Clinical trials: Management, Risk
Contrast Agent, Nausea
Immediate Nausea and Vomiting After the Administration of Non-ionic Contrast Media
The prevalence of nausea and vomiting after the administration of non-ionic contrast media has rarely been assessed. Thus, the aim of our study is to evaluate the prevalence and risk factors of nausea and vomiting after the…
- Trial name
- NCT03019341
- Where
- South Korea
- Volunteers
- 1,175 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease Risk Factors Multiple, Coronary Artery Disease Progression
PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
Heart disease is the leading cause of death for men, women, and people of most racial and ethnic groups in the United States. This clinical trial will test if screening and early treatment of mild heart disease works.
- Conditions
- Coronary Artery Disease Risk Factors Multiple, Coronary Artery Disease Progression, Prevention & Control, Premature Atherosclerosis
- Trial name
- PRE-EMPT (NCT07232069)
- Testing
- Rosuvastatin 20 Mg Oral Tablet, Colchicine 0.5 MG Oral Tablet Once Daily
- Where
- 23 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Duke University
Alcohol Drinking
The College, Alcohol and Peers Study (CAPS)
The present study will evaluate college students (N=100) from 2- and 4-year colleges/universities between 21-24 years old to assess anxiety, affect, broad social motives (BSM) and peer group influences on drinking and other…
- Trial name
- NCT03890484
- Testing
- Peer Type - New Peer, Peer Type - Close Friends
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cardiovascular Disorder, Chronic Kidney Disease
Cancer and Blood Pressure Management, CARISMA Study
This phase II trial studies how well intensive blood pressure management works in decreasing systolic blood pressure in patients with kidney or thyroid cancer that has spread to other places in the body (metastatic) who are…
- Conditions
- Cardiovascular Disorder, Chronic Kidney Disease, Metastatic Renal Cell Carcinoma, Metastatic Thyroid Gland Medullary Carcinoma
- Trial name
- NCT04467021
- Testing
- Best Practice, Blood Pressure Measurement, Clinical Management
- Where
- 25 sites in United States
- Volunteers
- 61 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia
This phase I/II studies the side effects and best dose of natural killer cells before and after donor stem cell transplant and to see how well they work in treating patients with acute myeloid leukemia, myelodysplastic syndrome…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia With Gene Mutations, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
- Trial name
- NCT01904136
- Testing
- Allogeneic Hematopoietic Stem Cell Transplantation, Bone Marrow Transplantation, Cyclophosphamide
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- M.D. Anderson Cancer Center
Ventricular Tachycardia
Anesthetic Management in Patients Undergoing Epicardial Ablation
The study is a retrospective study and is descriptive in nature. In this study, the investigators aimed to emphasize the importance of anesthesia management by cardiac risk assessment of patients undergoing epicardial ablation…
- Trial name
- NCT06538987
- Testing
- percutaneous epicardial ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Caries,Dental
Accuracy of ICCMS Versus Simplified Cariogram
The study aims to compare the validity of the caries risk assessment regarding the comprehensive ICCMs Caries risk and likelihood matrix versus the simplified Cariogram aiming to see if there is a significant difference in the…
- Trial name
- NCT06448884
- Volunteers
- 323 people
- Sponsor
- Kirolos Hisham Nadi Sedek
Airway Management
Patient Positioning and Airway Management During ERCP
The aim of this study is to determine the effect of airway management (a set of medical procedures performed to prevent airway blockage and thus ensure an open path between a patient's lungs and the atmosphere) during endoscopic…
- Trial name
- NCT02850887
- Testing
- general endotracheal anesthesia, deep sedation without endotracheal intubation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington University School of Medicine
Covid19
Managerial and Environmental Risk for COVID 19 in French Long Term Care Institutions
REMPAR EHPAD study addresses environmental and managerial factors associated with an outbreak of COVID 19 in French Long Term Care Institutions in the spring of 2020.
- Trial name
- REMPAR-EHPAD (NCT04579289)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Rennes University Hospital
High Risk of Preterm Delivery
Interest of Virtual Reality for the Management of Hospitalized Pregnant Patients at Risk of Preterm Delivery
Patients at high risk of preterm birth are hospitalized with an high stress for their child's future. In order to better prepare the patient to a possible preterm delivery we use to propose her a visit of the neonatology unit.
- Trial name
- OREV (NCT05547724)
- Testing
- Virtual reality
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Limoges
Goal-directed Fluid Therapy, Hemodynamics Instability
Multi-center Trial of Goal-directed Fluid Management Based on Pulse Pressure Variation Monitoring
Background: Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. It was tested this hypothesis in a multi-center study.
- Conditions
- Goal-directed Fluid Therapy, Hemodynamics Instability, High-risk Surgery, Pulse-pressure Variation
- Trial name
- GDTPPV (NCT03128190)
- Testing
- Pulse pressure variation monitoring
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo
Health Behavior, Cardiovascular Diseases
Prospective, Multicenter Study Assessing a Screening Campaign for Cardiovascular Diseases Risk Factors During SARS-CoV-2 Epidemic
The goal of this prospective study is to evaluate the impact of an innovative screening campagn (using the medical device "CONSULT STATION®" on french population healthcare .
- Conditions
- Health Behavior, Cardiovascular Diseases, Cardiovascular Morbidity
- Trial name
- VACCIPREV (NCT05293379)
- Testing
- Connected teleconsultation booth
- Where
- 4 sites in France
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Elsan
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Metabolic Surgery for Atrial Fibrillation Elimination
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is estimated that between 3 and 6 million Americans are currently living with AF, while 12 million people in the United States will have AF in 2030.
- Trial name
- METSAFE (NCT07027969)
- Testing
- Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ali Aminian
Bladder Cancer
Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder Cancer
Patients diagnosed with low risk non-muscle invasive bladder cancer (NMIBC) are at risk of frequent low grade recurrence, which usually necessitates surgical intervention under general anaesthetic.
- Trial name
- CALIBER (NCT02070120)
- Testing
- Mitomycin C, Surgical Management
- Where
- 38 sites in United Kingdom
- Volunteers
- 82 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Carotid Endarterectomy, Coronary Artery Bypass Grafting
Multidisciplinary CAE and CABG Surgery to Optimize the Management of High-risk Patients During the Perioperative Period
This project uses concurrent CEA+CABG combined surgery on high-risk patients with severe carotid artery stenosis and severe coronary artery stenosis.
- Trial name
- NCT04960488
- Testing
- carotid endarterectomy and coronary artery bypass grafting
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Cardiovascular Disease
A Study Exploring the Effect of Adjuvanted RZV or RSVPreF3 Vaccines on Coronary Plaque Progression in Adults >=50 Years of Age at Risk for Cardiovascular Events
This study is designed to evaluate whether the adjuvanted recombinant zoster vaccine (RZV) or the adjuvanted respiratory syncytial virus PreFusion protein 3 (RSVPreF3) vaccine can attenuate the progression of coronary plaque in…
- Trial name
- NCT07712380
- Testing
- Adjuvanted RZV vaccine, Adjuvanted RSVPreF3 vaccine
- Volunteers
- 450 people
- Sponsor
- GlaxoSmithKline
Portal Vein Thrombosis
Risk Factors and Management Outcome of Chronic Portal Vein Thrombosis in Children
The aim of study is to evaluate different etiological and risk factors that lead to chronic portal vein thrombosis and to delineate a management plan for chronic portal vein thrombosis in children.
- Trial name
- NCT06117488
- Testing
- endoscopy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Osteoporosis in Post-menopausal Women, Prevention
Development of a Wearable Device for Osteoporosis Prevention and Fracture Risk Reduction in Women
This project aims to determine the impact on bone health of: A lifestyle intervention promoting impact-based activities and physical activity for nine months. The same program enhanced with home-based strength training.
- Conditions
- Osteoporosis in Post-menopausal Women, Prevention, Exercise, Physical Activity
- Trial name
- Weapom (NCT06741956)
- Testing
- Weapom Lifestyle Intervention to measure bone impacts using a Fitbit Versa wearable device and the Weapom App.
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Seville
COVID-19 Pandemic, Vulnerable Subjects
Perceived Impact of the COVID-19 Pandemic on Medical Management and Symptoms in a High Risk Group
The Swiss population underwent a period of confinement related to the COVID-19 pandemic (March 16 to May 11, 2020) decided by the Swiss Federal Government.
- Conditions
- COVID-19 Pandemic, Vulnerable Subjects, Long-term Non-invasive Ventilation
- Trial name
- NCT04477473
- Testing
- Questionnaire-based observational study
- Where
- Switzerland
- Volunteers
- 66 people
- Sponsor
- University Hospital, Geneva
Hypercholesterolemia
Comparing the Efficacy and Safety of Rosuvastatin With Atorvastatin and Simvastatin (SOLAR)
The purpose of this study is to compare the efficacy and safety of rosuvastatin with simvastatin and atorvastatin in reducing levels of low density lipoprotein cholesterol in subjects with hypercholesterolaemia
- Trial name
- SOLAR (NCT00654173)
- Testing
- Rosuvastatin, Simvastatin, Atorvastatin
- Volunteers
- 4,444 people
- Sponsor
- AstraZeneca