Clinical trials: Mandible
Partial Denture
A Study to Determine the Efficacy of a Denture Adhesive to Seal Out Food Particles From Under the Mandibular Partial Denture
The objective of this study is to evaluate the effectiveness of two denture adhesives at keeping food particles (seeds) from becoming trapped underneath partial denture(s).
- Trial name
- NCT05908890
- Testing
- Experimental Denture Adhesive, Fixodent True Feel Denture Adhesive
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Aging, Healthy
The Evaluation of Efficacy and Safety of Stylage® XL Lidocaïne for the Restoration and/or Augmentation of Facial Volume
Stylage® XL Lidocaïne is a CE-marketed hyaluronic acid gel indicated for the restoration or augmentation of facial volume by injection into the deep dermis or subcutaneously.
- Trial name
- BeautyVolume (NCT04166292)
- Testing
- Stylage® XL Lidocaïne
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Mandibular Diseases, SSM
Virtual Anatomical Reconstruction of Mandibular Bone Defects Using a Statistical Shape Model
Hundred already taken CT-scans (50 male and 50 female) will be anonymized. These scans will be segmented and implemented into a statistical shape model that will be used to predict missing hard tissue of a mandible based on the…
- Trial name
- NCT04475237
- Testing
- CT-scan evaluation and segmentation
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- CADskills
Partial Edentulism, Complete Edentulism
Immediate Function of NobelSpeedy Shorty and Brånemark System® Mk III Shorty Implants in Daily Use
The aim of this study was to evaluate the 7 mm long implants NobelSpeedy Shorty and Brånemark System Mk III Shorty: by determining the marginal bone remodeling, implant survival rate, soft tissue health and maintenance.
- Trial name
- NCT02180230
- Testing
- Shorty implants
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Horizontal Bone Augmentation
A 1-year Clinical Investigation on the the CREOS™ XENOGAIN Bone Graft SUBSTITUTE
This clinical investigation is a prospective, multi-centre study to evaluate bone gain after horizontal augmentation using creos xenogain bone graft substitute.
- Trial name
- NCT03028922
- Testing
- creos xenogain
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1940
The primary aim of this study is to investigate if AZD1940 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00659490
- Testing
- AZD1940, Naproxen
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Acne Vulgaris
Effectiveness and Tolerance of Effaclar Serum in Women With Mandibular Acne
The role of "dermocosmetics" in acne management is increasingly important, as many patients and even physicians now resort to them as first-line management in mild-to-moderate acne.
- Trial name
- NCT05457621
- Testing
- Effaclar serum
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Edentulous or Failing Dentition Mandible
The TREFOIL Concept 5 Year Clinical Investigation
Prospective, single cohort, multi-center study evaluating the TREFOIL concept for the treatment of edentulous or patients with failing mandibular dentition over 5 years. 90 patients (15 per centre) will be included.
- Trial name
- NCT02940353
- Testing
- TREFOIL concept
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Edentulous
All-On-4® Treatment Concept
Indication : edentulous patients To evaluate and compare the marginal bone level change around tilted and straight NobelActive implants placed in healed sites with All-on-4-treatment concept after immediate function supporting…
- Trial name
- NCT02186912
- Testing
- Nobel Active, Nobel Procera IBO
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Edentulous
A Clinical Evaluation of NobelProcera Implant Bar Overdenture
AN OPEN 5-YEAR PROSPECTIVE, CLINICAL MULTI-CENTER STUDY on NobelProcera Implant Bar Titanium with Locator attachment and related Overdenture on 4 NobelReplace implants with conical connection (CC) in the mandible/maxilla.
- Trial name
- NCT01720420
- Testing
- NobelReplace CC, NobelProcera Implant Bar
- Where
- 7 sites in Germany, Italy
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Edentulous Jaw
Mandibular Full-arch Rehabilitation With Internal Hexagonal and Conical Connection Implants
Nuvo Tapered IF (internal hexagonal connection) and CF (conical connextion) Implants were designed for the the oral functional rehabilitation using dental implants, allowing for treatment of patients with different bone…
- Trial name
- NCT05082038
- Testing
- Mandibular partial rehabilitation with IF Tapared implants, Mandibular partial rehabilitation with CF Tapared implants
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Neodent
Temporomandibular Disorder, Motor Imagery
Assessing Motor Imagery Ability of Tongue and Mouth in Subjects With and With no Temporomandibular Disorders
Temporomandibular disorder (TMD) is the symptomatic expression of a muscular or an articular impairment at the manducatory tract. TMD affects between 30 to 65% of the population with a higher prevalence for young women.
- Trial name
- TMIQ (NCT04102306)
- Testing
- reliability and validity construct of the TMIQ
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Cabinet de Kinesitherapie SCM Saint-Alexandre
Partial Edentulism, Tooth Disease
TM vs TSV Implants Loaded Early vs Conventional in Anterior and Posterior Areas
Randomized-controlled, multicenter study of Trabecular Metal (TM) and Tapered Screw-Vent (TSV) dental implants loaded early in maxillary and mandibular sites.
- Trial name
- TMEL (NCT02158377)
- Testing
- Trabecular metal dental implants (TM), Tapered screw-vent implants (TSV)
- Where
- 3 sites in Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ZimVie
TMJ Disc Disorder, TMJ Pain
MDR-JuggerKnot Mini Soft Anchor in Maxillofacial TMJ
The objective of this retrospective consecutive series PMCF study is to collect data confirming safety, performance and clinical benefits of the JuggerKnot Mini Soft Anchor (implant and instrumentation) when used for soft tissue…
- Conditions
- TMJ Disc Disorder, TMJ Pain, TMJ Sounds on Opening/Closing the Jaw, TMJ Disease
- Trial name
- NCT04033692
- Testing
- JuggerKnot Mini Soft Anchor
- Volunteers
- healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Dental Research, Orthodontics
Treatment of the Mandibular Dental Crowding With and Without Corticotomy Surgery
The use of corticotomy surgery in addition to orthodontic standard treatment could accelerate the treatment. Corticotomy involves vertical interdental incisions of the gingiva and the bone with a very low thickness.
- Conditions
- Dental Research, Orthodontics, Surgery, Oral, Maxillofacial Surgery
- Trial name
- CORTICO (NCT03967002)
- Testing
- Test group with corticotomy surgery
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ardentis Cliniques Dentaires
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386
The primary aim of this study is to investigate if AZD1386 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00672646
- Testing
- AZD1386, Naproxen
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Surgery--Complications, Molar, Third
Probiotic Intervention After Surgical Removal of Mandibular Third Molars
Single-center, double-blind, randomized trial of probiotics L. plantarum KABP-051 (CECT7481) and L. brevis KABP-052 (CECT7480) taken twice daily for 7 days after surgical removal of both mandibular 3rd molars.
- Trial name
- NCT04203771
- Testing
- Probiotic AB-DENTALAC, Surgical removal of mandibular third molars at baseline, Ibuprofen
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Orofacial Myofunctional Disorders, Myo Munchee
Trial to Compare the Effects of Myo Munchee Therapy and Oral Motor Therapy (OMT) in Pediatric Patients to Treat Maxillary Deficiency and Orofacial Myofunctional Dysfunction (OMD).
Multi-center, 6-month, randomized, and controlled trial to compare the effects of Myo Munchee therapy and Oral Motor Therapy (OMT) in pediatric patients (aged 3-5 years) to treat maxillary deficiency and orofacial myofunctional…
- Conditions
- Orofacial Myofunctional Disorders, Myo Munchee, Oral Motor Therapy, Maxillary Deficiency
- Trial name
- NCT07088055
- Testing
- Chewing device only, Myo Munchee and Oral Motor Therapy Treatment, Oral Motor Therapy Treatment Arm
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Myo Munchee (Operations) Pty Ltd
Deficiency of Alveolar Ridge (Disorder), Alveolar Bone Grafting
Safety and Efficacy Evaluation of the Ivory Dentin Graft Device (IvoryGraft) - Long Term Follow-Up
long-term safety and performance of Ivory Dentin Graft. Ivory Dentin Graft is at least as good as the competitor treatment group (OsteoBiol Gen-Os) for alveolar ridge preservation following tooth extraction.
- Conditions
- Deficiency of Alveolar Ridge (Disorder), Alveolar Bone Grafting, Mandibular Prosthesis User
- Trial name
- NCT04868825
- Testing
- Ivory Dentin Graft, OsteoBiol Gen-Os
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Ivory Graft Ltd.
Tooth Loss
Performance Evaluation of FullCeram Implants in Single Tooth Gaps
Straumann Monotype FullCeram implants serve as a suitable alternative for implant therapy especially in the aesthetic zone The survival rate of Straumann Ceramic implants should be at least 85% (max 6 implant losses out of 40…
- Trial name
- NCT02163395
- Testing
- FullCeram implant
- Where
- 3 sites in Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG