Clinical trials: Management, Risk
Type 2 Diabetes Mellitus (T2DM)
2025 Hypoglycemia Early-Warning and Physician-Nurse Collaborative Management Trial in Type 2 Diabetes
The goal of this clinical study is to learn whether a physician-nurse collaborative intervention guided by an Intelligent Hypoglycemia Risk Early-Warning System can reduce hypoglycemia and improve glycemic control in hospitalized…
- Trial name
- NCT07314749
- Testing
- Physician-Nurse Collaborative Intervention Guided by Intelligent Hypoglycemia Risk Early-Warning System, Usual Care
- Where
- China
- Volunteers
- 1,255 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Hypertension
Systemic Arterial Hypertension in Pediatric Age.
We decided to conduct this study because hypertension in childhood increases the risk of developing cardiovascular disease (such as heart attack or stroke) in adulthood, beginning to damage important structures and organs, such…
- Trial name
- IPERTA (NCT06797908)
- Where
- 3 sites in Italy
- Volunteers
- 350 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Sepsis, Severe Sepsis
Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions
The German Quality Network Sepsis is an association trying to improve quality of care for patients with sepsis, severe sepsis and septic shock or being in risc thereof.
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- icosmos (NCT02820675)
- Testing
- structured case analysis, strucured screening "every patient, every shift"
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Center for Sepsis Control and Care, Germany
Renal Failure Chronic Contrast Induced
Effect of a Pre-interventional Diet on Renal Function After Administration of Contrast Agent in Patients at Risk
The aim of this study is to assess the effect of a diet prior to administration of contrast agent in terms of a preventive procedure which leads to an attenuation of the contrast-induced nephropathy (CIN).
- Trial name
- CR_KMN (NCT01879839)
- Testing
- Diet
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Cologne
Obesity
Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos
Physician-based primary care has thus far failed to address the obesity epidemic. In this randomized clinical trial of 200 obese patients with heart disease risk factors, the investigators will evaluate the impact of nurse and…
- Trial name
- VAFO (NCT01242683)
- Testing
- Vivamos Activos Fair Oaks Program
- Where
- 4 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Extravasation of Contrast Media
Risk Prediction Model for Iodinated Contrast Medium Extravasation
This study aims to develop a risk prediction model for iodine contrast agent extravasation from peripheral veins and to implement this model clinically to establish a risk control management system for iodine contrast agent…
- Trial name
- RPMICME (NCT06859242)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Zhang Wenyan
Chronic Kidney Diseases, Chronic Kidney Insufficiency
The Cost Effectiveness and Evaluation of Disease Management of Chronic Kidney Disease and High Risk Population
This study is being implemented for 3 aims. The first has been to conduct a systematic literatures review on CKD intervention models and their effectiveness. Findings have been adopted in our intervention program.
- Trial name
- NCT02034149
- Testing
- general management, self-management, peer-assisted management
- Where
- Taiwan
- Volunteers
- 411 people
- Sponsor
- China Medical University Hospital
Primary Health Care, Health Care Costs
Patient Aligned Care Team (PACT) Intensive Management (PIM) Project
Purpose: Implement a Patient Aligned Care Team (PACT) model that identifies and proactively manages Veterans at the highest risk for hospital admission and death while the patient is still in the ambulatory care setting.
- Trial name
- NCT03100526
- Testing
- PACT Intensive Management
- Volunteers
- 2,210 people
- Sponsor
- Veteran Affairs Office of Patient Care Services
Obesity, Overweight
A Trial of One to One Weight Management in Primary Care
The purpose of this study is to conduct a randomised controlled trial to assess the sustained effects on weight, selected risk factors and sense of well-being of offering individualized weight management advice in the primary…
- Trial name
- NCT00891943
- Testing
- Structured lifestyle support
- Where
- 2 sites in United Kingdom
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Myocardial Infarction
GlObal Secondary Prevention strategiEs to Limit Event Recurrence After Myocardial Infarction. GOSPEL Study
Cardiac rehabilitation programmes are a proven treatment for individuals with recent myocardial infarction, resulting in reduced morbidity and mortality compared to usual care.
- Trial name
- NCT00421876
- Testing
- multifactorial continued educational - behavioural programme
- Where
- 74 sites in Italy, Switzerland
- Volunteers
- 3,200 people
- Sponsor
- Heart Care Foundation
Cisplatin Induced Hearing Loss
Study of OTO-104 in Subjects at Risk From Cisplatin-Induced Hearing Loss
This is a multicenter, Phase 2 study to assess the feasibility, safety and efficacy of OTO-104 given by intratympanic administration in subjects at risk for ototoxicity from cisplatin chemotherapy regimens in the treatment of…
- Trial name
- NCT02997189
- Testing
- OTO-104
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Otonomy, Inc.
Mobile Health Apps, Lifestyle Intervention
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
The goal of this pragmatic randomized controlled trial is to evaluate the effectiveness of an AI-enabled mobile health management application ("Better Pregnancy" app), grounded in the Theory of Planned Behavior, in preventing…
- Conditions
- Mobile Health Apps, Lifestyle Intervention, Prevention, Multi-component Based Behavioral Intervention
- Trial name
- NCT07582068
- Testing
- Multi-component lifestyle intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Cervical Disc Herniation, Cervical Spinal Stenosis
Edge Computing Platform for Spine Health Risk Management Based on IoT Technology
This project proposes to monitor the spinal posture of a person at rest and in motion in real time through a sensor device that contains spinal health monitoring as its core.
- Conditions
- Cervical Disc Herniation, Cervical Spinal Stenosis, Ossification of Posterior Longitudinal Ligament, Neckbrace Device
- Trial name
- NCT06092138
- Testing
- Wearable Device
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Infant, Cerebral Palsy
Early Support and Physiotherapy for Children and Their Motor Skills
The App-eMot-Quali project proposed here is the first phase in the implementation of a care pathway supported by a digital tool.
- Conditions
- Infant, Cerebral Palsy, Neonatal
- Trial name
- App-eMot-Quali (NCT04523441)
- Testing
- Focus group, Semi-directive interview
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Osteoporosis, Fracture
Mobile Device to Help FRAX® Screening
Background: The Taiwanese FRAX® (Fracture Risk Assessment Tool) calculator is available online for clinical use. Our Taiwanese Osteoporosis Clinical Treatment Guidelines suggests using the American high risk cut-points for…
- Trial name
- NCT01930656
- Where
- Taiwan
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Osteoporosis in Post-menopausal Women, Prevention
Development of a Wearable Device for Osteoporosis Prevention and Fracture Risk Reduction in Women
This project aims to determine the impact on bone health of: A lifestyle intervention promoting impact-based activities and physical activity for nine months. The same program enhanced with home-based strength training.
- Conditions
- Osteoporosis in Post-menopausal Women, Prevention, Exercise, Physical Activity
- Trial name
- Weapom (NCT06741956)
- Testing
- Weapom Lifestyle Intervention to measure bone impacts using a Fitbit Versa wearable device and the Weapom App.
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Seville
Schizophrenia
The Effect of a Community-based LAI-treated Management Model on the Violence Risk of Patients With Schizophrenia
This is a 12-month open-label randomized controlled study. Patients with schizophrenia and violence risk under the government supervision will be enrolled in the study.
- Trial name
- NCT03080194
- Testing
- paliperidone palmitate, control group
- Volunteers
- 150 people
- Sponsor
- Maosheng Fang
Diabetes
Intensive Case Diabetes Management (ICDM) to Prevent Readmission
The purpose of this study is to assess whether intensive case management interventions by a diabetes team, led by an endocrinologist and certified diabetes educator, can prevent <31 day readmission in previously identified high…
- Trial name
- NCT02230488
- Testing
- Intensive Diabetes Case Management
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine
Campylobacter Infections
Campylobacter Spp. Bone and Joint Infection: a Retrospective Cohort Study
Campylobacter bacteria, a Gram-negative bacillus commensal in the digestive tract of many animals and mainly responsible for human infections with digestive origins, has been little studied in the field of osteoarticular…
- Trial name
- Campylo-BJI (NCT06425250)
- Testing
- Management, progression and risk factors for failure of BJI caused by Campylobacter spp., Description of the evolution and risk factors for failure of osteoarticular infections caused by Campylobacter spp.
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Oropharynx Cancer
Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Oropharynx Cancer
This is a prospective, phase II, stratified single arm investigation for favorable prognosis in p16+ oropharynx cancer patients with either node negative or malignant neck adenopathy with lymphoscintigraphy mapping confined to…
- Trial name
- NCT05800574
- Testing
- Radiation therapy (5 days for 7 weeks), Radiation therapy (5 days for 6 weeks), Cisplatin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Fox Chase Cancer Center