Clinical trials: Malnutrition, Child
Kwashiorkor, Marasmus
Safety and Metabolic Study of Highly Active Antiretroviral Therapy (HAART) in Malnourished Children With HIV
It is unclear whether children with HIV and severe acute malnutrition can be started on highly active antiretroviral therapy (HAART) safely while they are still malnourished and the manner in which this therapy should start.
- Conditions
- Kwashiorkor, Marasmus, Severe Acute Malnutrition, HIV
- Trial name
- ARMAM (NCT01529125)
- Testing
- zidovudine, lamivudine, nevirapine
- Where
- Malawi
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Malnutrition
Malnutrition and Outcome in Hospitalized Children in Europe
Malnutrition in children has even more severe consequences on disease course and long-term health than malnutrition in adults. According to prior studies, malnutrition affects about 15-30 % of hospitalized children in Europe…
- Trial name
- NCT01132742
- Where
- 14 sites in Croatia, Denmark and 9 more
- Volunteers
- 2,567 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Child Nutrition Disorders
Nutritional Intervention For The Treatment Of Uncomplicated SAM
nutritional intervention with ready to use therapeutic food (plumpy nut. by Unicef) and Prebiotics supplimentation ( Galactooligosaccarides).
- Trial name
- SAM (NCT05390437)
- Testing
- Nutritional intervention with Ready to use theraputic food (RUTF) and prebiotic GOS (galacto oligosaccharides) in combination
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Sanaullah Iqbal
Nutritional Rickets, Bone Turnover Rate Disorder
Effectiveness of Vitamin C Supplementation in Treatment of Rickets
Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C…
- Trial name
- NCT05310760
- Testing
- Vit C
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Severe Acute Malnutrition, Moderate Acute Malnutrition (MAM)
Regular Growth Monitoring (RGM) of Young Children in Guinea-Bissau
Wasting (severe thinness) is a common and serious problem among young children in rural Guinea-Bissau. Community Health Agents (CHAs) can help prevent malnutrition by regularly measuring children's growth and advising families on…
- Trial name
- NCT07584395
- Testing
- Regular Growth Monitoring (RGM) by Community Health Agents
- Where
- Guinea-Bissau
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Severe Acute Malnutrition, Persistent Diarrhea
Trial of Rice-Based F-75 in Severe Malnutrition & Persistent Diarrhea in Children (SAM-RICE Study)
The goal of this study is to find out if a rice-based version of the F-75 therapeutic food helps children with severe acute malnutrition (SAM) and persistent diarrhea recover better than the standard commercial F-75.
- Conditions
- Severe Acute Malnutrition, Persistent Diarrhea, Children
- Trial name
- SAM-RICE (NCT07070856)
- Testing
- WHO-recommended standard therapeutic milk used for stabilization phase in SAM), HO-recommended Rice based therapeutic milk used for stabilization phase in SAM)
- Where
- 2 sites in Pakistan
- Volunteers
- 320 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Vitamin D Deficiency, 25-Hydroxyvitamin D3 Deficiency, Selective
Effect of Vitamin D3 Supplementation in Children From 12 to 30 Months of Age.
Background Vitamin D (VD) is essential for calcium absorption, bone health and growth in children. In a national representative sample authors found mean serum concentration of 25-Hydroxi-Vitamin-D (25-OH-D) of 59 nmol/L, in…
- Trial name
- NCT03544671
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Diarrhea, Malnutrition, Other Nutritional Deficiencies
HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition
This study will determine the effect of 7 days supplementation of alanyl-glutatime or glycine on the damaged intestinal barrier function on day 8 in children with persistent diarrhea or malnutrition.
- Trial name
- NCT00133562
- Testing
- Alanyl-glutamine, Glycine
- Volunteers
- 108 people
- Sponsor
- University of Virginia
Overweight and Obesity, Malnutrition, Child
Effect of an Educational Intervention About Front of Package Labeling in Children and Caregivers.
The goal of this clinical trial is to evaluate the effect of a digital educational intervention of front-of-package warning labeling on the selection and purchase of food in elementary school children and their caregivers.
- Trial name
- NCT06102473
- Testing
- Nutritional education
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Diana Avila Montiel
Vitamin D Deficiency, Iodine Deficiency
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.
Vitamin D deficiency is common worldwide, including in infants and children, and rickets remains a public health concern in many developing countries.
- Conditions
- Vitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
- Trial name
- Haiti (NCT02301520)
- Where
- 2 sites in Haiti
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Malnutrition
Acceptability of LNS for Infants and Young Children in Guatemala
This study aims to assess the acceptability of lipid-based nutrient supplements (LNS) for use as nutritional supplements for infants and young children in Guatemala. The study was conducted in three phases.
- Trial name
- NCT01148641
- Testing
- LNS
- Where
- Guatemala
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Malnutrition, Pneumonia
Childhood Acute Illness and Nutrition Network
The CHAIN Network aims to identify modifiable biomedical and social factors driving the greatly increased risk of mortality among young undernourished children admitted to hospital with acute illness, as inpatients and after…
- Conditions
- Malnutrition, Pneumonia, Diarrhea, Sepsis
- Trial name
- CHAIN (NCT03208725)
- Where
- 8 sites in Bangladesh, Kenya and 3 more
- Volunteers
- 4,335 people
- Sponsor
- University of Oxford
Hypovitaminosis D
Vitamin D Versus Placebo in the Treatment of Vague Musculoskeletal Pain in Children
Other studies suggest that low Vitamin D levels may contribute to musculoskeletal pain. Hypothesis: Administration of oral Vitamin D supplements will improve vague musculoskeletal pain in children.
- Trial name
- NCT00944606
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Wasting, Moderate Acute Malnutrition
Effectiveness of Nutritional Products to Treat Moderate Acute Malnutrition
The purpose of this study is to determine whether an improved corn-soya blend (CSB+) and a new formulated ready-to-use supplementary food (RUSF) are effective in the treatment of moderate acute malnutrition in children.
- Trial name
- NCT01898871
- Testing
- A daily ration of 40 kcal/kg of body weight during 56 days
- Where
- 2 sites in Cameroon
- Volunteers
- 81 people
- Sponsor
- Centre for Food and Nutrition Research, Yaounde
Refeeding Syndrome
Prevention of Refeeding Syndrome
To determine effects of different caloric density intake in prevention of refeeding syndrome in critically ill children
- Trial name
- NCT06589479
- Volunteers
- 50 people
- Sponsor
- Assiut University
Neuroblastoma
Nutritional Status in Neuroblastoma in Sao Paolo, Brazil
This study proposes to investigate the effect of treatment of neuroblastoma on nutritional status, assessed by body mass index (BMI) z score, and body composition evaluated by mid-upper arm circumference (MUAC), from diagnosis…
- Trial name
- NCT03517280
- Where
- Brazil
- Volunteers
- 17 people
- Sponsor
- Columbia University
Hypophosphatasia (HPP)
Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)
This clinical trial studied the safety and efficacy of asfotase alfa in children with HPP compared to a historical control group.
- Trial name
- NCT00952484
- Testing
- asfotase alfa
- Where
- 2 sites in United States, Canada
- Volunteers
- 13 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Vitamin A Deficiency, Pediatric
Efficacy and Safety of Vitamin A Treatment for Children With Sepsis
The prevalence of vitamin A deficiency was found high in children with sepsis. Whether those patients will benefit from the vitamin A supplementation is unknown.
- Conditions
- Vitamin A Deficiency, Pediatric, Sepsis
- Trial name
- NCT04127968
- Testing
- Vitamin A, Oil
- Volunteers
- 450 people
- Sponsor
- West China Hospital
Stunting, Wasting
Impact Evaluation of Benazir Nashonuma Program (BNP) on Stunting Among Under-five Children
The aim of the study is to evaluate the impact of Benazir Nashonuma Program (BNP) on prevalence of stunting among under-five children in low income setting of Pakistan.
- Conditions
- Stunting, Wasting, Anemia, Nutrient Deficiency
- Trial name
- NCT06025786
- Testing
- Benazir Nashonuma Program (BNP)
- Where
- Pakistan
- Volunteers
- 13,200 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Child Nutrition Disorders
The Pediatric HIV Nutrition Study in Uganda
This will be cohort study design with both qualitative and quantitative methods of data collection. The investigators are aiming to study 64 HIV positive children as healthy controls either initiating ART or already on ART and 86…
- Trial name
- NOURISH (NCT02421302)
- Testing
- RUTF
- Where
- 2 sites in Uganda
- Volunteers
- 150 people
- Sponsor
- Infectious Diseases Institute