Clinical trials: Mammary Cancer
Breast Cancer
Factors Affecting Rehabilitation Time for Postoperative Complications Among Breast Cancer Patients
Breast cancer patients who had undergone surgery, chemotherapy and radiotherapy suffered from complications, including shoulder stiffness, lymphedema and scar contracture. These symptoms impaired one's ADL function.
- Trial name
- NCT05401877
- Testing
- therapies for breast cancer
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Taichung Veterans General Hospital
Breast Cancer-Related Lymphedema, Lymphedema
Supermicrosurgical Lymphaticovenous Anastomosis for Prevention of Upper Limb Lymphedema
Breast cancer-related lymphedema (BCRL) is one of the most common chronic complications following breast cancer treatment. This study enrolls breast cancer patients who are required to undergo axillary lymph node dissection and…
- Conditions
- Breast Cancer-Related Lymphedema, Lymphedema, Breast Cancer Invasive
- Trial name
- SLVA-PULL (NCT07026292)
- Testing
- Immediate Distal Lymphaticovenous Anastomosis (ID-LVA)
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Breast Cancer Female
EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Breast CA
The goal of this clinical trial is to learn how a group resistance training plan can improve body mobility and strength in female breast cancer patients who have completed their breast cancer treatment.
- Trial name
- EXERT-BC (NCT05747209)
- Testing
- Observation of Exercise Program Adherence
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Colin Champ, MD
Breast Cancer, Prostate Cancer
A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT).
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT07225309
- Testing
- Meaning-Centered Psychotherapy for Latinos /MCP-L
- Where
- 2 sites in United States, Mexico
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
A Study to Investigate the Tolerability of Subcutaneous (SC) Trastuzumab Administration in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Early Breast Cancer (eBC) Using Either a Single-Use Injection Device or Manual Administration
This multicenter study in participants with HER2-positive eBC will investigate participants' pain and discomfort of SC trastuzumab (Herceptin) administered either via a single-use injection device (SID) or via vial for manual…
- Trial name
- ESCAPE (NCT02194166)
- Testing
- Trastuzumab, Paclitaxel, Docetaxel
- Where
- 7 sites in Belarus, Kazakhstan
- Volunteers
- 90 people
- Sponsor
- Hoffmann-La Roche
Malignant Neoplasm of Breast
Neoadjuvant Pembrolizumab(Pbr)/Nab-Paclitaxel Followed by Pbr/Epirubicin/Cyclophosphamide in TNBC
Despite its aggressiveness and high incidence, to date, no targeted therapies exist for the treatment of triple negative breast cancer (TNBC).
- Trial name
- NIB (NCT03289819)
- Testing
- Pembrolizumab, nab-paclitaxel, Epirubicin
- Where
- 4 sites in Germany
- Volunteers
- 53 people
- Sponsor
- Institut fuer Frauengesundheit
Survival Outcomes
Effectiveness of Surgery for Improving Survival in Oligometastatic Breast Cancer Patients
Breast cancer is the most common malignancy in women, with stage IV disease at diagnosis in 5-10% of cases. Oligometastatic breast cancer (OMBC), defined as limited metastases (≤3-5 in ≤1-2 organs), may have better outcomes.
- Trial name
- SASI-MBC (NCT07586319)
- Testing
- surgery in accordance with current clinical guidelines, modified radical mastectomy or breast conservation surgery
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Sharif Medical Research Center
Chemotherapy-induced Neutropenia
Balugrastim (Neugranin) in Breast Cancer Participants Receiving Doxorubicin/Docetaxel
Determination of the effect of balugrastim on the duration and severity of severe neutropenia.
- Trial name
- NEUGR-002 (NCT00837265)
- Testing
- Balugrastim, Pegfilgrastim, Chemotherapy Regimen
- Volunteers
- 334 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
DCIS
Management of Low-risk (Grade I and II) DCIS
A substantial number of DCIS lesions will never form a health hazard, particularly if it concerns slow-growing low-risk DCIS (grade I and II).
- Trial name
- LORD (NCT02492607)
- Testing
- Standard treatment, digital mammography, radiotherapy
- Where
- 60 sites in Netherlands
- Volunteers
- 2,500 people
- Sponsor
- The Netherlands Cancer Institute
Breast Cancer
A Study of Pemetrexed and Cyclophosphamide Given Every 21 Days in Advanced Breast Cancer Patients
This is the phase 2 portion of a phase 1/2 trial, testing the use of pemetrexed and cyclophosphamide in combination for the treatment of advanced breast cancer.
- Trial name
- NCT00190671
- Testing
- pemetrexed, cyclophosphamide
- Where
- 13 sites in Austria, Czechia and 4 more
- Volunteers
- 103 people
- Sponsor
- Eli Lilly and Company
Obesity, Colorectal Cancer
Prevention of Obesity-related Cancers: Setting up of a Multi-Cancer Education and Prevention Program in Hong Kong
Obesity could increase the risk of many chronic diseases, including hypertension, cardiovascular diseases, high lipid level, diabetes, stroke, endometrial cancer and certain types of cancer which could benefit by secondary…
- Conditions
- Obesity, Colorectal Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT04034953
- Testing
- Faecal Immunochemical Test, Prostate-Specific Antigen Test, Mammogram
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Metastatic Breast Cancer
Phase II PEMBROLIZUMAB + PALLIATIVE RADIOTHERAPY IN BC
This research study is studying radiation therapy in combination with an immunotherapy as a possible treatment for metastatic hormone receptor (HR) positive, HER2-negative breast cancer.
- Trial name
- NCT03051672
- Testing
- Pembrolizumab, Palliative radiotherapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Randomized Trial of Follow-up Strategies in Breast Cancer
The purpose of this study is to determine whether family physician 'routine follow-up care' of women with breast cancer in remission is an acceptable alternative to the existing system of specialist follow-up.
- Trial name
- NCT00156039
- Testing
- Follow-up Strategy for Breast Cancer
- Where
- 5 sites in Canada
- Volunteers
- 968 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer
The SONImage Study
SONImage is a multicenter prospective imaging side study, in which a baseline FES-PET is added to conventional work up, in 100 patients with ER+ MBC who will receive endocrine treatment ± CDK 4/6 inhibition within the SONIA study…
- Trial name
- SONImage (NCT04125277)
- Testing
- FES-PET scan, and possibly one additional visit for an FDG-PET
- Where
- 2 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- The Netherlands Cancer Institute
Depressive Symptoms, Cognitive Impairment
Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)
The goal of this clinical trial is to test a home-delivered intervention that combines Non-Invasive Brain Stimulation techniques (transcranial direct and alternating current stimulation -tDCS and tACS-) and Online Cognitive…
- Trial name
- ONCODEP (NCT06053775)
- Testing
- Transcranial Direct Current Stimulation, Transcranial Alternating Current Stimulation, Online Cognitive Training
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- University of Santiago de Compostela
Breast Cancer Survivors
The Effect of Myofascial Chain Release Techniques on Shoulder Joint Range of Motion in Breast Cancer Survivors
In breast cancer patients, limitation of shoulder joint movement occurs following mastectomy surgery. Studies have reported that damage to the fascia on the pectoralis major muscle during mastectomy surgery contributes to the…
- Trial name
- NCT05386628
- Testing
- conventional physiotherapy, Manual lymphatic drainage, Myofascial relasing
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Medeniyet University
Breast Cancer, Alcohol Drinking
Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits
This study is a single-arm feasibility trial evaluating a digital behavioral intervention designed to increase women's awareness of the relationship between alcohol use and breast cancer risk during routine breast cancer…
- Trial name
- NCT07799467
- Testing
- Sobriety Digital Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Miami
Risk Reduction Behavior
Self-Affirmation: Construct Validity
Background: People respond differently when asked about their values. They also respond differently when they learn about how their actions affect their lives and health. Researchers want to learn more about these differences.
- Trial name
- NCT02317367
- Where
- United States
- Volunteers
- 3,112 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Metastatic Breast Cancer
A Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Chemotherapy in Untreated Metastatic Breast Cancer (RIBBON 1)
This is a Phase III, multicenter, randomized, placebo-controlled trial designed to evaluate the efficacy and safety of bevacizumab in combination with chemotherapy compared with chemotherapy alone in subjects with previously…
- Trial name
- NCT00262067
- Testing
- Bevacizumab, Chemotherapy
- Where
- 92 sites in United States, Australia and 20 more
- Volunteers
- 1,237 people
- Sponsor
- Genentech, Inc.
Breast Cancer, Precancerous Condition
Broccoli Sprout Extract in Treating Women Who Have Had a Mammogram and Breast Biopsy
RATIONALE: Broccoli sprout extract supplements may slow the growth of tumor cells or abnormal cells and may be an effective treatment for ductal carcinoma in situ and/or atypical ductal hyperplasia.
- Trial name
- NCT00843167
- Testing
- broccoli sprout extract
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- OHSU Knight Cancer Institute
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