Clinical trials: Malnutrition
X-linked Hypophosphatemic Rickets/Osteomalacia
A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia
Before switching to the post-marketing study: To evaluate the efficacy and safety of KRN23 administered subcutaneously once every 2 weeks in children with X-linked hypophosphatemic rickets/osteomalacia(XLH).
- Trial name
- NCT03233126
- Testing
- KRN23
- Where
- 4 sites in Japan
- Volunteers
- 16 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Thrombosis
Analysis of the Impact of the Undernutrition on the Cerebral Infarct in Thrombolized Patients
Many clinical trials show that 30 to 50 % of the hospitalized patients are undernourished in various degrees. This prevalence didn't change since 15-20 years The fact is that the present undernutrition in the admission…
- Trial name
- NCT03303820
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hypocalcemia, Vitamin D Deficiency
The Impact of Vitamin D Deficiency on Hypocalcaemia Following Total Thyroidectomy
Post-operative hypocalcaemia following total thyroidectomy is a well-known complication and becoming a major area of research. Many factors are assumed to increase the incidence of post-thyroidectomy hypocalcaemia, but the impact…
- Trial name
- NCT03063060
- Testing
- vitamin D levels and Calcium levels examination
- Volunteers
- 60 people
- Sponsor
- Hillel Yaffe Medical Center
Mortality, Hyperhomocysteinemia
5-methyltetrahydrofolate Survival and Inflammation in ESRD Patients
A randomized prospective study was done to determine whether i.v. 5-methyltetrahydrofolate vs oral folate improved survival in ESRD patients. Homocysteine, CRP, Lp(a), albumin, folates, vitamin B6 and B12 were checked.
- Conditions
- Mortality, Hyperhomocysteinemia, Inflammation
- Trial name
- NCT00626223
- Testing
- 5-MTHF (5-methyltetrahydrofolate), folic acid
- Where
- Italy
- Volunteers
- 341 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Functional Constipation in Children
Is Vitamin D Deficiency Linked to Functional Constipation In Children
Constipation is one of the most common causes of patient visits to pediatric clinics. Prevalence of constipation is estimated between 1.9-27.2% in the USA (Rasquin et al., 2006).
- Trial name
- NCT06657313
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
COPD
High Protein Diet and Physical Activity in COPD
COPD outpatients with severe and very severe (grade III-IV) disease at risk of malnutrition commencing rehabilitation (7-10-week physical activity program) were randomized to receive a high protein diet (≥ 25 energy percentage)…
- Trial name
- NCT04888182
- Testing
- intervention
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Jens Rikardt Andersen
Complications of Bariatric Procedures, Avitaminosis
Vitamin Supplementation After Bariatric Surgery
The objectives in this study are to provide information on the efficacy of transdermal supplement patches on treating nutrient malabsorption and deficiency in post-op bariatric patients, and to determine short-term body…
- Trial name
- NCT02686905
- Testing
- Chewable Multivitamin with Iron, PatchMD Vitamin D3/Calcium Patch, PatchMD Multivitamin Patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- California State Polytechnic University, Pomona
Malnourished, Stomach Neoplasms
The Effects of Preoperative and Postoperative Oral Nutritional Supplements in Malnourished Post-gastrectomy Patients
The objective of this study is to evaluate the effect of a perioperative nutrition strategy using oral nutritional supplements (ONS) on postoperative complications and improvement in body weight in malnourished patients who…
- Conditions
- Malnourished, Stomach Neoplasms, Gastrointestinal Stromal Tumors
- Trial name
- NCT01421680
- Testing
- Ensure powder
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Seoul National University Hospital
Anemia, Undernutrition
Maternal Nutrition Interventions in Uttar Pradesh, India
Maternal nutrition has been a long-standing concern of health authorities globally and in India. Despite the availability of proven, affordable interventions, and progressive policies and program platforms such as Maternal…
- Conditions
- Anemia, Undernutrition, Underweight, Stunting
- Trial name
- NCT03378141
- Testing
- Maternal Nutrition Behavior change
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Pediatric Migraine, Migraine Disorders, Brain
Comorbidity-Based Propranolol Use in Pediatric Migraine
This observational retrospective cohort study aims to identify clinical and biochemical predictors of response to propranolol prophylaxis in pediatric migraine.
- Conditions
- Pediatric Migraine, Migraine Disorders, Brain, Vitamin D Deficiency
- Trial name
- NCT07103031
- Testing
- Behavioral therapy, Propranolol
- Where
- Turkey (Türkiye)
- Volunteers
- 488 people
- Sponsor
- Kayseri University
Malnutrition, Cerebral Palsy
Nutritional Assessment in Children With Cerebral Palsy
This cross-sectional study aims to assess the current practice of nutritional assessment and management in children with cerebral palsy and to determine the frequency of undernutrition among them.
- Trial name
- NCT07879222
- Volunteers
- 100 people
- Sponsor
- Assiut University
Secondary Hyperparathyroidism
Suspected Deficient Activation of Vitamin D in Patients With Secondary Hyperparathyroidism
The purpose of this study is to determine if a reduction in the enzyme 1-hydroxylase, which activates Vitamin D, is the cause of overactivity of the parathyroid glands (called secondary hyperparathyroidism - normal blood calcium…
- Trial name
- 1hydroxylase (NCT00754442)
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Stroke ( 3 Months After Onset), Dysphagia
Dysphagia Management for Caregivers of Stroke Patients
This randomized controlled experimental study was conducted to evaluate the effects of dysphagia management training provided to caregivers of stroke patients receiving home care.
- Conditions
- Stroke ( 3 Months After Onset), Dysphagia, Palliative Care, Caregiver
- Trial name
- NCT07181629
- Testing
- Control, Dysphagia Management Education
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Uludag University
Cervical Cancers
The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients
The goal of this open-label randomized control trial is to study the effect of immunonutrition in locally advanced cervical cancer (LACC) with standard concurrent chemoradiotherapy.
- Trial name
- NCT06349148
- Testing
- enteral immunonutrition, standard oral enteral nutrition
- Where
- China
- Volunteers
- 50 people
- Sponsor
- SHUANG ZHENG JIA, PhD
Aging
PEU in Elderly TCU Residents
Background: There is tremendous controversy regarding the adequacy/effectiveness of the nutritional care provided in VA Transitional Care Units (TCUs).
- Trial name
- NCT00242684
- Where
- United States
- Volunteers
- 446 people
- Sponsor
- US Department of Veterans Affairs
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Organic Acidemia, Methylmalonic Acidemia
Clinical and Laboratory Study of Methylmalonic Acidemia
Methylmalonic acidemia (MMA), one of the most common inborn errors of organic acid metabolism, is heterogeneous in etiology and clinical manifestations.
- Conditions
- Organic Acidemia, Methylmalonic Acidemia, Inborn Errors of Metabolism
- Trial name
- NCT00078078
- Where
- 3 sites in United States
- Volunteers
- 2,275 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Malnutrition, COPD
Nutritional Status Evaluation of Hospitalized Patients With Acute Respiratory Failure and COPD
Malnutrition is a comorbidity oftenly seen in COPD patients who have progressive chronic inflammation and severity. The investigators aimed to determine the impact of nutritional status and nutrition-related factors on prolonged…
- Trial name
- NCT04639648
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Fatebenefratelli
Vitamin D Deficiency, Polytrauma
Vitamin D and Bone Homeostasis in Ortho Polytrauma Patients
Although vitamin D is known to play a major role in multiple organ functions in healthy adults, including bone homeostasis, its role in the unique population of orthopaedic polytrauma patients has not been well described.
- Conditions
- Vitamin D Deficiency, Polytrauma, Orthopedic Disorder
- Trial name
- NCT03066817
- Testing
- Ergocalciferol 8000 IU/ML Oral Liquid [DRISDOL], Propylene Glycol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York City Health and Hospitals Corporation
Renal Osteodystrophy
Systematic Study of Parameters of Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD)
Bone and mineral disease is a key problem in patients with kidney disease. The available clinical parameters are non-specific, unproven for the assessment of the bone metabolism and do not reflect the complexity and diversity of…
- Trial name
- BoneX (NCT02556216)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Hannover Medical School
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