Clinical trials: Management, Risk
Periodontitis, Cardiovascular Risk Factor
Relationship Between Nutritional Status, Physical Activity and Periodontal Status
This observational retrospective study aims to evaluate the relationship between nutritional status, physical activity levels, and periodontal health in adult patients.
- Conditions
- Periodontitis, Cardiovascular Risk Factor, Metabolic Risk Factors, Physical Activity
- Trial name
- NAP-Perio (NCT07496710)
- Where
- Spain
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Obesity and Overweight, Obese Adolescents
Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
The goal of this clinical trial is to learn if the drug semaglutide changes markers of disease risk as it relates to weight in children ages 12-15 years old who are obese (class 2 or 3).
- Conditions
- Obesity and Overweight, Obese Adolescents, Weight Management, Weight Loss
- Trial name
- MODERN (NCT06967389)
- Testing
- Ozempic®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- John Bauer
Acromegaly, Growth Hormone Deficiency
Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency
The purpose of the study is to evaluate the effects of growth hormone (GH) replacement in men and women with a history of acromegaly and who are now growth hormone deficient.
- Conditions
- Acromegaly, Growth Hormone Deficiency, Pituitary Disease
- Trial name
- NCT00182091
- Testing
- Recombinant human growth hormone, Saline
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Stroke, Cerebrovascular Disorders
Comprehensive Management of High-risk PopuLatIon for Stroke Based on Social Network
The purpose of this study is to evaluate the effectiveness of social network in improving drug compliance and risk factors control rate of stroke high-risk population after discharge.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- COMPLIANCE-MT (NCT05963828)
- Testing
- conventional care, Social network-based intervention
- Where
- China
- Volunteers
- 720 people
- Sponsor
- Changhai Hospital
Stroke, Ischemic Attack, Transient
Post-Stroke Disease Management - Stroke Card
Patients after ischemic stroke are at high risk of recurrent cardiovascular events and of developing post-stroke complications. There is a substantial gap between risk factor management in real life and that recommended by…
- Conditions
- Stroke, Ischemic Attack, Transient, Secondary Prevention, Disease Management
- Trial name
- Stroke Card (NCT02156778)
- Testing
- Active Comparator: Extended Standard Care (Stroke Card), Active Comparator: Standard Care
- Where
- Austria
- Volunteers
- 2,149 people
- Sponsor
- Medical University Innsbruck
Lumbar Disc Herniation, Obstructive Sleep Apnea Risk Management
Daytime vs Evening Rehabilitation in Lumbar Disc Herniation Patients at High Risk for Obstructive Sleep Apnea
Lumbar disc herniation is a common musculoskeletal condition that negatively affects quality of life, physical function, and daily activities.
- Trial name
- REHAB-TIME (NCT07522021)
- Testing
- Physiotherapy and Exercise Program
- Volunteers
- 60 people
- Sponsor
- Mardin Artuklu University
Diabetes Mellitus, High Blood Pressure
Comparative Effectiveness of Family vs. Individually Focused Diabetes Education and Support
The objective of this study is to compare the effectiveness of a novel program-Family Support for Health Action (FAM-ACT) - to individual patient-focused diabetes self-management education and support (I-DSMES).
- Conditions
- Diabetes Mellitus, High Blood Pressure, High Blood Sugar, Hypertension
- Trial name
- NCT03812614
- Testing
- FAM ACT, I-DSMES
- Where
- 2 sites in United States
- Volunteers
- 444 people
- Sponsor
- University of Pittsburgh
Chronic Disease of Cardiovascular System
Remote Monitoring of Chronic Illness Patients With a IHAP Home Wireless Hub and Vitals Measurements
This is planned as a feasibility study. The primary objective is to evaluate a specially designed patient monitoring software Vitalbeat and standard mobile device hub termed Intel Health Application Platform (IHAP) in terms of…
- Trial name
- REMOTE-HUB-1 (NCT06330714)
- Testing
- Symptoms of chronic illness.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Aventyn, Inc.
Hypertension
Enhancing the Risk Assessment and Management Program by Promotion of Self-blood Pressure Monitoring
Clinical Trial: The investigators aims at comparing providing validated home BP device, followed by group education of self-management of hypertension as well as self-BP monitoring and appropriate medication in response to home…
- Trial name
- NCT02551393
- Testing
- Home Blood Presssure Monitoring, Education
- Volunteers
- 291 people
- Sponsor
- The University of Hong Kong
Hiv, Meningitis, Meningococcal
Evaluation of Safety and Immunogenicity of Meningococcal B and Meningococcal ACWY Vaccine in at Risk Population
This study aims to evaluate the immunogenicity, safety and tolerability of co-administration of vaccinations for meningitis B (Bexsero®) and meningitis ACWY (Menveo®) in adults and children aged 10-45 years living with HIV.
- Conditions
- Hiv, Meningitis, Meningococcal, HIV Infections
- Trial name
- ProPositive (NCT03682939)
- Testing
- Bexsero® (meningitis B vaccine), Menveo® (meningitis ACWY vaccine)
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- St George's, University of London
Low Risk, Papillary Thyroid Cancer
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.
- Conditions
- Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
- Trial name
- NCT07140757
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Polyhydramnios
Amnioreduction in Polyhydramnios
The aim of this work is to review the indications, procedural complications and outcomes of amnioreduction in pregnancies complicated by polyhydramnios.
- Trial name
- NCT07067593
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Assiut University
Covid19
suPAR-Guided Anakinra Treatment for Management of Severe Respiratory Failure by COVID-19
The SAVE-MORE is a pivotal, confirmatory, phase III randomized clinical trial (RCT) aiming to evaluate the efficacy and safety of early start of anakinra guided by suPAR in patients with LRTI by SARS-CoV-2 in improving the…
- Trial name
- SAVE-MORE (NCT04680949)
- Testing
- Anakinra
- Where
- 40 sites in Greece, Italy
- Volunteers
- 606 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Colonic Disease
Performance of the Poseidon System for Fluid Management During Water-aided Colonoscopy
To validate the performance of the Poseidon System™ for fluid management during water-aided endoscopic procedures in the colon.
- Trial name
- NCT05512026
- Testing
- Feasibility Assessment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- WAE Medical
Childhood Obesity
Role of Carbohydrate Modification in Weight Management Among Obese Children
The purpose of this study is to test the hypothesis that a low-carbohydrate diet and a low-glycemic load diet will improve body mass index and result in more body fat loss than a control diet among overweight children ages 7 to…
- Trial name
- NCT00215111
- Testing
- Low carbohydrate, reduced glycemic load, and a control diet
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Risk Reduction
Cultural Competency, Risk Management, and Patient Safety Internet-Based Curriculum for OB/GYN Resident Physicians
Additional educational training lectures were provided to healthcare workers. Outcome measure of cultural competency was completed to assess patient safety, risk management, and cultural competency of healthcare providers in an…
- Trial name
- PROM (NCT02355847)
- Testing
- Lectures
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Brett Worly, MD
Metastatic Breast Cancer
Prospective Observational Study in Patients With Metastatic Breast Cancer Treated With Anthracyclines
This is an open, multicentre, prospective observational (non-interventional) study, performed in Belgium. Principal objectives: 1.
- Trial name
- NCT01555944
- Where
- 24 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Teva Pharma
Lung Cancer, High-Risk Cancer
Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration
Lung cancer is the leading cause of mortality in the world, and also in Taiwan.Despite the researches and availability in new therapies, it causes the highest mortality and is one of the most preventable cancers as well.
- Conditions
- Lung Cancer, High-Risk Cancer, Smoking, Pollution; Exposure
- Trial name
- TRIO (NCT05557487)
- Testing
- Low dose computed tomography
- Where
- 7 sites in Taiwan
- Volunteers
- 6,618 people, healthy volunteers welcome
- Sponsor
- Gee-Chen Chang
Stress Urinary Incontinence (SUI)
Evaluating SUI-100™, A Non-Invasive Device for the Treatment of Stress Urinary Incontinence
The goal of this pivotal clinical trial is to evaluate the safety and effectiveness of the SUI-100 device for the treatment of mild-to-moderate stress urinary incontinence (SUI) in females aged 22-70 years.
- Trial name
- SaHARA (NCT06862648)
- Testing
- Acoustic Stimulation Therapy Device
- Where
- 9 sites in United States
- Volunteers
- 130 people
- Sponsor
- Acoustic Wave Cell Therapy, Inc.
Obesity
Effect of a Unique Web-based Behaviour Change Program on Weight Loss and Cardiovascular Risk Factors
Web- or internet-based programs have the potential to induce and, possibly, help to sustain, significant lifestyle modification.
- Trial name
- NCT01472276
- Testing
- Web-based program
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast