Clinical trials: Management, Risk
Colorectal Cancer, Colorectal Adenocarcinoma
Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection
Colorectal cancers (CRC) extending beyond the muscularis mucosae and invading the submucosa without extending beyond it are classified as pT1.
- Trial name
- PROMOT1 (NCT06339346)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Post-ERCP Acute Pancreatitis
Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acute Pancreatitis
ERCP (endoscopic retrograde cholangiopancreatography) has been largely demonstrated to be effective in multiple bilio-pancreatic indications.
- Trial name
- NCT01855841
- Testing
- Hemin
- Where
- 6 sites in Belgium, Taiwan
- Volunteers
- 284 people
- Sponsor
- Erasme University Hospital
Diabetes Mellitus, Type 1
Effects of Web-Based Health Information on Risk Behavior for Youth With Type 1 Diabetes in College
Adolescence and emerging adulthood are critical periods during which health outcomes may be imperiled for youth with Type 1 Diabetes (T1D).
- Trial name
- NCT02883829
- Testing
- Peer-Based Web-Based Health Information, Provider-Based Web-Based Health Information
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Boston Children's Hospital
Gestational Diabetes Mellitus
MAIN STUDY: Low Glycaemic Index (GI) Diet in the Management of GDM SUB-STUDY: The Breast Milk Sub-Study
MAIN STUDY: Low glycaemic index (GI) diets are recommended by the Canadian Diabetes Association for treating type 1 and 2 diabetes mellitus (DM), but the role of GI in the management of gestational diabetes(GDM)is not yet clear.
- Trial name
- GIinGDM (NCT01589757)
- Testing
- Standard Care, Low GI diet
- Where
- 4 sites in Canada
- Volunteers
- 99 people
- Sponsor
- University of Toronto
Colorectal Disorders
Does a Central Venous Line Reduce Perioperative Fluid Administration?
'Hypothesis-generating' study to assess whether the presence of a central venous line significantly affects the volumes of fluid infused perioperatively in major elective colorectal surgery
- Trial name
- NCT03985111
- Testing
- Central Venous Catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
Mask Ventilation, General Anesthesia
Prediction of Difficult Mask Ventilation Using 3D-Facescan and Machine Learning
The aim of this study is to prove feasibility and assess the diagnostic performance of a machine learning algorithm that relies on data from 3D-face scans with predefined motion-sequences and scenes (MASCAN algorithm), together…
- Trial name
- MASCAN (NCT05411406)
- Where
- Germany
- Volunteers
- 423 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cardiovascular Diseases, Cardiovascular Risk Factor
Using Big Data to Conduct Innovative Cardiovascular Clinical Trials
Traditional randomized clinical trials (RCTs) have provided extremely valuable information on medical therapies and procedures that have changed the way heart diseases are treated.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Dyslipidemias
- Trial name
- NCT04067297
- Testing
- Lipid management toolbox
- Where
- Canada
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical Evaluative Sciences
Chronic Kidney Diseases, Chronic Kidney Insufficiency
The Cost Effectiveness and Evaluation of Disease Management of Chronic Kidney Disease and High Risk Population
This study is being implemented for 3 aims. The first has been to conduct a systematic literatures review on CKD intervention models and their effectiveness. Findings have been adopted in our intervention program.
- Trial name
- NCT02034149
- Testing
- general management, self-management, peer-assisted management
- Where
- Taiwan
- Volunteers
- 411 people
- Sponsor
- China Medical University Hospital
Performance and Safety of an Airway Management Device
Comparison of the BASKA Airway, a Novel Supraglottic Device, to the LMA Airway in Low Risk Female Patients
The investigators have performed a number of studies on novel airway devices, including an observational study on the performance of a new supraglottic airway named Baska mask.
- Trial name
- NCT01482650
- Testing
- supraglottic airway placement and use
- Where
- Ireland
- Volunteers
- 92 people
- Sponsor
- University College Hospital Galway
HIV
Case Management Alternatives for African American Women at High Risk for HIV
The purpose of this study is to test two innovative case management approaches designed to increase linkages and engagement with drug abuse treatment, HIV-related care, and other health services among an underserved population of…
- Trial name
- NCT00780260
- Testing
- strengths-based case management
- Where
- United States
- Volunteers
- 562 people
- Sponsor
- Nova Southeastern University
Ischemic Stroke
AI-Driven Health Management to Prevent Ischemic Stroke in High-Risk Adults
This study will evaluate whether an artificial intelligence (AI)-driven dynamic health management strategy can help prevent ischemic stroke in adults at high risk of stroke.
- Trial name
- AI-ExpoStroke (NCT07779668)
- Testing
- Usual Community-Based Health Management, AI-Driven Dynamic Health Management
- Volunteers
- 26,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Stroke
A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients
Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management.
- Trial name
- NCT05454397
- Testing
- Observational study, no intervention
- Where
- 34 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Child, Only, Chronic Renal Failure in Children
The Effect of a Mobile Game Application on Children With CRF
The aim of this study was to investigate the effect of a mobile game application developed for children with Chronic Renal Failure (CRF) on disease management. The study was a randomized controlled trial.
- Conditions
- Child, Only, Chronic Renal Failure in Children, Gambling, Disease
- Trial name
- NCT07162220
- Testing
- The clinic's routine education program, Mobile game app
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Akdeniz University
Age Related Cataract, Pain Management During Cataract Surgery
Iris Vascular Area Density-Based Preoperative Pain-Risk Screening and Intervention in Second-Eye Cataract Surgery
This clinical trial aims to evaluate the effectiveness of pranoprofen or prednisolone acetate eye drops for pain management in patients undergoing second-eye surgery for age-related cataracts.
- Trial name
- NCT07291089
- Testing
- Pranoprofen eye drops, Prednisolone acetate eye drops, Sodium hyaluronate eye drops
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Arteriosclerosis
Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA)
RATIONALE: Atherothrombosis is a progressive and generalized vascular disease resulting in events leading to myocardial infarction (heart attack), stroke, and vascular death.
- Trial name
- NCT00050817
- Testing
- clopidogrel (SR25990)
- Where
- 32 sites in United States, Argentina and 30 more
- Volunteers
- 15,603 people
- Sponsor
- Sanofi
Covid19, Kidney Transplant Infection
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
Methods: Out of 2000 kidney transplant recipients in our center in Kuwait, collecting data was started for all COVID-19-positive kidney transplant recipients till August 2020.
- Conditions
- Covid19, Kidney Transplant Infection, Risk Factor, Cardiovascular, Immunosuppression
- Trial name
- OMC-KTR (NCT04542954)
- Testing
- Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience from the Middle East
- Where
- Kuwait
- Volunteers
- 104 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
Type 2 Diabetes, Metabolic Syndrome
Clinical Study on the Effect of a Synbiotic on Body Fat Mass
In this trial the effect of a synbiotic consisting of the three different strains of Lactobacillus fermentum and acacia gum (gum arabic) on body fat mass, body weight, long-term glycemia, insulin resistance and other risk factors…
- Conditions
- Type 2 Diabetes, Metabolic Syndrome, Obesity, Abdominal, Obesity, Visceral
- Trial name
- NCT04754464
- Testing
- synbiotic, microcrystalline cellulose
- Where
- 2 sites in Austria, Germany
- Volunteers
- 120 people
- Sponsor
- Slimbiotics GmbH
Infections, Papillomavirus
Post-marketing Study to Assess the Safety of CERVARIX When Used in the United States and in Canada
This study will assess the risk of spontaneous abortion during weeks 1-19 of gestation, and other pregnancy outcomes, in an Exposed vaccinated cohort, i.e.
- Trial name
- NCT01290393
- Testing
- Data collection
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity
Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos
Physician-based primary care has thus far failed to address the obesity epidemic. In this randomized clinical trial of 200 obese patients with heart disease risk factors, the investigators will evaluate the impact of nurse and…
- Trial name
- VAFO (NCT01242683)
- Testing
- Vivamos Activos Fair Oaks Program
- Where
- 4 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hospitalization, Patient Readmission
Intervening With and Improving Care for Patients at Risk for Frequent Hospital Admissions
Patients with frequent hospital admissions account for a disproportionate share of visits and costs. An intervention that can bridge the gap between hospital and community based care for a population of patients with frequent…
- Trial name
- NCT01292096
- Testing
- Provision of extra (care coordination and management) services
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health