Clinical trials: Management, Risk
Post-operative Complications, Surgical Site Infection
The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
The purpose of this study is to compare the post-surgical standard-of-care dressing to the Prevena™ Incision Management System in women undergoing Cesarean section surgery.
- Conditions
- Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
- Trial name
- NCT01450631
- Testing
- Prevena™ Incision Management System (PIMS), Standard-of-care Dressing
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- KCI USA, Inc
High-Risk Pregnancies
The Effect of Paint-by-Numbers Activity on Stress and Prenatal Attachment in High-Risk Pregnancies
Pregnancy, a physiological state, is defined both as a turning point and a developmental crisis . Pregnancy directly affects maternal and child health, and in cases of complications, it can lead to morbidity and mortality…
- Trial name
- NCT06955312
- Testing
- Experimental
- Volunteers
- 60 people
- Sponsor
- Erzurum Technical University
Pain
Preemptive Genotyping and Pain Management
The purpose of this study is to see if testing for genes related to pain and pain management before surgery affects how patients are treated for pain after surgery.
- Trial name
- NCT01813695
- Testing
- Preemptive genotyping in medical record, Genotyping not included in electronic medical record
- Where
- United States
- Volunteers
- 576 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Coronary Artery Disease
Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer
REDEEM-CAD is a prospective multi-centre study of CAD risk evaluation and management in cancer survivors 40-70 years with chemotherapy or radiotherapy >5 years ago.
- Trial name
- REDEEM-CAD (NCT05366153)
- Testing
- Coronary CT
- Where
- 2 sites in Australia
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Baker Heart and Diabetes Institute
Structured Interview, Narrative Assessment
Refinement of Suicide Risk Management Intervention
Participants will be randomly assigned to 1 of the 4 interventions using a sequential stratified randomization procedure. We will use sex (M, F) and history of suicide attempts (never, 1, and multiple) as our randomization…
- Conditions
- Structured Interview, Narrative Assessment, Safety Plan, Crisis Response Plan
- Trial name
- NCT04888845
- Testing
- Safety Plan, Crisis Response Plan, Structured interview
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Utah
Lumbar Pain Syndrome
Impact of a Multidisciplinary Rehabilitation Program Associated With the Doado Application in Lowback Pain Management
This study is aimed at patients consulting a physiotherapist for acute low-back pain at risk of becoming chronic. The goal of this study is to compare two types of rehabilitation programs for these patients, on their functional…
- Trial name
- REEDUCALGIE (NCT07061405)
- Testing
- Multidisciplinary management associated with mobile application Doado, Physiotherapy management alone associated with mobile application Doado
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Elsan
Acute Myeloid Leukaemia (AML), Myelodysplastic Syndrome (MDS)
Dose-escalation Study of Oral Administration of S 055746 in Patients With Acute Myeloid Leukaemia or Myelodysplastic Syndrome
The purpose of this study is to determine the safety profile and tolerability of S 055746 in patients with AML, and high or very high risk MDS, in terms of Dose-Limiting Toxicities (DLTs), Maximum Tolerated Dose (MTD) and…
- Trial name
- NCT02920541
- Testing
- S 055746
- Where
- 5 sites in Australia, France
- Volunteers
- 48 people
- Sponsor
- Institut de Recherches Internationales Servier
Obstructive Sleep Apnea Risk Management, Postoperative Complications
OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia
Obstructive sleep apnea (OSA) is a sleep-related respiratory dysfunction. The prevalence of OSA is increasing with the increasing rates of obesity and elderly population worldwide.
- Conditions
- Obstructive Sleep Apnea Risk Management, Postoperative Complications, Dental Caries Under General Anesthesia, Obstructive Sleep Apnea of Adult
- Trial name
- NCT06430957
- Testing
- The STOP-BANG questionnaire for determining OSA risk level., ASA recommended criteria for determining OSA risk level., Record of postoperative complications
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Kırıkkale University
Type 2 Diabetes
Characterization of Cardiovascular Risk Profile and Therapeutic Management in Patients With Type 2 Diabetes Mellitus in Italy
CardioMET is an observational, multicenter, real-life registry, intending to collect data on patients with Type 2 Diabetes Mellitus, attending internal medicine and cardiology outpatient clinics.
- Trial name
- CardioMET (NCT07375069)
- Testing
- data collection
- Where
- Italy
- Volunteers
- 3,000 people
- Sponsor
- Federico II University
Atherosclerotic Cardiovascular Diseases (ASCVD)
Prospective Assessment of Atherosclerotic Cardiovascular Disease (ASCVD) Risk
This study aims to conduct a 10-year follow-up to assess ASCVD risk in Pakistan among individuals aged 30 years and above without a known history of ASCVD.
- Trial name
- NCT06316453
- Testing
- Evaluating ASCVD risk over 10 and 30 year and lifetime
- Where
- Pakistan
- Volunteers
- 3,513 people, healthy volunteers welcome
- Sponsor
- Advanced Education & Research Center
Gastro Intestinal Bleeding
Management of Digestive Haemorrhaging In CHRU of Brest During 2009 and 2014
Gastro intestinal (GI) bleeding is relatively frequent and may lead to intensive care unit admission. Although a restrictive strategy for red blood cell transfusion is supported by a large randomized controlled trial literature…
- Trial name
- HDréa (NCT03379285)
- Where
- France
- Volunteers
- 272 people
- Sponsor
- University Hospital, Brest
Myocardial Infarction
Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk.
The primary purpose of this study is to determine if there are significant differences with respect to baseline between those randomized to CGo and standard-of-care versus standard-of-care alone after completing 12-weeks of…
- Trial name
- CalmiGo (NCT04521699)
- Testing
- CalmioGO Stress management device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Coronary Heart Disease (CHD)
Effect of eHealth Cardiac Rehabilitation Incorporating Mindfulness for Patients With Coronary Heart Disease
People with coronary heart disease (CHD) often feel more stressed, which can increase the risk of having another heart problem. Cardiac rehabilitation (CR) is a common treatment for those with CHD, focusing on changing lifestyles…
- Trial name
- eCR (NCT07109752)
- Testing
- eHealth cardiac rehabilitation
- Where
- Hong Kong
- Volunteers
- 146 people
- Sponsor
- Tung Wah College
Acute Stroke
A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients
Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management.
- Trial name
- NCT05454397
- Testing
- Observational study, no intervention
- Where
- 34 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Heart Disease
SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX®-Trial).
The aim of the investigators' research program is to investigate the effects of perioperative high dose selenium supplementation in high-risk cardiac surgical patients undergoing complicated open heart surgery.
- Trial name
- SUSTAINCSX (NCT02002247)
- Testing
- sodium selenite
- Where
- 23 sites in Canada, Germany
- Volunteers
- 1,400 people
- Sponsor
- Daren K. Heyland
Hypertension
Epidemiological Study In Hypertensive Patients: Assessment Of Risk Factors Prevalence And Of Patients' Management
To assess the pattern of hypertension in the population in terms of presence of additional risk factors (ARF) and cardiovascular risk stratification.
- Trial name
- NCT00709787
- Testing
- Usual Care
- Where
- 2 sites in Croatia, Czechia
- Volunteers
- 899 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Atherosclerotic Cardiovascular Disease, Atherosclerotic Cardiovascular Disease Risk Equivelents
Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support
The purpose of this study was to evaluate the implementation of inclisiran in a regional primary care setting in the UK Inclisiran, also known as KJX839, is a medication made to reduce the level of "bad" cholesterol…
- Conditions
- Atherosclerotic Cardiovascular Disease, Atherosclerotic Cardiovascular Disease Risk Equivelents, Elevated Low Density Lipoprotein Cholesterol
- Trial name
- SPIRIT (NCT04807400)
- Testing
- Inclisiran, Behavioural Support, Background lipid lowering therapy
- Where
- 17 sites in United Kingdom
- Volunteers
- 892 people
- Sponsor
- Novartis Pharmaceuticals
Nasal Obstruction, Nasopharyngeal Obstruction
Administration of Dexamethasone in PONV Prophylaxis in Children Undergoing Adenotomy
Adenotomy, together with tonsillectomy, belongs among the most frequently performed surgical procedures in paediatric patients. These surgical procedures are associated with the second highest incidence of post-operative nausea…
- Conditions
- Nasal Obstruction, Nasopharyngeal Obstruction, Snoring, Apnea, Obstructive
- Trial name
- NCT03398044
- Testing
- Dexamethasone
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians
Cardiovascular disease (CVD) is a serious health concern for American Indians, but there have been few behaviorally based programs to lessen CVD risk among this population.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension, Obesity
- Trial name
- NCT00608387
- Testing
- Chronic disease management Web-based software
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Black Hills Center for American Indian Health
Massive Transfusion, Nomogram Model
A Nomogram Predicting the Risk of High-dose Transfusion in Non-cardiac Surgery
This retrospective study was designed to develop a preoperative nomogram, validated both internally and externally, to supply an individual and precise tool for predicting the probability that patients will require perioperative…
- Trial name
- NCT06701747
- Where
- China
- Volunteers
- 11,197 people
- Sponsor
- West China Hospital