Clinical trials: Manipulation, Spinal
Neck Pain
Neuroendocrine Changes in Cervical Spinal Manipulation and Mobilization Non-specific Mechanical Neck Pain
The aim for this graduate student research project is to determine if cervical spinal mobilization releases similar neuropeptides and endogenous hormones as compared to cervical spinal manipulation and a control group.
- Trial name
- NCT04911608
- Testing
- cervical spinal manipulation, cervical spinal mobilization
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Mechanical Low Back Pain
Z-Joint Changes in Low Back Pain Following Adjusting
The purpose of this continuation project is to use MRI to evaluate gapping of the zygapophysial (Z) joints following side-posture positioning and side-posture spinal adjusting in subjects with acute low back pain.
- Trial name
- NCT00284063
- Testing
- Low back adjustment and MRI, MRI
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- National University of Health Sciences
Chronic Low-back Pain
The Impact of Positive, Neutral and Negative Expectation Speech on Manipulative Therapy Effects
The objective of this study will be to identify the short-term impact of positive, neutral, or negative speech on pain intensity (primary outcome).
- Trial name
- NCT05996991
- Testing
- Positive expectation speech regarding spinal manipulative therapy, Neutral expectation speech regarding spinal manipulative therapy, Negative expectation speech regarding spinal manipulative therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Low Back Pain
Trunk Motor Control Performance Before and After Spinal Manipulation Treatment
The overall goal of this project is to develop sensitive and objective clinical research tools for the assessment of trunk motor control.
- Trial name
- TMCSMT (NCT02261246)
- Testing
- Spinal manipulation treatment
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Low Back Pain
Neuroscience Education and Spinal Manipulation on Health Locus of Control in Low Back Pain
The purpose of this study is to evaluate the effects of combining Pain Neuroscience Education (PNE) with spinal manipulation for individuals suffering from chronic low back pain.
- Trial name
- LHC-LBP (NCT07639216)
- Testing
- Pain Neuroscience Education (PNE), Spinal Manipulation (SM)
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Centro Universitário Augusto Motta
Low Back Pain, Nutrition Poor
Nutrient Nutritional Advise for Low Back Pain Patients Seeking Chiropractic Care
The nutritional intervention will reduce LBP and cause 10% weight loss.
- Trial name
- NCT04134013
- Testing
- Combination: Nutrition AND Chiropractic Adjustment, Chiropractic Adjustment: Spinal Manipulation Therapy
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Parker University
Patient Safety, Manipulation, Spinal
(MIST1)-Part 1: Assessment & Feasibility of Post-Symptoms Evaluation
To increase patient safety culture in spinal manipulation therapy (SMT) this study will assess the ability to implement an active surveillance reporting system for a chiropractic teaching clinic and determining preliminary…
- Trial name
- MIST1 (NCT03412097)
- Testing
- active surveillance
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Parker University
Low Back Pain
Study of the Efficacy of Manual Therapy for a Subgroup of Acute Non-specific Low Back Pain
The purpose of this study is: To validate or not the interest of the classification using the pragmatic application of clinical predictive rule for low back pain to identify patients with good prognosis following a brief spinal…
- Trial name
- NCT01801553
- Testing
- Spinal manipulation, Usual medical care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
Low Back Pain
PRoGReSS-PS: Patient Response to GRraded Sensory Stimulation: A Pilot Study
The Patient Response to Graded Sensory Stimulation-Pilot Study (PRoGReSS-PS) will measure back pain perceptions in participants who receive either chiropractic treatment or foot massage.
- Trial name
- PRoGReSS-PS (NCT01842737)
- Testing
- Spinal treatment, Massage
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Palmer College of Chiropractic
Fibromyalgia
Effectiveness of Spinal Manipulation in Fibromyalgia
The aim of this study is to evaluate whether spinal manipulation, which is a potential treatment method for musculoskeletal pain, has an additional contribution in patients with fibromyalgia receiving standard pharmacological…
- Trial name
- NCT04673058
- Testing
- Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Spinal Cord Injuries
Osteopathic Manipulative Treatments and Neurogenic Bowel Dysfunction in Patients With Spinal Cord Injuries.
Studies based on the relationship between Osteopathic Manipulative Treatment (OMT) and the gastrointestinal system have been conducted in patients with constipation with Irritable Bowel Syndrome (IBS), and in children with…
- Trial name
- NCT04367571
- Testing
- Osteopathic Manipulative treatment (OMT)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Low Back Pain
Predicting Patients' Response to Spinal Manipulation
The purpose of this study is to compare the clinical effectiveness of two types of chiropractic spinal manipulation to conservative medical care for patients at least 55 years old with sub-acute or chronic LBP.
- Trial name
- NCT00285649
- Testing
- HVLA-SM, LVVA-SM, Usual Medical Care
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Palmer College of Chiropractic
Manual Therapies
Spinal Manipulation and Neuromuscular Performance on Amateur Cyclists
The present study aims to assess the effects of spinal manipulation therapy on neuromuscular performance.
- Trial name
- NCT03913546
- Testing
- Spinal manipulative therapy
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alcala
Lumbar Disc Herniation
Brain Connectomic Mechanisms of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
Low back and leg pain caused by lumbar disc herniation (LDH) is common. Lever positioning manipulation (LPM) is a spinal manual therapy used to relieve this pain, but how it affects the brain is unclear.
- Trial name
- NCT07728149
- Testing
- Active Lever Positioning Manipulation
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Recurrent Low Back Pain
B Vitamin Supplementation to Chiropractic Management of Chronic LBP: Pilot Clinical Trial (VCLBP)
The purpose of this investigation is to assess the effects of a combination of B vitamins (B6 [pyridoxine],, B9 [folate], and B12 [cyanocobalamin] upon the efficacy and duration of spinal manipulation in its treatment of chronic…
- Trial name
- VCLBP (NCT06576739)
- Testing
- Spinal Manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Western States
Muscle Weakness
Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness
The goal of this trial was to determine if a mid-thoracic high velocity low amplitude spinal manipulation improves force output in those with unilateral hip adductor weakness.
- Trial name
- NCT06534931
- Testing
- High velocity low amplitude thoracic spine manipulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New England
Healthy Individuals
Comparison of the Effectiveness of Spinal Stabilization Exercises and Chiropractic Spinal Manipulation
It is the study of the effectiveness of spinal stabilization exercises and chiropractic spinal manipulation in healthy individuals.
- Trial name
- NCT04830098
- Testing
- Spinal stabilization exercises, Chiropractic manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Neck Pain
Cervical Spinal Manipulation and Visteral Osteopathy for Mechanical Neck Pain
This study compares two treatment techniques, cervical spinal manipulation (CSM) and visceral osteopathy (VO), in patients with mechanical neck pain (MNP).
- Trial name
- NCT06649903
- Testing
- Chiropractic, Osteopathy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Weightlifting, Breathing
The Effects of Cervical and Thoracic Manipulation Therapy Applied to Weightlifting Athletes
The effects of manipulation therapy on the autonomic nervous system have been examined in the literature and while no sympathetic or parasympathetic changes were found after upper thoracic manipulation, a decrease in sympathetic…
- Conditions
- Weightlifting, Breathing, Breath Tests, Athlete
- Trial name
- NCT06606795
- Testing
- Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Spinal Manipulation
Sensing-glove System in Manual Therapy
The objective of this clinical trial is to assess manual therapists' attitudes towards using a sensing-glove system for measuring spinal manipulation force and to compare the effectiveness of two interventions in enhancing their…
- Trial name
- NCT06432946
- Testing
- Video, Practice session
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières