Clinical trials: Malnutrition, Child
Malnutrition, Child, Severe Acute Malnutrition
Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition
Amoxicillin is recommended by the World Health Organization (WHO) as adjunctive therapy for the treatment of uncomplicated severe acute malnutrition (SAM).
- Trial name
- AMOUR (NCT06010719)
- Testing
- Azithromycin, Amoxicillin
- Where
- Burkina Faso
- Volunteers
- 3,000 people
- Sponsor
- University of California, San Francisco
Vitamin A Deficiency
The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool Children
The study comprises an open-label randomized controlled trial investigating the efficacy of consuming a daily ration of pro-vitamin A biofortified cassava on vitamin A status of Nigerian children, aged 3-4 years old (n=200).
- Trial name
- CASSAVITA II (NCT02627222)
- Testing
- Pro-vitamin A biofortified cassava, White cassava
- Where
- Nigeria
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Wageningen University
HIV Infections, Immune Activation
The University of Zimbabwe College of Health Science (UZ-CHS) BIRTH COHORT Study
Background Commencement of lifelong highly active antiretroviral therapy (HAART) immediately after HIV diagnosis (option B+), for treatment of human immunodeficiency virus (HIV), has greatly improved maternal-infant health in sub…
- Conditions
- HIV Infections, Immune Activation, Comorbidities
- Trial name
- UZ-CHS-BC (NCT04087239)
- Testing
- HIV
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Severe Acute Malnutrition
Efficacy of Striatin in Malnourished Children
This is a double-blind randomized-controlled clinical trial to identify the effect of Striatin (snakehead fish extract) supplementation in increasing body weight, improving acute inflammatory markers and microbiota profiles in…
- Trial name
- NCT07089329
- Testing
- Striatin
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Sriwijaya
Obesity, Childhood, Vitamin D Deficiency
The Changes of Body Composition, Glucolipid Metabolism and Bone Metabolism in Obese Children After Weight Loss
Vitamin D plays a significant role in calcium and phosphorus homeostasis for maintaining structural integrity and function of musculoskeletal system.
- Trial name
- NCT03490448
- Testing
- aerobic exercise and appropriate caloric control
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Diet; Deficiency
Cross-sectional Dietary Intake Survey on Ivorian School-Aged Children and Women of Reproductive Age
A cross-sectional dietary intake study was conducted with 423 Ivorian school aged children (SAC, 6-12 years) and 423 women of reproductive age (WRA, 15-49 years) from four cities, recruited by two-stage random sampling.
- Trial name
- AN (NCT06175130)
- Where
- Netherlands
- Volunteers
- 846 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Congenital Heart Disease
Effect of Feeding With Nutrient Dense Formula in Malnourished Infants and Children With Congenital Heart Defects
Infants with congenital heart disease (CHD) are usually born with a normal weight but develop malnutrition over time, and about 20-50% of these children are usually malnourished. Malnutrition in these patients is multifactorial.
- Trial name
- NCT04795076
- Testing
- Infant formula
- Where
- Iran
- Volunteers
- 65 people
- Sponsor
- Shahid Beheshti University
Down Syndrome, Vitamin D Deficiency
Effect of Exercise Intensity on Vitamin D
Children with Down's syndrome (DS) are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication due to increased intestinal absorption or decreased vitamin D…
- Trial name
- NCT05024110
- Testing
- High intensity treamill exercise training., Moderate intensity treamill exercise training.
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- Taif University
Child Malnutrition
Post Discharge Trial to Enhance Immunity in Severely Malnourished Children
The goal of this study is to evaluate the efficacy of microbiota-directed food in comparison to zinc with micronutrient powder and Khichuri on changes in circulating immune cells (monocytes, T cells, B cells, and NK cells) in…
- Trial name
- NCT06530485
- Testing
- Microbiota-directed food, Khichuri
- Where
- Bangladesh
- Volunteers
- 154 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Child Malnutrition
Effects of Prebiotics on Metagenomic Diversity and Abundance in Young Children With Acute Malnutrition
Malnutrition is a major global public health issue, contributing to poor health and early morbidities in children under five, particularly in developing countries.
- Trial name
- P-MAM (NCT06155474)
- Testing
- Prebiotic galacto-oligosaccharide (GOS) Powder, Starch Only, RUTF + Starch
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Sickle Cell Disease, Vitamin D Deficiency
High Dose Vitamin D Supplementation in Children With Sickle Cell Disease
Suboptimal vitamin D status is well reported in sickle cell disease (SCD) patients and associated with a negative impact on health-related quality of life (HRQL).
- Conditions
- Sickle Cell Disease, Vitamin D Deficiency, Health Related Quality of Life, Hand Grip Strength
- Trial name
- NCT06274203
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Malnutrition
Comparing Performance of Simplified Mid-Upper Arm Circumference Devices ("Click-MUACs") to Detect Acute Malnutrition
The Click-Mid-Upper Arm Circumference study aims to describe and compare the performance of a set of three simplified mid-upper arm circumference classification devices ("Click-MUAC") for use by mothers and caregivers to screen…
- Trial name
- NCT02833740
- Testing
- Click-MUAC prototype & regular MUAC tape
- Where
- Kenya
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Action Contre la Faim
Malnutrition, Child
Comparison of Different Feeding Protocols for the Treatment of Acute Malnutrition
Though malnutrition is prevalent worldwide but its situation is alarming in low- and middle-income countries. Pakistan has also been facing an alarming situation of prevailing severe malnutrition.
- Trial name
- NCT04045249
- Testing
- Home based food
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Integrated Reproductive Maternal Newborn & Child Health and Nutrition Program, Punjab
Overweight, Obesity, Small for Gestational Age, Prematurity
Novel Screening Tools For the Evaluation and Management of Malnourished Children in the Developing World
The purpose of this study is to evaluate the accuracy of a new device that may be used for the evaluation and management of malnourished infants and children.
- Trial name
- NCT02449408
- Testing
- Measurement of leptin and adiponectin obtained through blood sampling via venipuncture or finger/heelstick using novel screening tool
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Duke University
Children, Malnutrition
Effects of "For-Baby" Supplementation on Young Children's Physical Growth and Diarrhea Episodes
The LaoBiome Study is a community-based, randomized, placebo-controlled trial with two study arms conducted in Lao People's Democratic Republic.
- Trial name
- LaoBiome (NCT05185973)
- Testing
- "For Baby "supplements provided as powder, Micronutrient powder provided as powder
- Volunteers
- 1,200 people
- Sponsor
- Lao Tropical and Public Health Institute
Malnutrition
Validation of the STAMP Screening Tool For Pediatric Nutritional Risk
Background: Insufficient nutritional intake, with or without concomitant morbidity, leads to weight loss or insufficient weight gain, is related to an increase in morbidity and mortality and exposes the child to medical…
- Trial name
- STAMP2 (NCT01718769)
- Testing
- questionnaire STAMP
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Child Malnutrition
The Impact of Community Health Workers on Child Malnutrition in the Philippines
This study will focus on a new community health worker (CHW) program called 'Flourish', which is implemented by Philippine non-governmental organization (NGO) International Care Ministries (ICM).
- Trial name
- NCT05774314
- Testing
- Community Health Worker Intervention
- Where
- 4 sites in Philippines
- Volunteers
- 7,650 people, healthy volunteers welcome
- Sponsor
- International Care Ministries, Philippines
Malnutrition
Comparison of a Two Ready-to-use Supplementary Foods of Differing Protein Quality for the Treatment of MAM.
This is a prospective, randomised, double-blinded, controlled clinical effectiveness trial of two supplementary foods in the treatment of MAM. The setting will be 21 rural sites in southern Malawi.
- Trial name
- NCT03549156
- Testing
- C-RUSF, HIPRO RUSF
- Where
- Malawi
- Volunteers
- 1,858 people
- Sponsor
- Washington University School of Medicine
Severe Acute Malnutrition
Follow Up of Severely Malnourished Children (FUSAM)
The overall objective of the research is to assess the long-term and cost-effectiveness of a combined nutrition psychosocial intervention to a stand-alone nutritional treatment of children with Severe Acute Malnutrition (SAM)…
- Trial name
- FUSAM (NCT02672982)
- Testing
- NUTPSY treatment, NUT treatment
- Where
- Nepal
- Volunteers
- 427 people
- Sponsor
- Action Contre la Faim
Malnutrition, Malnutrition, Child
Double Duty Interventions and Its Impact on Double Burden of Malnutrition in Children Under Five Years
Background: Double burden of malnutrition is an emerging public health problem among children under-five years due to the inevitable consequences of nutritional transition.
- Conditions
- Malnutrition, Malnutrition, Child, Obesity, Undernutrition
- Trial name
- DBM (NCT05791305)
- Testing
- double duty intervention packages
- Where
- 2 sites in Ethiopia
- Volunteers
- 456 people
- Sponsor
- Debre Berhan University