Clinical trials: Malignant Neoplasm of Female Breast
Breast Cancer Female, Overweight and Obesity
Lifestyle Behavioural Intervention on Breast Cancer Survivors for the Treatment of Overweight/Obesity.
The goal of this clinical trial is to compare a behavioural lifestyle intervention program (BL) to usual care (UC) in breast cancer survivors. The main questions it aims to answer are: 1.
- Trial name
- Nutri-Life (NCT06577545)
- Testing
- Behavioural Lifestyle (BL)
- Where
- Greece
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Solid Tumor, Triple-negative Breast Cancer
A Study of LY3435151 in Participants With Solid Tumors
The reason for this study is to see if the study drug LY3435151 is safe in participants with advanced solid tumors.
- Conditions
- Solid Tumor, Triple-negative Breast Cancer, Gastric Adenocarcinoma, Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT04099277
- Testing
- LY3435151, Pembrolizumab
- Where
- 2 sites in United States, Japan
- Volunteers
- 2 people
- Sponsor
- Eli Lilly and Company
Metastatic Cancer
Genetically-informed Therapies for Patients With Metastatic Cancer
Genetic mutations associated with cancer are being discovered and new treatments are being created to treat people whose cancer tumors have certain genetic mutations.
- Trial name
- GENIUS (NCT02000739)
- Testing
- Genetically Informed Therapy
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Fear of Cancer Recurrence, Breast Cancer Female
ConquerFear-Group: A Psychological Intervention for Fear of Cancer Recurrence
The primary aim of this randomized controlled trial is to evaluate the effect of ConquerFear-Group (CF-G), compared with a control condition (CC), on Fear of Cancer Recurrence (FCR).
- Trial name
- NCT04137575
- Testing
- ConquerFear-Group, Relaxation Training
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Aarhus University Hospital
Breast Carcinoma
Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients
This study evaluates endocrine therapy-induced alopecia among postmenopausal and premenopausal female patients with breast cancer.
- Trial name
- NCT05612100
- Testing
- Electronic Health Record Review, Questionnaire Administration, Survey Administration
- Where
- 23 sites in United States
- Volunteers
- 169 people
- Sponsor
- Mayo Clinic
Prostate Cancer, Breast Cancer Female
Streaming Web-based Exercise At Home: A Pilot Study
This is a single-arm pilot study to evaluate the use of web-based video conferencing as a method of exercise training delivery. This study will include 10 female breast cancer survivors and 10 male prostate cancer survivors.
- Trial name
- NCT04282967
- Testing
- Exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Celina Shirazipour
Cervical Cancer, Breast Cancer
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
A Phase 1 Open-Label, First-in-human, Dose Escalation and Expansion Study to Determine the Safety, Tolerability, Dosimetry, Pharmacokinetics, and Preliminary Efficacy of 212Pb-DOTAM-GRPR1 in Adult Participants with Recurrent or…
- Conditions
- Cervical Cancer, Breast Cancer, Colon Cancer, NSCLC
- Trial name
- NCT05283330
- Testing
- ²¹²Pb-DOTAM-GRPR1
- Where
- 8 sites in United States
- Volunteers
- 48 people
- Sponsor
- Orano Med Theranostics, SAS
Breast Neoplasm Malignant Female
SBRT for Breast Cancer Oligometastases
This is a prospective data collection of treatment outcome for newly diagnosed oligometastatic breast cancers with 1-3 bone metastases. Eligible patients will be identified from the weekly Breast MDC.
- Trial name
- NCT04424732
- Testing
- Stereotactic Body Radiotherapy
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- King Hussein Cancer Center
Advanced Solid Tumors
Study of Continuous OSI-906 Dosing
Multicenter, open-label, phase 1, cohort dose escalation study to determine the Maximum Tolerated Dose (MTD) on both Once Daily (QD) and Twice Daily (BID) schedules.
- Trial name
- NCT00514007
- Testing
- OSI-906
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 95 people
- Sponsor
- Astellas Pharma Inc
Female Breast Cancer, Male Breast Cancer
Silent Breast Cancer A Study of the Disease Prevalence Held by Imaging Guided Biopsies in Autopsy Specimens
The aim of this study is to define silent breast cancer prevalence in both sexes and will be held by biopsies performed in imaging suspicious areas of the breast (ecography and mammography) in cadavers without known breast cancer.
- Trial name
- SISYPHUS (NCT02480933)
- Testing
- Bilateral mastectomy, Biopsy
- Volunteers
- 768 people
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Advanced Malignant Solid Neoplasm, Clinical Stage III Cutaneous Melanoma AJCC v8
Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies
This phase Ib trial studies the side effects and best dose of selinexor when given together with several different standard chemotherapy or immunotherapy regimens in treating patients with malignancies that have spread to other…
- Conditions
- Advanced Malignant Solid Neoplasm, Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Fallopian Tube Carcinoma
- Trial name
- NCT02419495
- Testing
- Capecitabine, Carboplatin, Cyclophosphamide
- Where
- 5 sites in United States
- Volunteers
- 221 people
- Sponsor
- M.D. Anderson Cancer Center
Liver Neoplasms, Neoplasm Metastasis
Study of NS-9 in Patients With Liver Metastases
This study is to investigate the safety of NS-9 and to see how well it is tolerated in patients with cancer that has metastasized (spread) to the liver from another primary tumor.
- Conditions
- Liver Neoplasms, Neoplasm Metastasis, Local Neoplasm Recurrences
- Trial name
- NCT00094003
- Testing
- NS-9 [Poly I: Poly C]
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- NS Pharma, Inc.
Breast Cancer Female
Anatomical Landmarks for Chest Wall Perforators Used for Partial Breast Reconstruction
The aim of this 6-month proof-of-concept study is to map out the chest wall perforators in relation to anatomical landmarks for partial breast reconstruction.
- Trial name
- (LaPBrecon) (NCT07006662)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Breast Cancer, Renal Cell Carcinoma
Everolimus TDM to Predict Long Term Toxicity
Metastatic (HR-positive, HER2-negative) breast cancer (BC), advanced or unresectable neuroendocrine tumours of pancreatic (pNET), gastrointestinal or lung origin and metastatic renal cell carcinoma (mRCC) are diseases with poor…
- Conditions
- Breast Cancer, Renal Cell Carcinoma, Pancreatic Neuroendocrine Tumour, Gastrointestinal Neuroendocrine Tumour
- Trial name
- Foresight (NCT03033186)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University Medical Center
Breast Cancer Female, Metastases Breast
MicroRNAs and Prognosis in Breast Cancer
Mono-centric, observational retrospective and prospective study, designed for breast cancer patients to identify novel miRNA based biomarker able to predict metastases development in breast cancer patients.
- Trial name
- BREMIR (NCT06555354)
- Testing
- miRNA targeted analysis on breast cancer tissues, miRNA targeted analysis on plasma samples, miRNA profiling of breast cancer tissues
- Where
- Italy
- Volunteers
- 1,432 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Breast Cancer Female
Nerve Mobilization Techniques After Breast Cancer Surgery
Objective: To determine whether adding neurodynamic mobilization to early postoperative physiotherapy improves long-term shoulder disability after breast cancer surgery with axillary lymph node dissection.
- Trial name
- PT-ND-BC (NCT03250351)
- Testing
- Neural mobilization group, Control group
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- University of Alcala
Breast Cancer Female
Identification of Benign and Malignant Breast Nodules Using Ultrasound-modulated Optical Tomography: A Multicenter Study
Ultrasonic light scattering imaging is a new functional imaging technology that combines traditional B-mode ultrasound imaging and light scattering tomography (DOT).
- Trial name
- NCT06468566
- Testing
- Ultrasound light scattering imaging equipment
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xin-Wu Cui
Cancer
A Structured Walking Program or Standard Therapy in Cancer Patients Undergoing a Donor Bone Marrow Transplant
RATIONALE: A walking program may improve the ability to carry out daily activities after donor bone marrow transplant. PURPOSE: This randomized clinical trial is studying a structured walking program to see how well it works…
- Trial name
- NCT00445731
- Testing
- exercise intervention, management of therapy complications, observation
- Volunteers
- 115 people
- Sponsor
- University of Minnesota
Cancer
Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
The investigators will recruit and enroll individuals that may have the KRAS-variant or other microRNA binding site mutations to join registry studies.
- Trial name
- NCT02253251
- Testing
- KRAS-variant and microRNA binding site mutation testing
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiraKind
Breast Cancer Female, Health Knowledge, Attitudes, Practice
Faith in Action! A Church-Based Navigation Model to Increase Breast Cancer Screening in Korean Women
The purpose of this research is to develop a culturally adapted "Faith in Action!" curriculum to train lay health navigators to provide breast cancer screening navigation to Korean American women within faith-based settings and…
- Conditions
- Breast Cancer Female, Health Knowledge, Attitudes, Practice, Cancer Screening, Health Disparities
- Trial name
- NCT05298605
- Testing
- Faith in Action! Church-based Navigation Model, Control
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center