Clinical trials: Malignant Gastric Outlet Obstruction
Duodenal Obstruction, Gastric Outlet Obstruction
EVOLUTION® Duodenal Stent for Duodenal or Gastric Outlet Obstruction Caused by Malignant Neoplasms
The objective of this investigation is to compile clinical experience on the use of the Evolution® Duodenal Stent (Cook Ireland), a CE marked device intended for the palliative treatment of duodenal or gastric outlet obstruction…
- Trial name
- NCT00991614
- Testing
- EVOLUTION® Duodenal Stent
- Where
- 6 sites in Australia, Canada and 3 more
- Volunteers
- 110 people
- Sponsor
- Cook Group Incorporated
Gastric Cancer, Gastric Outlet Obstruction
Stomach-Partitioning Versus Conventional Gastrojejunostomy for Malignant Gastric Outlet Obstruction: A Multicenter Randomized Controlled Trial
Gastric outlet obstruction (GOO) complicates locally advanced or metastatic gastric cancer and severely impairs oral intake, nutritional status, and quality of life.
- Trial name
- NCT07561073
- Testing
- stomach-partitioning gastrojejunostomy, conventional gastrojejunostomy
- Where
- 3 sites in China
- Volunteers
- 80 people
- Sponsor
- Guangxi Medical University
Malignant Gastric Outlet Obstruction
Endoscopic Ultrasound-guided Versus Surgical Gastroenterostomy for Malignant Gastric Outlet Obstruction
Gastric outlet obstruction (GOO), defined by a mechanical obstruction of the duodenum, pylorus, or antrum, may result from various diseases.
- Trial name
- NCT05564143
- Testing
- EUS-guided gastroenterostomy (EUS-GE), Laparoscopic gastroenterostomy (LGE)
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Malignant Gastric Outlet Obstruction
Endoscopic Ultrasound-Guided Gastroenterostomy for Malignant Gastric Outlet Obstruction
Malignant gastric outlet obstruction is a very disabling complication of patients with gastric, duodenal, ampullary, pancreatic, or bile duct cancer and worsens their prognosis.
- Trial name
- NCT04810377
- Testing
- EUS-guided gastroenterostomy
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Stomach Neoplasms, Gastric Outlet Obstruction
Malignant Gastric Outlet Obstruction Study With Stomach Partitioning (GO-PART)
The goal of this clinical trial is to evaluate whether stomach-partitioning gastrojejunostomy (SPGJ) more effectively reduces postoperative delayed gastric emptying (DGE) compared to conventional gastrojejunostomy (CGJ) in…
- Trial name
- GO-PART (NCT07749326)
- Testing
- Conventional Gastrojejunostomy, Stomach-Partitioning
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Gyeongsang National University Hospital
Malignant Biliary Obstruction
Palliation of Gastric Outflow Obstruction in Case of Concomitant Biliary Obstruction.
EUS-guided drainages has been largely widespread during the last 10 years, even thanks to the advent of dedicated devices, such as lumen apposing metal stents (LAMSs).
- Trial name
- B-GOOD (NCT05142839)
- Testing
- EUS-CD, EUS-GEA
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Istituto Clinico Humanitas
Malignant Gastric Outlet Obstruction
The Usefulness of Self-expandable Metal Stents(SEMS) for Malignant Gastric Outlet Obstruction: a Prospective Study Using New Designed Stents
The purpose of this study is to evaluate usefulness of new designed winged stent(SEMS).
- Trial name
- SEMS (NCT02440724)
- Testing
- Winged stent (partially covered), Winged stent (uncovered)
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Asan Medical Center
Malignant Small Bowel Obstruction, Malignant Gastric Outlet Obstruction
AspireAssist for Palliative Venting Gastrostomy in Malignant Bowel Obstruction Patients
Individuals with cancer causing an intestinal or stomach obstruction often require gastric drainage to prevent symptoms of nausea, vomiting, and to prevent aspiration.
- Trial name
- NCT04375462
- Testing
- AspireAssist device, Standard decompressive PEG tube, gastric outlet obstruction scoring system (GOOSS) questionnaire
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Gastric Outlet Obstruction
EUS-GE vs ES for Palliation of Gastric Outlet Obstruction
Gastric outlet obstruction (GOO) is a common complication of luminal malignancies which is associated with substantial morbidity.
- Trial name
- NCT03259763
- Testing
- Lumen-apposing metal stent, Self-expandable metal stent
- Where
- 9 sites in United States, Canada and 5 more
- Volunteers
- 112 people
- Sponsor
- Johns Hopkins University
Gastric Outlet Obstruction, Pancreatic Cancer
Management of Malignant Gastric Outlet Obstruction Between Surgery and Endoscopy
The aim of this observational study is to compare the outcomes of three different procedures performed for the management of malignant Gastric Outlet Obstruction due to Pancreatic Cancer.
- Trial name
- GOOSE (NCT06071507)
- Where
- 5 sites in France, Italy and 2 more
- Volunteers
- 250 people
- Sponsor
- IRCCS San Raffaele
B Cell Lymphoma, NHL, Adult
SynKIR-310 for Relapsed/Refractory B-NHL
This first-in-human (FIH) trial is designed to assess the safety, feasibility and preliminary efficacy of a single intravenous (IV) dose of SynKIR-310 administered to participants with relapsed/refractory B-NHL.
- Conditions
- B Cell Lymphoma, NHL, Adult, Mantle Cell Lymphoma, Relapsed Non-Hodgkin Lymphoma
- Trial name
- NCT06544265
- Testing
- SynKIR-310
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Verismo Therapeutics
Gastric Outlet Obstruction Due to Gastric Adenocarcinoma
Covered Versus Uncovered Self-expandable Metallic Stents for Malignant Gastric Outlet Obstruction
Malignant gastric outlet obstruction can result from gastric adenocarcinoma, leading to intractable vomiting, nausea, and poor oral food intake.
- Trial name
- NCT01646476
- Testing
- Covered stent (Bona stent pyloric/duodenal covered) insertion, Uncovered stent (Bona stent, pyloric/duodenal) insertion
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- Samsung Medical Center
Gastric Outlet Obstruction
EUS - Guided Balloon-occluded Gastrojejunostomy Bypass
Surgical gastrojejunostomy is the conventional treatment for palliating patients suffering from of inoperable malignant gastric outlet obstruction (GOO).
- Trial name
- NCT03223480
- Testing
- EUS-guided gastrojejunstomy
- Where
- Hong Kong
- Volunteers
- 14 people
- Sponsor
- Chinese University of Hong Kong