Clinical trials: Management, Risk
Diabetes Mellitus, Type 1
Diabetes Technology Study of Real-Time Glucose Alerts in the Team Management of Diabetes
Many people with diabetes have a desire to share blood glucose data with other members of their team. Using a unique wireless glucose meter device, real-time wireless alerts may be automatically sent to a specific team of…
- Trial name
- NCT00322478
- Testing
- Automated informatics driven education and social networking, Blood Glucose Notifications to Remote Caregivers, Frequency of Pattern Management
- Where
- United States
- Volunteers
- 432 people
- Sponsor
- Diabetech
Osteoporosis
Qualitative Study on Osteoporosis Representation and Management in the General Population and in General Practitioners.
Osteoporosis (OP) and subsequent fractures (OP fractures) are a source of morbidity and high mortality in the elderly. Despite numerous programs aiming at improving OP care, the prevention, diagnostic and treatment remain…
- Trial name
- QUALIOP (NCT02861989)
- Testing
- qualitative study
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Hospices Civils de Lyon
Acute Cholecystitis, Choledocholithiasis
Acute Cholecystitis With Concomitant Choledocholithiasis: Unicentric Study of Prevalence and Predictive Factors
The management of cholelithiasis with choledocolithiasis is extensively known, whereas for Acute Calculous Cholecystitis (ACC) with choledocolithiasis or common bile duct stones (CBDS), a common entity, there is a lack of…
- Trial name
- CHOLEPREV (NCT04739891)
- Volunteers
- 120 people
- Sponsor
- Hospital de Mataró
Upper Gastrointestinal Bleeding
Patients With Upper Gastrointestinal Bleeding in Emergency Department
More than 80% of patients with upper gastrointestinal bleeding (UGIB) are hospitalized after their visit to the emergency department (ED). However, some of these hospitalizations do not seem justified.
- Trial name
- UGIB-ED (NCT05927493)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer Survivorship, Weight Management
Weight Management After Cancer for Survivors in Rural Communities
This study is testing a new program called WeCan-Rural, designed to help breast cancer survivors manage symptoms and build healthy habits like eating well, staying active, and managing their weight.
- Conditions
- Breast Cancer Survivorship, Weight Management, Cardiovascular (CV) Risk, Breast Cancer
- Trial name
- WeCan-Rural (NCT07426952)
- Testing
- WeCan-Rural Program
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Ventilator-Induced Lung Injury
Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA
Lung protective ventilation (LPV) has been proposed to reduce the incidence of postoperative pulmonary complications (PPCs), and protect against ventilator induced lung injury (VILI).
- Trial name
- NCT03135691
- Where
- United States
- Sponsor
- Ohio State University
Cannabis, Cardiovascular Risk Factor
Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise
This two-phase project seeks to examine the cardiovascular response to consumption of cannabis variants of different cannabinoid composition through different methods (smoking vs. vaporizing), at rest and during aerobic exercise.
- Trial name
- NCT04693884
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jamie Burr
Tumor, Stroke
Different Intraoperative Blood Pressure Management on Postoperative Cognitive Function in Tumor Patients（PRECISION）
This is a randomized controlled study to explore whether perioperative blood pressure management with different strategies can reduce the incidence of delirium and postoperative cognitive impairment and serious perfusion related…
- Trial name
- PRECISION (NCT06711432)
- Testing
- Norepinephrine or phenylephrine
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Zhejiang Cancer Hospital
Coronary Syndrome, Acute, Non-ST Elevation, High Risk Patients
Management Tactics for Patients High Risk With Acute Coronary Syndrome Without ST Segment Elevation and Multivessel Coronary Artery Disease
The study will include patients with acute coronary syndrome without ST segment elevation and multivessel CA lesion, who are subject to surgical treatment according to KG data (Syntax Score 23 - 32 points with significant damage…
- Trial name
- NSTE-ACSMT (NCT06279663)
- Testing
- Revascularization
- Where
- 2 sites in Russia
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Institution National Medical Research Center named after academician E.N. Me
Quality of Life
Patient-Centred Care for Warfarin Management: A Pilot Study to Transition Care to High Risk Patients
Warfarin remains the only oral anticoagulant effective in preventing stroke and valve thrombi for patients having mechanical heart valves (MHVs).
- Trial name
- NCT03295799
- Testing
- Patient Self-Management
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- University of Alberta
Dental Caries
Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child
Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy. Hypothesis: the administration of probiotics during infancy has no effect on future dental health.
- Trial name
- NCT01424852
- Testing
- Probiotics in infant milk formula
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Turku
Gambling Disorder
Contingency Management as an Adjunct Treatment for Rural and Remote Disordered Gamblers
The purpose of this project is to pilot contingency management as an adjunct treatment to counselling as usual using internet delivered video-conferencing applications for remote disordered gamblers.
- Trial name
- NCT02953899
- Testing
- Contingency Management, Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Choledocholithiasis
"Endoscopy First" or "Laparoscopic Cholecystectomy First" for Patients With Intermediate Risk of Choledocholithiasis
The study compares two different methods to evaluate extrahepatic bile ducts for possible stones for patients with cholecystolithiasis and intermediate risk for choledocholithiasis when laparoscopic cholecystectomy is indicated.
- Trial name
- NCT03658863
- Testing
- endoscopic ultrasound, intraoperative cholangiography, ERCP
- Where
- Lithuania
- Volunteers
- 106 people
- Sponsor
- Vilnius University
Genetic Predisposition to Disease, Genetic Predisposition
Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing
This research is being done to develop the electronic platform Nest for young adults (ages 18-39) who have had prior cancer genetic testing.
- Trial name
- NCT05759143
- Testing
- Nest Platform
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer
The Active Surveillance Study
The Active Surveillance study is a prospective study developed to look at the association of biomarkers with PrCa presentation and progression among men on Active Surveillance and stratify it by their genetic risk.
- Trial name
- AS (NCT05810467)
- Testing
- Active Surveillance
- Where
- 4 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Suicide Prevention
Bridge the Gap (BTG) - Black Youth Group
The goal of this clinical trial is to develop and preliminarily test a culturally adapted suicide intervention specifically for black youth.
- Trial name
- Bridge the Gap (NCT06880809)
- Testing
- Bridge the Gap (BTG) - Black Youth Group
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Surgical Site Occurences After Sternotomy, Wound Infection
The Use of PrevenaTM on Clean Closed Sternal Midline Incisions in Subjects at High Risk for Surgical Site Occurrences.
The purpose of this study is to compare the use of Prevena™ Incision Management System (IMS) versus standard wound care for the incision in subjects undergoing a sternal midline incision (sternotomy).
- Trial name
- NCT02195310
- Testing
- Prevena™ Incision Management System, Conventional sterile wound dressings
- Where
- 13 sites in Austria, Germany and 1 more
- Volunteers
- 342 people
- Sponsor
- Solventum US LLC
Self-management for Mobility Improvement in the Elderly
The Senior Step Study How Elderly Help Themselves Maximally Forward
The Senior Step Study investigates whether feedback given by a mobility feedback device in combination with an instruction book containing every day exercises, motivates elderly to exercise more.
- Trial name
- SSS (NCT01792180)
- Testing
- Mobility feedback device with use of instruction book
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Radboud University Medical Center
Covid-19 (SARS-CoV-2)
Ambulatory Management of Moderate to High Risk COVID-19 (SARS-CoV-2) Patients - The Coronavirus Related Outpatient Work Navigators (CROWN) Protocol
Descriptive report of the Northwell CROWN program for ambulatory treatment of COVID-19 (SARS-CoV-2) patients with moderate to high risk features
- Trial name
- CROWN (NCT04476602)
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Northwell Health
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Megakaryoblastic Leukemia (M7)
Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
This randomized phase II trial is studying two different schedules of alvocidib to compare how well they work when given together with cytarabine and mitoxantrone in treating patients with newly diagnosed acute myeloid leukemia.
- Conditions
- Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a)
- Trial name
- NCT00795002
- Testing
- alvocidib, mitoxantrone hydrochloride, cytarabine
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- National Cancer Institute (NCI)