Clinical trials: Malnourishment
Covid19, Corona Virus Infection
Clinical Outcomes of High Dose Vitamin D Versus Standard Dose in COVID-19 Egyptian Patients
Vitamin D is a secosteroid hormone which may have beneficial role in reducing COVID-19 adverse outcomes by first regulating the renin angiotensin system (RAS).
- Conditions
- Covid19, Corona Virus Infection, Cytokine Storm, Vitamin D Deficiency
- Trial name
- NCT04738760
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Ain Shams University
Peritoneal Dialysis Complication, Hypoalbuminemia
The Effect of Natural Protein vs. Protein Supplements on Peritoneal Dialysis Patients
This study is a prospective open label clinical trial comparing serum albumin levels and total protein intake in the peritoneal dialysis patient population.
- Conditions
- Peritoneal Dialysis Complication, Hypoalbuminemia, Malnutrition
- Trial name
- NCT03569410
- Testing
- increased protein intake via natural foods, increase protein intake via protein supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diarrhea
Dose Escalation Study to Evaluate Oral Rotavirus Vaccine 116E Live Attenuated in Healthy Infants 8 to 20 Weeks Old
This study will be a Phase I, randomized, double blind, safety and immunogenicity trial of the Vero cell based 116E neonatal rotavirus vaccine candidate strain in healthy non-malnourished infants aged 8-20 weeks at three…
- Trial name
- NCT00439660
- Testing
- Oral Rotavirus Vaccine 116E Live Attenuated
- Where
- India
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Bharat Biotech International Limited
Osteoporosis, Vascular Calcification
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
The purpose of this study is to determine if supplemental vitamin K will reduce age-related bone loss in elderly men and women above that achieved by supplementation.
- Conditions
- Osteoporosis, Vascular Calcification, Inflammation
- Trial name
- NCT00183001
- Testing
- Vitamin K
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Environmental Enteric Dysfunction (EED), Stunting
Maternal Probiotic Intervention to Improve Gut Health-Trial II-Pakistan
Burden: Environmental Enteric Dysfunction (EED) is an enteropathic condition characterised by altered gut permeability, infiltration of immune cells, and changes in villous architecture and cell differentiation.
- Trial name
- MPIGH-II (NCT07207434)
- Testing
- Oral Vancomycin, VE818
- Where
- Pakistan
- Volunteers
- 144 people
- Sponsor
- Aga Khan University
Obesity, Vitamin D Deficiency
Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
As the use of bariatric surgery for treatment of extreme obesity adults continues to rise, clinicians must be aware of pre-existing nutritional deficiencies in overweight and obese patients.
- Trial name
- NCT01385098
- Testing
- Vitamin D3 and Calcium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vadim Sherman, MD
Chronic Kidney Disease, Peritoneal Dialysis
Effect of Protein-Restricted Diet on Nitrogen Balance and Residual Renal Function in Peritoneal Dialysis (PD) Patients
Current therapy recommendations suggest a low protein diet to preserve residual renal function (RRF) before the start of dialysis, but a higher protein intake during dialysis to prevent protein-energy wasting (PEW).
- Trial name
- NCT00633646
- Testing
- diets contained different levels of protein
- Volunteers
- 94 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Pregnancy, Autistic Disorder
Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children
The purpose of this research study is to screen for metabolic abnormalities that are maternal risk factors for having a child with autism.
- Conditions
- Pregnancy, Autistic Disorder, Folic Acid Deficiency
- Trial name
- NCT02674022
- Testing
- Prenatal supplement
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Malnutrition
Nutrition Supplementation in Hospitalized Patients
Patients with severe malnutrition risk are 7.4 times more likely to die in hospital than well-nourished patients, and carry a 30-day readmission rate of >46%.
- Trial name
- NutriSuP (NCT02632630)
- Testing
- Amino Acids w/Electrolytes in Dextrose, Ensure product, Crystalloid solutions
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Age-related Macular Degeneration, Vitamin D Deficiency
Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMD
Objectives: The investigators conducted a prospective study in Belgium with the objective to determine the proportion of subjects identified at moderate-to-high risk for AMD, based on the STARS® questionnaire, in need of…
- Trial name
- OVID-AMD (NCT04482465)
- Testing
- blood sample
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anorexia, Cachexia
A Study of Different Doses of Megestrol Acetate in Patients With AIDS Who Have Anorexia and Malnutrition
To compare the effects of megestrol acetate and placebo on body weight, anorexia, cachexia, calorie intake, and nutritional parameters of patients with a confirmed diagnosis of AIDS.
- Conditions
- Anorexia, Cachexia, HIV Infections
- Trial name
- NCT00002300
- Testing
- Megestrol acetate
- Where
- 15 sites in United States
- Sponsor
- Bristol-Myers Squibb
Vitamin A Deficiency
Using Stable Isotopes to Assess the Effectiveness of Vitamin A Supplementation in Cameroon
This is a study to evaluate the effects of vitamin A supplementation program on the vitamin A status of preschool children. All children aged 3-5 years who do not have severe illness and are not planning to move from the study…
- Trial name
- NCT03383744
- Testing
- vitamin A supplementation
- Volunteers
- 104 people
- Sponsor
- Centre for Food and Nutrition Research, Yaounde
Severe Acute Malnutrition
Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition
The investigators propose a pilot randomized controlled trial to train mothers to screen their children post-discharge for relapse based on MUAC criteria to facilitate timely identification and referral to care for children who…
- Trial name
- NCT05932992
- Testing
- Mother education on how to perform MUAC assessment
- Where
- Burkina Faso
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Arterial Hypertension, Vitamin D Deficiency
Styrian Vitamin D Hypertension Trial
In this randomized, double-blind, placebo-controlled trial we plan to enrol 200 vitamin D deficient hypertensive patients. Our main objective is to evaluate whether vitamin D3 supplementation with 2,800 IU daily for 8 weeks has…
- Trial name
- NCT02136771
- Testing
- Vitamin D3
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Graz
Chronic Obstructive Pulmonary Disease(COPD), Malnutrition
Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD
Insufficient energy intake and systematic inflammation lead to malnutrition in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02197871
- Testing
- enteral nutrition emulsion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital
Undernutrition
Prevalence of Undernutrition in Assiut University Children Hospital
To describe the prevalence of undernutrition in infants and children admitted to Assiut university children hospital and to describe risk group and decrease length of stay in hospital.
- Trial name
- NCT03484572
- Testing
- Anthropometric measures
- Volunteers
- 300 people
- Sponsor
- Assiut University
Esophageal Cancer, Nimotuzumab
Nimotuzumab Concurrent With Chemoradiotherapy for Esophageal Cancer Patients
Elderly or malnourished patients diagnosed with locally advanced esophageal squamous cell carcinoma (ESCC) had poor prognosis. Radiotherpy was an important and effective treatment in treating ESCC.
- Conditions
- Esophageal Cancer, Nimotuzumab, Chemoradiotherapy, Chemotherapy
- Trial name
- NCT06429839
- Testing
- Nimotuzumab with chemoradiotherapy
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Bariatric Surgery Candidate, Malnutrition
BagEL - Bariatric Patients in Primary Care: Post-operative Nutrition and Lifestyle Management
There is a growing number of patients undergoing bariatric surgery requiring lifelong follow-up. BagEL (Bariatric Patients in Primary Care: Post-operative Nutrition and Lifestyle Management) is a survey to evaluate a newly…
- Trial name
- NCT03792412
- Testing
- Usability Questionnaire
- Where
- Austria
- Volunteers
- 220 people
- Sponsor
- Medical University of Vienna
Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water.
- Trial name
- DrinkAge (NCT07892742)
- Testing
- Water
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Polytechnic University of Santarém
Tibial Fracture
Vitamin D Supplement for Patients With Tibial Fracture
The purpose is to study: 1. the frequency of vitamin D deficiency at patients with tibial fracture treated with an external ring fixator 2. if vitamin D supplement facilitates fracture healing 3.
- Trial name
- NCT01955577
- Testing
- Vitamin D3 cholecalciferol
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Northern Orthopaedic Division, Denmark