Clinical trials: Malignant Neoplasm of Abdomen
Abdominal Tumor, Abdominal Infection
Evaluation of Pcv-aCO2 in the Fluid Treatment of Abdominal Tumor Patients After Surgery
This research will confirm that Pcv-aCO2 is suitable for the guidance of early fluid therapy and the evaluation of the prognosis of patients with abnormal hemodynamics after abdominal tumor surgery, and is expected to be a new…
- Trial name
- NCT02977429
- Testing
- standardized fluid therapy, conventional fluid therapy
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Abdominal Cancer, Lung Cancer
A Feasibility Study of MRI Guided Stereotactic Ablative Radiotherapy (MIDSECTION)
To determine if the investigators are able to deliver highly focused, intense radiation to tumours in the abdominal region or chest cavity whilst limiting the dose to surrounding organs using a high field strength MR-Linac.
- Trial name
- MIDSECTION (NCT05903430)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- The Christie NHS Foundation Trust
B7-H3-positive Advanced Malignant Solid Tumors Advanced Primary Peritoneal Tumors or Secondary Abdominal Metastatic Malignant Solid Tumors
MT027 in Patients With Advanced Peritoneal Malignancies or Abdominal Metastatic Solid Tumors
This is an open-label, single-arm phase I dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetic profile, and preliminary efficacy of MT027 in patients with advanced primary peritoneal malignancies…
- Trial name
- NCT06912152
- Testing
- MT027 CAR-T cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Zhejiang University
Malignant Neoplasm of Abdomen, Surgery
TAP Versus Thoracic Epidural in Major Abdominal Resections
The purpose of this study is to compare two standard methods of pain control management used at Spectrum Health for patients undergoing major surgery. The two methods being compared are the thoracic epidural and the TAP block.
- Trial name
- NCT02197988
- Testing
- Exparel 1.33% (20ml Volume), 0.125% bupivicaine with 2 mcg/ml Fentanyl.
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Corewell Health West
Cancer, Abdominal Cancer Surgery
Developing Pilot Postoperative Guidelines for Improved Functional Outcomes After High-Risk Cancer Surgery
The objective of this study is to develop and evaluate the implementation of novel timeline-specific National Comprehensive Cancer Network (NCCN)-style clinical guidelines designed to improve functional outcomes after high-risk…
- Conditions
- Cancer, Abdominal Cancer Surgery, Surgery, Recovery Outcomes
- Trial name
- NCT07720089
- Testing
- Algorithmic Guideline for Functional Recovery following Cancer Surgery
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Alabama at Birmingham
Cancer
Interleukin-12 in Treating Patients With Refractory Advanced-Stage Ovarian Cancer or Abdominal Cancer
Phase I trial to study the effectiveness of interleukin-12 in treating patients with refractory ovarian or abdominal cancers. Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a persons's…
- Trial name
- NCT00003439
- Testing
- recombinant interleukin-12
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Cancer Institute (NCI)
PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics
Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated…
- Trial name
- NCT07550738
- Testing
- electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Immune System
Immunologic Effect of Fraction of Inspired Oxygen
During anesthesia and surgery, oxygen is routinely administered to all patients. Inspired oxygen concentrations, however, vary between 30% - 100% and oxygen is often administered in a seemingly random manner.
- Trial name
- NCT04772794
- Testing
- fraction of inspired oxygen
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Neoplasms Malignant, Surgery
Improved Adherence With Extended Venous Thromboembolism Prophylaxis After Major Cancer Surgery
This is a prospective, twin-center, cohort study in patients discharged from the hospital after major abdominal or pelvic cancer surgery for cancer.
- Conditions
- Neoplasms Malignant, Surgery, Venous Thromboembolism, Prophylaxis
- Trial name
- NCT04479579
- Testing
- Apixaban 2.5 milligram
- Where
- 2 sites in Canada
- Volunteers
- 53 people
- Sponsor
- McMaster University
Pheochromocytoma Malignant
Abdominal Circumference as a Predictor of Operative Time in Retroperitoneal Adrenalectomy for Pheochromocytoma
This retrospective observational study examines whether abdominal circumference is associated with operative time in patients undergoing retroperitoneal adrenalectomy for pheochromocytoma.
- Trial name
- NCT07339241
- Testing
- Retroperitoneal Adrenalectomy
- Volunteers
- 159 people
- Sponsor
- Asan Medical Center
Cancer Pain
Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer Pain
This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and…
- Trial name
- NCT07445386
- Testing
- transdiscal splanchnic neurolysis, paravertebral splanchnic neurolysis
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Pain
Erector Spinae vs TAP in Lower Abdominal Surgery
The aim of this study is to compare the analgesic effect and safety profile of erector spinae plane block with transverses abdominis plane block in controlling peri-operative pain for lower abdominal cancer surgery.
- Trial name
- NCT04555993
- Testing
- lower abdominal surgery, Erector spinae plane block, Transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- National Cancer Institute, Egypt
Gastric Cancer, Lung Cancer
Evaluation of Respiratory Motion-Corrected Cone-Beam CT in Radiation Treatment of Thoracic and Abdominal Cancers
Tumors must be seen clearly on CT scan to be radiated completely and safely. Breathing causes tumors to move. If the tumor moves during breathing, it can look blurred on the CT scan. This makes it difficult to see on CT scan.
- Trial name
- NCT01213004
- Testing
- respiration correlated CT scan
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Abdominal Cancer, Thoracic Cancer
Teleprehabilitation for Surgical Cancer Patients
There is a general concern that the backlog of cancer patients waiting for surgery during this period is going to increase and the general impact on patients isolated in their homes is going to cause potential physiological and…
- Trial name
- NCT04799561
- Testing
- Multimodal Teleprehabilitation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
To Compare Efficacy of Dexmedetomidine in Bilateral Quadratus Lumborum vs Lumbar Epidural Blocks on Analgesia After Major Lower Abdominal Surgery
Clinical Efficacy and Safety of Dexmedetomidine as an Adjuvant in Quadratus Lumborum Versus Epidural Block in Postoperative Lower Abdominal Cancer Surgeries
Clinical efficacy and safety of dexmedetomidine as an adjuvant in quadratus lumborum versus epidural block in postoperative patients
- Trial name
- NCT06130670
- Testing
- nerve block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abdominal Cancer, Malignancy
Feasibility Study of Intra-Tumoral Lipopolysaccharide Immunotherapy for Intra-Abdominal Tumors
The purpose of this research study is to determine whether a sterile bacteria wall chemical, called lipopolysaccharide (LPS), can be injected safely into abdominal tumors during routine laparoscopic surgery performed as a…
- Trial name
- LPS (NCT05751837)
- Testing
- Lipopolysaccharide
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Patrick Wagner, MD, FACS
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Digital Meditation for Postoperative Pain Control After Abdominal Surgery for Cancer
This phase I trial tests a digital meditation for postoperative pain control after abdominal surgery for cancer. Mindfulness interventions such as guided meditation may improve pain control and decrease stress.
- Trial name
- NCT05346692
- Testing
- Survey Administration, Interview, Text Message-Based Navigation Intervention
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Emory University
Abdominal Cancer
Tidal Volume Challenge and Reliability of Plethysmography Variability Index
The aim of this study is to investigate whether a temporary increase in tidal volume can predict fluid responsiveness in patients receiving a low tidal volume ventilation in hepatobiliary and pancreatic surgeries.
- Trial name
- NCT03546179
- Testing
- tidal volume challenge test, Volume loading
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Fayoum University Hospital
Anal Cancer, Carcinoma of the Appendix
Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer
RATIONALE: Palonosetron hydrochloride may prevent nausea and vomiting caused by radiation therapy. It is not yet known whether palonosetron hydrochloride is more effective than a placebo in preventing nausea and vomiting.
- Conditions
- Anal Cancer, Carcinoma of the Appendix, Colorectal Cancer, Extrahepatic Bile Duct Cancer
- Trial name
- NCT00903396
- Testing
- palonosetron hydrochloride
- Where
- 69 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Compliance, Abdominal Cancer
Improvement of Compliance for High Doses of EPA Amongst Patients With Colorectal Cancer
Several studies indicate beneficial effects of eicosapentanoic acid (EPA) on cancer cachexia. However, compliance is generally low.
- Trial name
- NCT03751384
- Testing
- Möllers Omega-3 Ekstra Sterk, Nutrifriend Cachexia
- Where
- Denmark
- Volunteers
- 41 people
- Sponsor
- University of Copenhagen