Clinical trials: Malocclusion of Anterior Teeth, active
Pulp Necrosis, Apical Periodontitis
Comparing Amla (Emblica Officinalis) and 3% Sodium Hypochlorite Against Enterococcus Faecalis in Root Canal Treatment.
Bacteria inside the root canal are a major cause of tooth infections. If they are not completely removed, the infection may continue even after root canal treatment.
- Trial name
- NCT07688005
- Testing
- Sodium Hypochlorite 3% Solution, Emblica officinalis Solution
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Malocclusion of Anterior Teeth
Clinical Evaluation of Zirconium Dioxide Nano-Coated Arch Wires
"This clinical trial aims to evaluate the clinical performance and efficiency of zirconium dioxide nano-coated orthodontic archwires compared to conventional archwires.
- Trial name
- NCT07813117
- Testing
- Zirconium dioxide nano-coated archwire, Conventional orthodontic archwire
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Fluoride Varnishes, Molar Incisor Hypomineralisation
Nanohydroxyapatite Versus Sodium Fluoride Varnish in Remineralizing MIH Anterior Teeth
This randomized controlled clinical trial evaluates and compares the remineralization efficacy of a 8.6% nanohydroxyapatite (nano-HAp) varnish versus a standard 5% sodium fluoride (NaF) varnish in young permanent anterior teeth…
- Conditions
- Fluoride Varnishes, Molar Incisor Hypomineralisation, Permanent Anterior Teeth, Remineralization
- Trial name
- NCT07894510
- Testing
- Nanohydroxyapatite Varnish Application, Sodium Fluoride Varnish Application
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tanta University
Dental Caries, Tooth Injuries
Luting Cements for Prefabricated Zirconia Crown Retention in Primary Anterior Teeth in Children
The goal of this clinical trial is to compare the long-term clinical performance of three different luting cements used to bond prefabricated zirconia crowns (PZCs) on primary front teeth in young children.
- Conditions
- Dental Caries, Tooth Injuries, Primary Tooth Restoration
- Trial name
- NCT07611734
- Testing
- Cementation with Fuji IX GP Extra Glass Ionomer Cement, Cementation with BioCem™ Universal BioActive Cement, Cementation with RelyX™ Universal Resin Cement
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Murad Alrashidi
Tooth Injuries, Dental Restoration, Permanent
Colour Match, Stability, and Patient's Satisfaction of Single-Shade Composites in Anterior Teeth
The goal of this observational study is to evaluate the clinical performance of a single-shade composite resin, used with an injection moulding technique, in restoring maxillary incisors affected by traumatic dental injury in…
- Trial name
- NCT07309653
- Where
- Thailand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mahidol University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
EFFICACY OF BIOMIN FLUORIDE VERSUS SODIUM FLUORIDE VARNISHES, WITH AND WITHOUT DIODE LASER ON WHITE SPOT LESIONS REMINERALIZATION IN PRIMARY TEETH.
The goal of this randomized controlled clinical trial is to assess and compare the remineralizing effect of Biomin fluoride varnish and conventional 5% sodium fluoride varnish (Duraphat), with and without adjunctive low-level…
- Trial name
- NCT07845110
- Testing
- BioMin® fluoride varnish: 5% NaF varnish incorporating bioactive glass (calcium/phosphate releasing)., (BioMin® + Diode Laser), (Duraphat varnish + Diode laser)
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Yassmin Mohamed
Dental Restoration, Permanent, Dental Caries (Disorder)
Effect of Phosphoric Acid Etching Duration on Direct Resin-Based Composite Restorations in Permanent Anterior Teeth
The goal of this clinical trial is to learn if reducing the phosphoric acid etching (PAE) time affects the performance of direct resin-based composite (RBC) restorations in permanent anterior teeth.
- Conditions
- Dental Restoration, Permanent, Dental Caries (Disorder), Dental Restoration Failure
- Trial name
- ETCH-PRO (NCT06991842)
- Testing
- Permanent dental restoration
- Where
- Switzerland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Florin Eggmann
Chronic Apical Periodontitis, Pulp Necrosis
Clinical and Inflammatory Outcomes of Regenerative Endodontic Treatment Using Injectable Platelet-Rich Fibrin in Mature Necrotic Teeth With Chronic Apical Periodontitis.
This randomized clinical trial aims to compare regenerative endodontic treatment using injectable platelet-rich fibrin (i-PRF) with conventional root canal treatment in mature necrotic anterior teeth with chronic apical…
- Trial name
- REGEN-iPRF (NCT07913399)
- Testing
- Conventional Root Canal Treatment, Regenerative Endodontic Treatment with i-PRF, Injectable Platelet-Rich Fibrin (i-PRF)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Stage IV Periodontitis, Orthodontic Tooth Movement
Effect of MOPs During Orthodontic Movement in Periodontitis Patients
Micro-osteoperforations (MOPs) cause cortical bone injuries and consequently increase the expression of inflammatory mediators, allowing for increased bone and periodontal ligament remodeling associated with orthodontic movement.
- Trial name
- MOPorthoperi (NCT06068270)
- Testing
- Micro-ostoperforations (MOPs)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universidad Complutense de Madrid
Correlation of the of the Mandibular to theMaxillary
Correlation of the Mesio-Distal Widths of the Mandibular to the Maxillary Anterior Teeth
Calculation of Mesiodistal width of maxillary and mandibular anterior teeth : 1. Scan the patient's maxillary and mandibular arches to obtain digital casts using an intraoral scanner. 2.
- Trial name
- NCT07734571
- Testing
- Correlation of the Mesio-Distal Widths
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Efficacy of a Novel Nanoparticle -Augmented Disinfection Protocol
The ultimate biological aim of endodontic therapy is to either prevent or heal apical periodontitis. Root canal treatment can fail for various reasons, such as persistent infection, missing canals, ledges, canal transportation…
- Trial name
- NCT07800403
- Testing
- Novel Nanoparticle
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Minia University
CLASS II DIVISION 1 MALOCCLUSION
EVALUATION OF TREATMENT CHANGES IN CLASS II DIVISION 1 MALOCCLUSION DURING EN MASSE RETRACTION OF UPPER ANTERIOR TEETH USING MINI IMPLANTS PLACED AT INFRAZYGOMATIC CREST AND INTERRADICULAR SITES A RANDOMIZED CLINICAL TRIAL.
Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable.
- Trial name
- NCT07405905
- Testing
- retraction of anterior teeth using mini implants placed at infrazygomatic crest., retraction of anterior teeth using mini implants placed at interradicular sites.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Malocclusion of Anterior Teeth
Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study
This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth…
- Trial name
- LLLT (NCT07286474)
- Testing
- Cholecalciferol (Vit D3), Low-Level Laser Therapy, Fixed Orthodontic Appliance
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Malocclusion of Anterior Teeth, Malocclusion in Children
Patient-Reported Outcomes for Different Orthodontic Thermoplastics Used in Clear Aligners
Clear aligner therapy is an esthetic orthodontic treatment modality that uses removable thermoplastic trays to correct dental alignment.
- Conditions
- Malocclusion of Anterior Teeth, Malocclusion in Children, Malocclusion Class II
- Trial name
- NCT07790315
- Testing
- Device / orthodontic clear aligner material
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Malocclusion of Anterior Teeth
Effect of Local Use of Vitamin D on the Rate of Canine Distillization: a Split Mouth Randomized Control Trial
Orthodontic treatment (OT) is characterized as a lengthy procedure and enormous effort has been harnessed to shorten the OT duration using either surgical or non-surgical approaches.
- Trial name
- NCT07479290
- Testing
- Experimental: 1,25 DHC injection
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Periodontitis
Comparison of Replantation and Splinting Alone in Lower Anterior Teeth
Replantation is defined as the intentional extraction and repositioning of teeth that have lost their periodontal support. The aim of this study is to evaluate the clinical and radiographic follow-up results of planned…
- Trial name
- NCT07141680
- Testing
- Replantation, Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Modified Fixed Bridge
3D Printed vs CAD/CAM Rehabilitation of Primary Anterior Teeth Loss
compare 3D Printed versus CAD/CAM fabricated modified fixed appliance for rehabilitation of premature loss of anterior teeth in preschool children
- Trial name
- NCT07752147
- Testing
- 3D Printed modified fixed bridge, CAD/CAM fabricated modified fixed bridge
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Tooth Fractures (Class IV), Composite Resins
Evaluation of Clinical Performance, Shade Matching, and Patient Satisfaction of Different Resin Composite Layering Techniques Using 3D Printed Cast
The aim of this randomized clinical trial is to compare different resin composite layering techniques (monochromatic, complex multichromatic, and single-shaded structurally-colored composite) using 3D printed casts for the…
- Conditions
- Tooth Fractures (Class IV), Composite Resins, Permanent Anterior Teeth
- Trial name
- NCT07813949
- Testing
- Resin Composite Layering Techniques using 3D Printed Casts
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic, Retainer
Comparison Between Periodontal Effects of Fixed and Vacuum-Formed Retainers
One of the most crucial aspects of orthodontic therapy is retention, which is required to prevent orthodontic relapse . There are two main types of retainers, removable retainer which depends on patient compliance to achieve…
- Conditions
- Orthodontic, Retainer, Periodontal Health
- Trial name
- NCT07650630
- Testing
- Fixed retainer, vacuum retainer
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Cross Bite
Evaluation of Myobrace for Crossbite Correction in Mixed Dentition
This randomized controlled clinical trial will evaluate the effectiveness of the Myobrace appliance in correcting anterior and posterior crossbite in children aged 6 to 10 years during the mixed dentition stage.
- Trial name
- Myo vs Frankel (NCT07840053)
- Testing
- Myobrace Interceptive Class III Appliance, Frankel III Functional Regulator
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University