Clinical trials: Malnutrition, Child
X-linked Hypophosphatemia (XLH)
Effective Dosing of Burosumab in XLH
X-linked hypophosphataemia (XLH) is a rare, hereditary condition. The genetic defect leads to low blood phosphate levels and vitamin D suppression. Phosphate is required for strong bones and teeth and to store energy in cells.
- Trial name
- NCT07183579
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Nutrition Disorder, Child, Neurologic Disorder
Whey-Based Partially Hydrolyzed Formula Versus Polymeric Formula On Undernourished Neurologically Impaired Children: Open-labelled Randomized Study
Purpose: Undernutrition is common in neurologically impaired children. It increases the burden of comorbidities and affects the quality of life of these children.
- Trial name
- NCT06356103
- Testing
- Whey-Based Partially Hydrolyzed Formula, received 50% of their caloric requirements as isocaloric polymeric formula (standard ) and 50% standard nutritional feeding according to ESPGHAN guidelines
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Low Birthweight, Preterm Birth
Enhancing Nutrition and Antenatal Infection Treatment for Maternal and Child Health in Ethiopia
The ENAT study will test the impact of packages of antenatal interventions to enhance maternal nutrition and manage pregnancy infections on the outcomes of infant birth size, gestational length, and infant growth in the first 6…
- Conditions
- Low Birthweight, Preterm Birth, Maternal; Malnutrition, Affecting Fetus, Sexually Transmitted Diseases
- Trial name
- ENAT (NCT04171388)
- Testing
- Azithromycin 500 mg, Multiple Micronutrient or Fortified Balanced Energy Protein Supplement, Enhanced Infection Management Package (EIMP)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Wasting, Undernutrition
Improvement of Nutrition Status, Digestive Conditions, and Upper Respiratory Infections by Using Oral Nutritional Supplementation on Children in Vietnam
Evaluating the efficiency of using the nutrient production toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, anorexia, and upper respiratory infections in children aged 24 - 71 months.
- Conditions
- Wasting, Undernutrition, Malnourished, Malnutrition
- Trial name
- NCT05570045
- Testing
- Colos Gain
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Malnutrition
L-Carnitine Supplementation, Rate of Weight Gain and EED in Children With SAM
Background: Burden: Globally, an estimated 14.3 million under-5 children are severely malnourished. Two-thirds of them live in Asian countries, including Bangladesh.
- Trial name
- NCT05083637
- Testing
- L- carnitine oral solution
- Where
- Bangladesh
- Volunteers
- 98 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Overweight, Physical Activity
The Healthy Elementary School of the Future
Unhealthy lifestyles in early childhood are a major global health challenge. These lifestyles often persist from generation to generation and contribute to a vicious cycle of health-related and social problems.
- Conditions
- Overweight, Physical Activity, Malnutrition, Child Development
- Trial name
- THESF (NCT02800616)
- Testing
- The Healthy Primary School of the Future, The Physical Activity School
- Volunteers
- 2,349 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Autism, Vitamin D Deficiency
Open Label Clinical Trial of Vitamin D in Children With Autism
Primary: to investigate tolerability of interventional high dose Vitamin D3 supplementation, titrated to reach serum levels near the high end of the reference range (30-100 ng/ml), in vitamin D deficient pediatric Autism Spectrum…
- Trial name
- NCT01535508
- Testing
- Liquid Vitamin D
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Malnutrition, Child
Effectiveness of a Positive Deviance Program in Reducing Childhood Undernutrition
Globally, childhood malnutrition remains a public health concern. Malnutrition can be diverse from undernutrition to overnutrition.
- Trial name
- NCT04688515
- Testing
- Nutrition program developed using positive deviance approach
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Malnutrition, Child
Integrated Livestock Management for Nutrition in Children Under Five Years of Age in Chad
The main objective of this study is to determine the effectiveness of a livestock management intervention, with considerations for animal food security, water contamination from animals, and nutrition counseling, in reducing the…
- Trial name
- NCT05890378
- Testing
- Testing water
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Tufts University
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Anemia; Deficiency, Nutritional, With Poor Iron Absorption
Fe Absorption in Mother and Child Pairs From Wheat Fortified With Iron With and Without Phenolic Containing Beverages
In Senegal, iron deficiency affects 39% of and 82% of women and children between 12 and 50 months indicating that iron deficiency is a major health problem.
- Trial name
- Fe_Senegal (NCT02437955)
- Testing
- Ferrous sulfate fortified bread with tea, ferrous sulfate fortified bread with water, Ferrous fumarate fortified bread with tea
- Where
- Senegal
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia
Effect of Soaking Complementary Foods Flour on Hemoglobin Concentration, Anthropometric Deficits and Episode of Diarrheal, Cough and Fever Morbidities
Removing anti nutrient factors using simple cost-effective and sustainable household methods to improve nutritional status of children in communities were plant based complementary foods are the main source of Nutrients is highly…
- Trial name
- NCT05254717
- Testing
- counselling
- Where
- Ethiopia
- Volunteers
- 700 people
- Sponsor
- Madda walabu university
Moderate Acute Malnutrition
Modified Dosage for Moderate Acute Malnutrition (MODAM-MAM)
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited…
- Trial name
- MODAM-MAM (NCT06056089)
- Testing
- ready-to-use supplementary food (RUSF), ready-to-use therapeutic food (RUTF)
- Where
- 3 sites in Ethiopia
- Volunteers
- 2,400 people
- Sponsor
- Action Against Hunger USA
Vitamin D Deficiency
Prevalence of Early Childhood Caries in Egyptian Children With Serum Vitamin D Deficiency.
To detect the effect of vitamin D deficiency in the development of early childhood caries (ECC) among Egyptian children.
- Trial name
- NCT03158155
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Nancy Ahmed El Salmawy
Malnutrition in Children
Impact of School Meal Program on Child Nutrition and Academic Performance
This study will assess the impact of a school meal program on the nutritional status and academic performance of primary school children in Lahore, Pakistan.
- Trial name
- NCT07800208
- Testing
- School Meal Program
- Where
- Pakistan
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Malnutrition, Diarrhea
WASH Benefits Bangladesh
Brief Summary: The purpose of this study is to measure the independent and combined effects of interventions that improve water quality, sanitation, hand washing, and nutrition on child growth and development in the first years…
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- NCT01590095
- Testing
- Water quality, Sanitation, Hand washing
- Where
- Bangladesh
- Volunteers
- 5,040 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Health Behavior, Nutrition Poor
Hands On Nutrition Education to Improve Childhood Health
The main goals of this study is to better understand how an experiential cooking, movement and mindfulness intervention influence elementary school children at Spring Valley School.
- Trial name
- NCT04109768
- Testing
- nutrition and activity
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tuberculosis, Child Health
The DECIDE-TB Trial; Validation of Treatment Decision Algorithms for Childhood Tuberculosis
The Decide-TB project aims to generate evidence for the implementation of a comprehensive Treatment Decision Algorithms (TDA) based approach for TB in children living in high TB burden and resource-limited countries, at District…
- Conditions
- Tuberculosis, Child Health, HIV, Severe Acute Malnutrition
- Trial name
- DTB (NCT06593080)
- Testing
- The comprehensive TDA based approach
- Where
- 29 sites in Zambia
- Volunteers
- 30,240 people, healthy volunteers welcome
- Sponsor
- Chishala Chabala
Malnutrition Severe
PSYCHOSOCIAL STIMULATIONS AND TREATMENT OUTCOME OF SEVERE ACUTE MALNOURISHED CHILDREN
A playroom and a playground are already part of the stabilization unit and are furnished with basic facilities for engaging the SAM children in play-based motor, language, and personal-social activities.
- Trial name
- NCT06653790
- Testing
- Psychosocial stimulations
- Volunteers
- 800 people
- Sponsor
- Universiti Putra Malaysia
Type 1 Diabetes Mellitus, Vitamin D Deficiency
Vitamin D Supplementation and Glycemic Control Improvement Among Type 1 Diabetic Children
Type 1 diabetes mellitus (T1DM) is an immune-mediated disease characterized by diminished insulin secretion due to damage to islets of Langerhans in the pancreas, which eventually results in high levels of glucose in the blood.
- Trial name
- NCT05141968
- Testing
- vitamin D supplements (2000 IU/day)
- Where
- Palestinian Territories
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University