Clinical trials: Mandibular Dysfunction
Temporomandibular Joint Disorders
Nd-YAG Laser Versus Epidermal Growth Factor For Myogenic Tempromandibular Disorder.
A clinical trial comparing the potential effect of 2 different modalities (Nd-YAG Laser Versus Epidermal growth factor injection) on pain reduction in patients suffering from myogenic tempromandibular disorder.
- Trial name
- NCT06044974
- Testing
- Nd-YAG Fotona, Epidermal Growth Factor
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Temporomandibular Joint Disorders
Comparison of Psychological and Pharmacological Treatments for Pain Due to Temporomandibular Joint Disorder (TMD)
The purpose of this study is to determine whether the combination of cognitive-behavioral treatment and nortriptyline are more effective than each treatment alone in reducing the pain and disability associated with TMD.
- Trial name
- NCT00066937
- Testing
- Nortriptyline Oral Capsule, Benztropine Oral Product, CBT
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Johns Hopkins University
Temporomandibular Joint Disorders, Chronic Pain
Integrating Behavioral Therapy in the Management of Temporomandibular Disorders: A Comprehensive Evaluation Using DC/TMD Axis II Criteria
This study evaluates the efficacy of behavioral therapy, including Cognitive Behavioral Therapy (CBT), relaxation techniques, and biofeedback, in managing Temporomandibular Disorders (TMD).
- Conditions
- Temporomandibular Joint Disorders, Chronic Pain, Anxiety Disorders
- Trial name
- NCT06774196
- Testing
- Behavioral Therapy Group, Standard Care Group
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Khalid University
Temporomandibular Joint Pain
TMD Pulsed Radiofrequency
PRF of the masticatory muscles (masseter, temporalis, medial and lateral pterygoid muscle) can improve pain intensity and functional recovery of the jaw in patients with extra-articular TMD.
- Trial name
- NCT03848169
- Testing
- Radiofrequency
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
TMJ Disc Disorder, TMJ Pain
RCT of a Temporomandibular Joint Distraction Device for Patients With Articular Disorders Diagnosis
Articular Disc Displacements are the most common TMJ arthropathy and the articular distraction technique is one of the most common therapeutic resources.
- Conditions
- TMJ Disc Disorder, TMJ Pain, TMJ Sounds on Opening/Closing the Jaw, TMJ - Injury of Meniscus of Temporomandibular Joint
- Trial name
- TMJ_Dist (NCT03737305)
- Testing
- TMJ Condilar Distraction Device, Conventional Physical Therapy
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Fonseca, Julio
Bruxism, Posture
Determining the Relationship Between Posture, Muscle Stiffness, Pain, and Jaw Functionality in Individuals With Bruxism
Bruxism is a repetitive jaw-muscle activity characterized by teeth clenching and/or grinding, often associated with temporomandibular joint dysfunction, pain, and impaired jaw function.
- Conditions
- Bruxism, Posture, Sleep Quality, Pain Assessment
- Trial name
- Bruxism (NCT07560670)
- Testing
- Bruxism Assessment Form, Clinical Examination, Patient Evaluation Form
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Temporomandibular Joint Disorders
The Effect of Opioid-Free Anesthesia in TMJ Surgery
This study aims is to evaluate the effect of opioid free total intravenous anesthesia on postoperative quality of recovery in patients undergoing oral and maxillofacial surgery (OMF) temporomandibular joint (TMJ) surgery.
- Trial name
- NCT04724759
- Testing
- Dexmedetomidine / Ketamine / Lidocaine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Temporomandibular Disorders, Orofacial Pain
Genetic Polymorphisms and Their Association With Temporomandibular Disorders
Temporomandibular disorders (TMD) are the most common orofacial pain disorders of non-dental origin with the prevalence of 6.1-10.2%, and incidence of 3.9%.
- Trial name
- GenPolTMD (NCT04694274)
- Testing
- stabilization splint, physical therapy
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croatian Science Foundation
TMJ Disorder, Myofacial Pain
Comparison of Cannabinoids to Placebo in Management of TMJ Pain and Myofascial Pain in the TMJ Region
The aim of this study is to determine whether the cannabinoids taken orally in the form of cannabidiol (CBD oil-a major non-psychoactive component of marijuana) vs placebo (hemp oil) will provide pain relief and improved jaw…
- Conditions
- TMJ Disorder, Myofacial Pain, TMD
- Trial name
- NCT04298554
- Testing
- CBD Oil, Hemp Oil
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Weill Medical College of Cornell University
Temporomandibular Disorder, Depression
Determination of Chronic Pain, Anxiety, Depression and Perceived Stress in Adults With Temporomandibular Disorders
The aim of the study was to asses levels and relationship of chronic pain, anxiety, depression and perceived stress in TMD patients .
- Conditions
- Temporomandibular Disorder, Depression, Anxiety, Pain
- Trial name
- NCT05183503
- Testing
- DC/TMD examination
- Where
- Poland
- Volunteers
- 219 people
- Sponsor
- Wroclaw Medical University
Temporomandibular Disorders (TMDs), Splint Therapy
Development and Validation of a Temporomandibular Disorders (TMDs) Adherence Questionnaire
The goal of this observational study is to assess patient adherence to splint therapy and behavioral counseling among individuals diagnosed with TMDs.
- Conditions
- Temporomandibular Disorders (TMDs), Splint Therapy, Behavioral Counseling, Treatment Adherence and Compliance
- Trial name
- TMDs (NCT07045441)
- Testing
- Conservative Management for TMD
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Soaad Tolba Mohammed Tolba Badawi
Head Pain, TMJ Disorder
Masticatory Muscles Electromyography in Post-pubertal Females With Forward Head Posture and Temporomandibular Disorders
The aim of this study was to evaluate masticatory muscle electrical activity in post-pubertal females with forward head posture (FHP) and temporomandibular disorders (TMD) as well as in post-pubertal females with neutral head…
- Trial name
- NCT05712655
- Testing
- Measurement of bilateral electromyographic activity of Masseter and Anterior Temporalis muscles.
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Diseases of the Temporomandibular Joint
Study of Temporomandibular Joint Dysfunction
Given the frequency of temporomandibular joint (TMJ) dysfunction and the variations in its expression, this project intends to initiate a process of objective evaluation of mandible function and its impairment due to different…
- Trial name
- CinématiqueATM (NCT03305315)
- Testing
- Measurements of jaw movement, Measurement of natural electrical activity of facial muscles
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Temporomandibular Disorder (TMD)
Turkish Version of Helkimo Clinical Dysfunction Index
This study aimed to translate the Helkimo Clinical Dysfunction Index (HCDI) into Turkish and to test its validity and reliability as an outcome measurement method in individuals with temporomandibular dysfunction (TMD).
- Trial name
- NCT07371143
- Testing
- Turkish Version of Helkimo Clinical Dysfunction Index and Accompanying Scales
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Sevgi Medical Center
TMJ Disorder, Mandibular Deficiency
Virtual Planning of Total TMJ Replacement
Virtual Planning of Total TMJ Replacement
- Conditions
- TMJ Disorder, Mandibular Deficiency, TMJ Ankylosis
- Trial name
- TJR (NCT07643259)
- Testing
- Custom made TMJ
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Stroke, Mastication Disorder
Expiratory Muscle Training in Stroke
Stroke affects the vital activities of daily living such as breathing and swallowing. After stroke excursion of the diaphragm reduces about 50%, and also the maximum expiratory pressure of the individual 50% or higher.
- Conditions
- Stroke, Mastication Disorder, Temporomandibular Disorders, Dysphagia
- Trial name
- NCT04569968
- Testing
- Expiratory muscle training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Abant Izzet Baysal University
Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
Arthrocentesis Versus Botulinum Toxin Injection in Patients With Temporomandibular Joint Disorders: A Randomized Controlled Trial
The goal of this clinical trial is to learn if arthrocentesis works as well as botulinum toxin (Botox) injection to treat pain and jaw dysfunction in adults with temporomandibular joint (TMJ) disorders.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Facial Pain
- Trial name
- RCT (NCT07736521)
- Testing
- Arthrocentesis, Botulinum Toxin-A
- Volunteers
- 66 people
- Sponsor
- Mudher MB Alsunbuli
Myofascial Pain Syndrome, Temporomandibular Disorder
The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
Participants with chronic orofacial pain caused by masticatory and neck muscles will be distributed in two groups, both followed with the same occlusal and self-care treatment.
- Trial name
- TrP-TMD (NCT03619889)
- Testing
- Manual pressure release technique on trigger points.
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad Complutense de Madrid
Temporomandibular Joint Disorders
Validation of a Standardized Tool for Evaluation Function of Patients With TMD
Temporo-Mandibular Disorders (TMD) are the reason for consultation on more common in maxillofacial. However, there is no consensus on their care.
- Trial name
- DTM-SCORE (NCT03871608)
- Testing
- Examination of functional etiologies on DTM Disorders, Assessment of symptoms on DTM Disorders
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Temporomandibular Joint Disorders, TMD
Efficacy and Safety of HA35 Gel Nighttime Occlusive Application for TMD Pain
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of nighttime occlusive application of 10% high-concentration 35 kDa hyaluronan (HA35) gel in subjects with temporomandibular…
- Conditions
- Temporomandibular Joint Disorders, TMD, Temporomandibular Joint Pain, Jaw Muscle Over-Tension
- Trial name
- HA35-TMJ (NCT07584642)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC