Clinical trials: Management, Risk
Bladder Cancer
Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer
Disease recurrence and progression is a major issue in high risk non-muscle-invasive bladder cancer (NMIBC). The current study compares two adjuvant instillation therapies in the treatment of high risk NMIBC.
- Trial name
- FB10 (NCT03664869)
- Testing
- BCG instillation therapy, Sequential BCG and EMDA mitomycin C
- Where
- 7 sites in Finland
- Volunteers
- 300 people
- Sponsor
- Turku University Hospital
Endometrium Cancer
PET/CT in the Management of Patients With Early Stage Endometrial Cancer
Endometrial cancer (EC) is the most common gynecologic malignancy in the developed countries and is the fifth most common cancer among women worldwide.
- Trial name
- ENCA-1 (NCT03570866)
- Testing
- Positron emission tomography and computed tomography, Surgical treatment
- Volunteers
- 40 people
- Sponsor
- Università degli Studi dell'Insubria
Risk Reduction
Cultural Competency, Risk Management, and Patient Safety Internet-Based Curriculum for OB/GYN Resident Physicians
Additional educational training lectures were provided to healthcare workers. Outcome measure of cultural competency was completed to assess patient safety, risk management, and cultural competency of healthcare providers in an…
- Trial name
- PROM (NCT02355847)
- Testing
- Lectures
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Brett Worly, MD
Osteoporotic Fractures, Osteoporosis
Stop At One Stockholm (SAOS)- Secondary Fracture Prevention Through Active Patient Identification and Staff Education.
This is a study on the effects of education on secondary fracture prevention in primary health care centers (PHCC) and referral from hospitals to these PHCC of patients with recent fragility fractures.
- Conditions
- Osteoporotic Fractures, Osteoporosis, Osteoporosis Risk
- Trial name
- SAOS (NCT04565743)
- Testing
- Support on dentification and treatment of patients with high risk of osteoporotic fractures
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Helena Salminen
Cardiovascular Health, Self-management
MECA Clinical Intervention ( MECA Health360x)
The purpose of this research is to test whether a technology application(Health360x) that lets participants set goals for better health and track health can help participants reduce their heart disease risk.
- Trial name
- MECAH360x (NCT04791618)
- Testing
- Health360x plus health coach, Health360x only (High tech)
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Diabetes Mellitus, Schizophrenia
Diabetes Screening, Risk Management and Disease Management in a High-Risk Mental Health Population Part II
The purpose of this study is to learn more about the relationship between serious mental illness and the detection and management of diabetes and pre-diabetic conditions.
- Conditions
- Diabetes Mellitus, Schizophrenia, Psychotic Disorders
- Trial name
- NCT00377117
- Testing
- Management, Screening
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stroke, Ischemic
Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke
People living with the cognitive effects of stroke are at risk for recurrent stroke and further cognitive decline. Also problematic is that stroke risk clusters in families and biological family members of people who have…
- Trial name
- CHAMPS-TR (NCT06479174)
- Testing
- CHAMPS-TR
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Mask Ventilation, General Anesthesia
Prediction of Difficult Mask Ventilation Using 3D-Facescan and Machine Learning
The aim of this study is to prove feasibility and assess the diagnostic performance of a machine learning algorithm that relies on data from 3D-face scans with predefined motion-sequences and scenes (MASCAN algorithm), together…
- Trial name
- MASCAN (NCT05411406)
- Where
- Germany
- Volunteers
- 423 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Peripheral Arterial Disease
Multifactor Risk Reduction for Optimal Management of PAD
Patients with peripheral arterial disease (PAD) experience significant functional limitations due to ischemic symptoms (claudication) and are at high risk for CVD morbidity and mortality resulting from untreated cardiovascular…
- Trial name
- VIGOR2 (NCT00537225)
- Testing
- exercise
- Volunteers
- 300 people
- Sponsor
- Palo Alto Veterans Institute for Research
Arterial Hypertension
"Community-based, eHealth Supported Management of Cardiovascular Risk Factors by Lay Village Health Workers (ComBaCaL aHT TwiC 1 & ComBaCaL aHT TwiC 2)
ComBaCaL aHT TwiC 1 and aHT TwiC 2 are two cluster-randomized controlled trials that are identical in intervention, design and endpoints.
- Trial name
- NCT05684055
- Testing
- First-line antihypertensive single-pill combination (SPC), Standardized counselling and referral to the closest health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 1,354 people
- Sponsor
- University Hospital, Basel, Switzerland
High-risk Pregnancy, Pregnancy
AI-Powered CURAᵀᴹ Application for Identifying At-Risk Pregnancies in Obstetric Management
It is important to identify high pregnancies early through screening so that appropriate care and intervention may be instituted.
- Conditions
- High-risk Pregnancy, Pregnancy, Antenatal Health
- Trial name
- CURAte (NCT06974188)
- Testing
- AI-risk Stratification
- Where
- Singapore
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Cardiovascular Diseases, Hypertension
ICA-CHAMP: Indo-Central Asian Cardiovascular Health Assessment and Management Program
Research has shown that the presence of heart disease and stroke is higher in the Indo-Asian population compared to other ethno-cultural groups.
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia
- Trial name
- ICA-CHAMP (NCT00627159)
- Testing
- High risk assessment, Low to moderate risk
- Where
- 2 sites in Canada
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Performance and Safety of an Airway Management Device
Comparison of the BASKA Airway, a Novel Supraglottic Device, to the LMA Airway in Low Risk Female Patients
The investigators have performed a number of studies on novel airway devices, including an observational study on the performance of a new supraglottic airway named Baska mask.
- Trial name
- NCT01482650
- Testing
- supraglottic airway placement and use
- Where
- Ireland
- Volunteers
- 92 people
- Sponsor
- University College Hospital Galway
Preeclampsia Severe, Toxemia Of Pregnancy
LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention
Preeclampsia is a major cause of maternal and perinatal morbidity and mortality worldwide. Low-dose aspirin started in the first trimester reduces the risk of preeclampsia in high-risk women.
- Conditions
- Preeclampsia Severe, Toxemia Of Pregnancy, Preeclampsia, Pregnancy Complications
- Trial name
- preGO (NCT07361679)
- Testing
- Aspirin, Tinzaparin
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Alexandra Hospital, Athens, Greece
Ischemic Stroke
Clinical Registration Trial of Intracranial Stenting for Patients With Symptomatic Intracranial Artery Stenosis(CRTICAS)
This trial is an prospective, government-funded registration study that will observe the safety and effectiveness of intracranial stenting for preventing stroke during a mean follow-up of 12 months in patients with symptomatic…
- Trial name
- NCT01994161
- Testing
- intracranial stenting
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Xuanwu Hospital, Beijing
HIV, HIV Testing
A Reinforcement Intervention for Increasing HIV Testing Among At-Risk Women
African American and Latina women, as well as women living in poverty, are an identified health disparities population for HIV. Risks for HIV are compounded in this population when additional risk factors are present, including…
- Conditions
- HIV, HIV Testing, Women, Contingency Management
- Trial name
- NCT03768986
- Testing
- Standard referral for HIV testing, Online risk reduction training, Reinforcement
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- UConn Health
Endometrial Cancer, Endometrial Neoplasms
[SENTRY] Tailoring Postoperative Management Through Sentinel Lymph Node Biopsy in Low- and Intermediate-Risk Endometrial Cancer
While total hysterectomy without lymph node staging is standard for low- and intermediate-risk endometrial cancer, certain histopathologic factors can necessitate additional interventions.
- Conditions
- Endometrial Cancer, Endometrial Neoplasms, Endometrial Adenocarcinoma, Endometrial Cancer Stage I
- Trial name
- SENTRY (NCT04972682)
- Testing
- Laparoscopic total hysterectomy with bilateral salpingo-oophorectomy and sentinel lymph node biopsy
- Where
- Russia
- Volunteers
- 102 people
- Sponsor
- Moscow City Oncology Hospital No. 62
Bladder Neoplasms
Mycobacterial Cell Wall-DNA Complex in Treatment of BCG-refractory Patients With Non-muscle Invasive Bladder Cancer
The purpose of this study is to determine the efficacy and safety of intravesical Mycobacterial Cell Wall-DNA Complex (MCC) in patients with non-muscle invasive transitional cell carcinoma (papillary tumors and/or carcinoma in…
- Trial name
- NCT00406068
- Testing
- Mycobacterial cell wall-DNA complex
- Where
- 31 sites in United States, Canada
- Volunteers
- 129 people
- Sponsor
- Bioniche Life Sciences Inc.
Behavior, Risk
Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention Among Homeless Youth
The purpose of this study is to to determine the efficacy of the Nurse Case Management HIV (NCM4HIV) intervention on HIV prevention compared to usual care among Youth Experiencing Homelessness (YEH).
- Trial name
- NCT03910218
- Testing
- NCM4HIV, Usual Care
- Where
- United States
- Volunteers
- 474 people
- Sponsor
- The University of Texas Health Science Center, Houston
Prostate Cancer
The Metformin Active Surveillance Trial (MAST) Study
This study aims to see if metformin can delay the time to progression in men with low risk prostate cancer when compared to a placebo.
- Trial name
- MAST (NCT01864096)
- Testing
- Metformin
- Where
- 12 sites in Canada
- Volunteers
- 408 people
- Sponsor
- University Health Network, Toronto