Clinical trials: Malnutrition
Mitochondrial Diseases, Mitochondrial Myopathies
Nutritional Assessment in Mitochondrial Cytopathy
The aim of this study is to assess nutritional intake (quantitatively and qualitatively), nutritional state and body composition of patients suffering from mitochondrial cytopathy, compared to healthy controls.
- Conditions
- Mitochondrial Diseases, Mitochondrial Myopathies, Mitochondrial Cytopathies
- Trial name
- NAMITO (NCT02375438)
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypercholesterolemia, Cognitive Dysfunction
The Dual Impact of Homocysteine and Cholesterol on Cognitive Functions
The study evaluates if the relationship between total serum cholesterol is dependent on the total serum homocysteine. Fasting blood samples will taken from participants and two batteries of cognitive scales will be used to asses…
- Conditions
- Hypercholesterolemia, Cognitive Dysfunction, Hyperhomocysteinemia
- Trial name
- NCT03631238
- Testing
- Blood sampling for total cholesterol and homocysteine and cognitive assessment by psychometric tests.
- Where
- Egypt
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Assiut University
Malnutrition
Validation of the STAMP Screening Tool For Pediatric Nutritional Risk
Background: Insufficient nutritional intake, with or without concomitant morbidity, leads to weight loss or insufficient weight gain, is related to an increase in morbidity and mortality and exposes the child to medical…
- Trial name
- STAMP2 (NCT01718769)
- Testing
- questionnaire STAMP
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Vitamin D Deficiency, Malnutrition
Optimizing Treatment Programs for Chronic Kidney Disease-mineral and Bone Disorder and Malnutrition
Multi-center, prospective, randomized, controlled study to verify the clinical effectiveness of K / DOQI guidelines. The efficiency and safety of Vitamin D2 and low protein diet treatment for prevention and treatment of CKD-MBD…
- Trial name
- NCT02005302
- Testing
- 1,25(OH)2 Vitamin D3, Vitamin D2, low protein diet
- Where
- 5 sites in China
- Volunteers
- 600 people
- Sponsor
- Wenhu Liu
Sarcopenia, Cirrhosis, Liver
LIver FRAilty Management IN Cirrhosis (LIFRAMIN)
The goal of this clinical trial is to compare food for special medical purposes (Aminolife Plus, by Piemme Pharmatech) vs. placebo in improving muscle mass and function in a cohort of cirrhotic patients.
- Conditions
- Sarcopenia, Cirrhosis, Liver, Malnutrition; Protein
- Trial name
- LIFRAMIN (NCT06573229)
- Testing
- Aminolife Plus by Piemme Pharmatech, Italy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
End Stage Renal Disease
Effects of Nutritional Supplementation on Protein and Energy Homeostasis in Malnourished Chronic Hemodialysis Patients
The goal of this study is to evaluate the metabolic effects of concomitant use of three consecutive doses of recombinant human growth hormone over three days and exercise during continuous nutrient infusion in chronic…
- Trial name
- NCT00244075
- Testing
- nutritional supplement, recombinant human growth hormone (rcGH), exercise
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Vanderbilt University
Weight Loss
The Undernourished Patient: Prevention and Treatment
The purpose of this study is to determine whether a nutrition intervention during a rehabilitation stay followed by nutritional advice after discharge, can improve the nutritional status of the patients after 3 months.
- Trial name
- NCT01632072
- Testing
- Nutritional support
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Oslo
Congenital Heart Disease, Thiamine Deficiency
The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease
Currently, research on the effect of thiamine administration during transcatheter closure on the structure and function of the left ventricle by examining levels of matrix metalloproteinase-9 and tissue inhibitor of…
- Conditions
- Congenital Heart Disease, Thiamine Deficiency, Patent Ductus Arteriosus, Ventricular Septal Defect
- Trial name
- NCT06298344
- Testing
- Thiamine
- Where
- Indonesia
- Volunteers
- 86 people
- Sponsor
- Universitas Sumatera Utara
Endothelial Dysfunction, Hyperhomocysteinemia
Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function
The effect of a combination product (Verum ) with L-arginine, Pycnogenol, vitamin K2, R-(+)-alpha-lipoic acid and vitamins B6, B12 and folic acid is investigated in a double blind placebo-controlled cross-over study.
- Conditions
- Endothelial Dysfunction, Hyperhomocysteinemia, Hypertension Grade I, Subgroup "Borderline" (WHO)
- Trial name
- NCT02392767
- Testing
- Verum
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dr. Loges & Co. GmbH
COVID
Functional and Respiratory Rehabilitation and Nutritional Care of COVID-19 Patients (RECOVER-19)
Following the acute phase of COVID, some patients may have sequelae, such as breathing difficulties or malnutrition. We hypothesize that a functional and respiratory rehabilitation program associated with personalized nutritional…
- Trial name
- RECOVER-19 (NCT04466800)
- Testing
- Intervention group_rehabilitation program
- Where
- 5 sites in France
- Volunteers
- 160 people
- Sponsor
- Rennes University Hospital
Sarcopenia, Frailty
Sarcopenia Prevention With a Targeted Exercise and Protein Supplementation Program
Physical inactivity and protein malnutrition have been implicated to be key and modifiable causes of enhanced muscle mass loss among seniors.
- Conditions
- Sarcopenia, Frailty, Malnutrition; Protein, Fall
- Trial name
- STRONG (NCT03417531)
- Testing
- Protein Supplement, Protein-free Supplement, Active Exercise
- Where
- 2 sites in Switzerland
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Vitamin A Deficiency
Efficacy of Newborn Vitamin A Supplementation in Improving Immune Function
Vitamin A supplementation at birth may increase survival of infants through one year of age by reducing mortality from infectious diseases, though current studies are not conclusive on this point.
- Trial name
- NCT01583972
- Testing
- retinyl palmitate
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Risk of Malnutrition
Nutritional Education for Dependant Patients
Objective: To assess the effect of a nutritional educational intervention on the risk of malnutrition dependent patients aimed at the caregivers.
- Trial name
- atdom_nut (NCT01360775)
- Testing
- nutritional counseling
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Frailty, Malnutrition
Frail2Fit Study: Online Nutrition and Exercise Support for Older Adults With Frailty
Frail2Fit will explore the feasibility of training volunteers to deliver online nutrition, exercise, and behaviour change (supported self-management) to improve the health of older people after discharge from hospital.
- Conditions
- Frailty, Malnutrition, Sedentary Behavior
- Trial name
- NCT05384730
- Testing
- Group nutrition and exercise support
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Cirrhosis, Hepatic Encephalopathy
Bioelectrical Impedance Vector Analysis in Cirrhotic Patients
Protein-energy malnutrition and muscle wasting are a common finding among patients with liver cirrhosis. Its prevalence may range from 50-90% depending on the methods used for nutritional assessment.
- Trial name
- BIVA (NCT01603953)
- Where
- Mexico
- Volunteers
- 250 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Osteogenesis Imperfecta, Rare Bone Disorders
Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis
MOSAIC aims to determine whether oro-dental morphological anomalies, particularly palatal morphology, associated with rare bone and cartilage diseases can be precisely characterized using 3D digital models analysed through…
- Conditions
- Osteogenesis Imperfecta, Rare Bone Disorders, Hypophosphatemia, X-Linked
- Trial name
- MOSAIC (NCT07666269)
- Testing
- intra-oral 3D optical impression
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Anorexia of Aging, Malnutrition or Risk of Malnutrition
The SAVOR Study: Appetite and Physiological Responses
The study aims to identify key physiological factors that differentiate older adults with healthy appetites from those experiencing appetite decline.
- Trial name
- SAVOR (NCT07636369)
- Testing
- Shredded Chicken Congee
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Malnutrition, Cancer
Enteral Nutrition in Cancer Patients
CONTEXT AND OBJECTIVE: Tumor and its therapy have adverse effects on the nutritional status of cancer patients, leading to nutritional support.
- Trial name
- NCT01304446
- Testing
- industrialized oral supplementation (IOS) and tube feeding regimen (TFR) with Nutren
- Sponsor
- Grupo de Apoio ao Adolescente e a Crianca com Cancer
Cirrhosis, Chronic Liver Disease
Copper Supplementation in Cirrhosis
End stage liver disease or cirrhosis is a major cause of mortality in the United States and the world. Other than targeting the underlying cause, such as alcohol cessation and antiviral therapy, very few medical treatments can…
- Conditions
- Cirrhosis, Chronic Liver Disease, Fibrosis, Infection
- Trial name
- NCT07471542
- Testing
- Copper Gluconate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Undernutrition, Stunting
The Effectiveness of HBM-based Education Program on Improve Knowledge and Behaviors
The randomized controlled trial design with one intervention arm (nutrition education and complementary feeding) and one control (usual care) arm (1:1 ratio).
- Conditions
- Undernutrition, Stunting, Wasting, Underweight
- Trial name
- NCT05517395
- Testing
- health nutrition education, usual care
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
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