Clinical trials: Mandibular Resection
Impact Molar
Clinical and Radiographic Evaluation of Local Application of Melatonin on Postoperative Outcomes After Surgical Removal of Impacted Mandibular Third Molar
Clinical and Radiographic Evaluation of Local Application of Melatonin on Postoperative Outcomes after Surgical Removal of Impacted Mandibular Third Molar: A Randomized Controlled Study
- Trial name
- NCT07374536
- Testing
- Control, Melatonin gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Otorhinolaryngologic Diseases
Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis
This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a latissimus dorsi or pectoral flap, to…
- Trial name
- NCT00213837
- Testing
- Mandibular prosthesis made of a new highly biointegratable material
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Strasbourg, France
Impacted Third Molar, Postoperative Pain
Kynurenic Acid and Serotonin as Perioperative Neuroinflammatory Biomarkers in Sequential Third Molar Surgery
A prospective cohort of 40 consecutive patients with bilateral impacted mandibular third molars underwent two sequential surgical extractions separated by a two-week interval.
- Conditions
- Impacted Third Molar, Postoperative Pain, Neuroinflammation, Anxiety
- Trial name
- KYNA-3M (NCT07644065)
- Testing
- Ibuprofen, Ibuprofen + Gabapentin
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Surgical Flaps, Oral Surgical Procedures
Oral Flap Outline and Local Blood Supply After Surgical Removal of Lower Third Molar Teeth
Wisdom teeth in the lower jaw are frequently buried in bone and must be taken out surgically. To reach the tooth, the surgeon lifts the gum away from the bone as a flap, and the shape of that flap is left to the surgeon's…
- Conditions
- Surgical Flaps, Oral Surgical Procedures, Regional Blood Flow, Tooth, Impacted
- Trial name
- NCT07758192
- Testing
- Sulcular flap elevation for wisdom tooth removal, Three-cornered flap elevation for wisdom tooth removal
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Betül Taş Özyurtseven
Odontogenic Tumors, Odontoma
Computer Guided Buccal Cortical Plate Separation for Removal of Calcified Benign Odontogenic Tumors Affecting Mandibular Angle Region
Computer guided buccal cortical plate separation was performed for ten patients using patient specific osteotomy locating guides and pre-bent plates.
- Trial name
- NCT05329974
- Testing
- Computer guided buccal cortical plate separation
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wisdom Tooth Removal, Dental Anesthesia
Effect of Subperiosteal Ropivacaine After Third Molar Extraction
This study examined whether an additional injection of the long-acting local anesthetic ropivacaine at the surgical site could reduce pain and improve recovery after removal of lower wisdom teeth.
- Conditions
- Wisdom Tooth Removal, Dental Anesthesia, Ropivacaine
- Trial name
- NCT07844824
- Testing
- Ropivacaine 0.75%, Saline (0.9% NaCl)
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Mandibular Tumors
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
The purpose of this study is to compare Aesthetic results and operation time of free fibular flap with and without CAD/CAM customized osteotomy guide for reconstruction of mandibular defects.
- Trial name
- NCT03757273
- Testing
- FFF with CAD/CAM customized cutting guide, FFF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Impacted Third Molar Tooth
Effect of Honey and Dexamethason on Extraction Healing
Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated
- Trial name
- NCT04848259
- Testing
- Normal saline, Dexamethasone, Honey
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pain, Postoperative
Postoperative Course Following Wisdom Tooth Surgery
The purpose of this study is to determine how quality of life changes after surgical removal of wisdom teeth
- Trial name
- NCT00921479
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Ullevaal University Hospital
Impacted Third Molar Tooth
The Effect of Melatonin Application Following Removal of Impacted Third Molar
In the present study, the main hypothesis hypothesizes that the local application of melatonin in the post-extraction socket produces favorable differences in the immediate postoperative period, as anti-inflammatory, analgesic…
- Trial name
- NCT04424875
- Testing
- 3 mg melatonin
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Fayoum University
Wisdom Teeth
Evaluation of the Effect of Circadian Rhythm of Adrenal Glucocorticoids After Third Molar Extraction
This study aimed to investigate the effects of wisdom tooth surgery performed at different times of the day on pain, swelling and trismus based on changes in the circadian rhythm in the adrenal glands in patients aged between…
- Trial name
- NCT06610383
- Testing
- Surgical extraction of wisdom teeth in the morning, Surgical extraction of wisdom teeth in the afternoon
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Head and Neck Cancer, Oral Cancer
Improved Implant for Reconstruction Purposes After Mandibular Resection
Study design: A single center non-randomized, prospective clinical feasibility study. Study population: Study population is composed of 10 patients ineligible for a free-flap bone reconstruction.
- Trial name
- RifRam (NCT05153733)
- Testing
- RIFRAM implant
- Where
- Netherlands
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
Surgical Wound, Healed, Post Operative Pain
Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars
Brief summary The goal of this study is to compare the effects of advanced platelet rich fibrin and enamel matrix derivative placed in the extraction alveoli of patients who had surgical removal of mandibular wisdom teeth.
- Trial name
- NCT06190015
- Testing
- Advanced platelet rich fibrin (APRF) clots, Enamel matrix derivative (EMD) group
- Where
- Serbia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
PRF
The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin)
Objectives: This study aims to evaluate the effects of A-PRF+ on postoperative pain, swelling, and trismus after surgical removal of impacted mandibular third molars.
- Trial name
- A-PRF+ (NCT05824793)
- Testing
- A-PRF+
- Where
- Vietnam
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery
Impacted mandibular third molars are among the most commonly encountered conditions in oral and maxillofacial surgery. Surgical removal of these teeth is frequently associated with postoperative complications such as pain, facial…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Edema Face
- Trial name
- PRF-M3M (NCT07672951)
- Testing
- Platelet-rich fibrin (PRF), Sterile Absorbable Gelatin Sponge
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- PAEC General Hospital, Islamabad
Mandibular Injuries
EVPOME Versus AlloDerm in Subjects Reconstructed With Large Defect Mandibular Resection
The purpose of this study is to compare the safety and effectiveness of performing oral reconstructive surgeries using either AlloDerm, a product commonly used for this purpose, or AlloDerm that has been overlaid with the…
- Trial name
- NCT01834339
- Testing
- AlloDerm, EVPOME
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stephen E. Feinberg
Virtual Surgical Planning, Benign Neoplasm
Virtual Surgical Planning in Mandibular Segmental Resection
Purpose: Odontogenic tumors, predominantly affecting the mandibular region, pose significant challenges in terms of treatment planning, particularly when requiring segmental mandibular resection.
- Conditions
- Virtual Surgical Planning, Benign Neoplasm, Mandible
- Trial name
- NCT06174532
- Testing
- Traditional Medthod, Virtual surgical planning
- Where
- Vietnam
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Tooth, Impacted
Effect of Hyaluronic Acid on Tissue Healing After Removal of Impacted Mandibular Third Molars (LM3)
Hyaluronic acid (HY) is used in dentistry to improve wound healing after oral and periodontal surgical interventions. After the application of HY, a positive effect on the wound healing of extraction sockets and periodontal…
- Trial name
- NCT04869306
- Testing
- Hyaluronic acid gel, Hyaluronic acid gel + carrier
- Where
- Austria
- Volunteers
- 102 people
- Sponsor
- Medical University of Vienna
Impacted Third Molar Tooth
Computer Guided Versus Conventional Surgical Removal of Deeply Impacted Mandibular Third Molar With Preservation of External Oblique Ridge
in patent have deeply impacted lower third molar ,dose computer guided enhance surgical outcome versus conventional surgical remove of wisdom teeth
- Trial name
- NCT03447067
- Testing
- computer guided surgical, Conventional surgery, CBCT
- Volunteers
- 18 people
- Sponsor
- Alaadden Mahmoud Abu Al Enein
Mastication Disorder
Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar
The purpose of this study is to determine the influence of platelet rich fibrin to reduction of periodontal problems after surgical removal of third molar.
- Trial name
- NCT01583491
- Testing
- autologous platlet rich fibrin, one side in control group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Majid Eshghpour