF in non-male factor infertile couples.
- Trial name
- NCT04866524
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 322 people
- Sponsor
- Mỹ Đức Hospital
PCOS, Endometriosis
Pomegranate Juice Effect on Oxidative Stress in Infertile Women During IVF Treatment
tTe investigators estimate pomegranate supplementation effect on oxidative stress in infertile women with PCOS, endometriosis and advanced maternal age during IVF treatment.
- Conditions
- PCOS, Endometriosis, Advised Maternal Age, Male Factor Infertility
- Trial name
- NCT03978013
- Testing
- Pomegranate juice, Apple juice
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Infertility, Male, Varicocele
IVF Outcomes After Varicocele Repair
Infertility has been estimated to affect from 6-18% of couples trying to conceive. In 20-30% of cases, the problem is with the male.
- Conditions
- Infertility, Male, Varicocele, In Vitro Fertilization
- Trial name
- NCT03090438
- Testing
- Varicocele embolization
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Infertility
Use of a Calcium Channel Blocker to Prevent Premature Luteinizing Hormone Surges in Infertility Patients
Nimodipine (Nimotop® Bayer Pharmaceuticals Corporation), unlike other calcium channel blockers is fat soluble and therefore is able to cross the blood-brain barrier1.
- Trial name
- nimodipine (NCT01551368)
- Testing
- Nimodipine
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Mount Sinai Hospital, Canada
Infertility
Safety and Efficacy of Freezing and Thawing of Human Eggs in Assisted Reproductive Technology
The purpose of this study is to determine the effectiveness of the ViaCell's product media for freezing and thawing human eggs for future use in assisted reproductive technology.
- Trial name
- NCT00451009
- Testing
- Viacell's product Media Kits
- Where
- 4 sites in United States
- Sponsor
- ViaCell
Infertility
The Role of Massage in Increasing Total Motile Sperm Count of IUI
The purpose of this prospective, randomized study, was to determine if neck and shoulder massage performed within 15 minutes of semen sample collection will increase the semen volume, and therefore increase the total motile sperm…
- Trial name
- NCT01969825
- Testing
- Massage
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Oligoasthenoteratozoospermia
Severe Male Factor Infertility Management
This study is the first to evaluate the effect of oral supplementation with antioxidants combined with lifestyle modification for severe male factor partner of couples undergoing ICSI.
- Trial name
- OAT (NCT02752555)
- Testing
- Antioxidant (l-cratinine) + modifiable lifestyle factors
- Where
- 3 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Assisted Reproductive Technology, Assisted Reproductive Technology Outcomes
Sperm Selection Strategies and Male-Factor Phenotypes in ICSI
This retrospective multicentre observational cohort study evaluates clinical and reproductive outcomes associated with different sperm-selection strategies used during intracytoplasmic sperm injection (ICSI), including…
- Trial name
- ANDRO-ART (NCT07825584)
- Testing
- Conventional ICSI, Hyaluronan-Binding Sperm Selection, ZyMōt
- Where
- 10 sites in Poland
- Volunteers
- 12,561 people
- Sponsor
- Center for Reproductive Medicine Bocian
Male-factor Infertility
Understanding Adaptive Challenges Associated With Male-factor Infertility
The purpose of this study is to understand the experience of men and their partners when diagnosed with male-factor infertility while trying to achieve a pregnancy and the skills they use to adapt to this diagnosis.
- Trial name
- NCT02607098
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 24 people
- Sponsor
- Duke University
In Vitro Fertilization, Infertility Assisted Reproductive Technology
Assessment of Reproductive Outcomes in Non-Male Factor Infertility Patients: Conventional in Vitro Fertilisation Versus Intracytoplasmic Sperm Injection
The aim of this clinical trial is to evaluate the efficiency of two fertilization techniques used in Assisted Reproduction: conventional In Vitro fertilization (cIVF) and Intracytoplasmic Sperm Injection (ICSI), in terms of…
- Trial name
- NCT06670586
- Testing
- conventional in vitro fertilization, intracytoplasmic sperm injection (ICSI)
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Maria Dolores Cuquerella Fernandez-Vazquez
Embryo Aneuploidies, Implantation Rates
Preimplantation Genetic Screening (PGS) in Advanced Female Age and Male Severe Factor
Preimplantation Genetic Screening (PGS) is used for the selection of chromosomally normal embryos before the transfer in IVF treatments in many cases.
- Conditions
- Embryo Aneuploidies, Implantation Rates, Infertility
- Trial name
- NCT01571076
- Testing
- PGS, Prolonged culture
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Igenomix
Infertility, Male
Outcomes of Intra-Cytoplasmic Sperm Injection in Infertile Men With Non-tense Vaginal Hydrocele
Infertile men due to oligoasthenospermia with non-tense hydroceles are subjected to ICSI
- Trial name
- NCT03532386
- Testing
- ICSI
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Male Factor Infertility
Double vs Single Intrauterine Insemination in Male Factor Infertility
The aim of the study is to compare the pregnancy outcomes of single vs double intrauterine insemination (IUI) in couples with male factor infertility.
- Trial name
- NCT05885516
- Testing
- intrauterine insemination
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Male Infertility, Infertility, Male
The Evaluation of the Effect of Microfluidic Sperm Sorting Chip 'Labs-on-a-chip' on IVF Success in Male Factor
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT03960229
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility Due to Azoospermia
PKB171 Against Placebo in Couples With Mild Male Factor Infertility
The test medication Gel PKB171 is a vaginal gel that has not yet been licensed by the regulatory authorities. However, the active substance pentoxifylline has been available as tablets for decades and is used to increase…
- Trial name
- NCT07669584
- Testing
- Intravaginal gel, Vaginal Gel with Applicator
- Where
- 12 sites in Spain
- Volunteers
- 732 people
- Sponsor
- Prokrea BCN, S.L.
Infertility, Female, ART
Intracytoplasmic Sperm Injection in Non-male Factor Infertility in Advanced Maternal Age
This will be a prospective, randomized (1:1 ratio) clinical trial for non-male factor infertility in advanced maternal age with or without intracytoplasmic sperm injection(ICSI).
- Trial name
- NCT03120884
- Testing
- ICSI, IVF
- Where
- China
- Volunteers
- 1,422 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Infertility, Male Factor Infertility
A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence
This research is being done to determine if producing sperm after an ultrashort period of abstinence (1 hour of abstinence) will be effective in improving the rates of embryos with normal chromosomes (structures that carry…
- Trial name
- NCT07062237
- Testing
- Ultrashort abstinence, Standard abstinence
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- UConn Health