Clinical trials: Marijuana
Cannabis Use Disorder
Lorcaserin for Cannabis Use Disorder
The primary purpose of this study is to investigate the effect of lorcaserin on reductions in cannabis use and multiple constructs of impulsivity in outpatient treatment-seeking individuals with cannabis use disorder (CUD).
- Trial name
- NCT03637842
- Testing
- Lorcaserin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- New York State Psychiatric Institute
Alcohol Use, Marijuana Use
Motivational Interviewing and Culture for Urban Native American Youth (MICUNAY)
The investigators plan to develop and test a new alcohol and other drug (AOD) intervention for urban AI/AN youth, "Motivational Interviewing and Culture for Urban Native American Youth (MICUNAY)." This intervention integrates…
- Trial name
- MICUNAY (NCT02290938)
- Testing
- MICUNAY, Community Wellness Gathering
- Where
- 2 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- RAND
Spinal Cord Injuries, Spinal Cord Diseases
Vaporized Cannabis and Spinal Cord Injury Pain
This study will demonstrate that vaporized marijuana results in antinociception when compared to placebo in subjects with spinal cord injury.
- Trial name
- NCT01555983
- Testing
- Vaporization of Cannabis
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Barth Wilsey
Cannabis Dependence
Quetiapine Pharmacotherapy for Cannabis Dependence
Despite a benign public perception, marijuana use disorders represent a significant public health problem. The development of safe and effective pharmacotherapies for marijuana dependence is an important unmet public health need.
- Trial name
- QUEST (NCT01697709)
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Cannabis Dependence
An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents
The purpose of this pilot study is to determine the feasibility of conducting a trial of N-Acetylcysteine in cannabis dependent adolescents.
- Trial name
- NAC MJ Pilot (NCT00542750)
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical University of South Carolina
Cannabis Dependence
Study of Long-Acting Injectable Naltrexone to Treat Cannabis Dependence
This is an 8 week, outpatient research study testing the use of long-acting naltrexone (Vivitrol) as a treatment for marijuana dependence.
- Trial name
- NCT02088177
- Testing
- Long-acting injectable naltrexone
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- New York State Psychiatric Institute
Alcohol Drinking, Marijuana
Marijuana's Impact on Alcohol Motivation and Consumption
This laboratory study will employ a repeated measures experimental design to examine the effect of high (7.2% THC) and moderate (3.1% THC) dose of marijuana, relative to placebo, on alcohol craving and on behavioral economic…
- Trial name
- NCT02983773
- Testing
- THC 7.2%, THC 3.1%
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Brown University
Cannabis Use Disorder
Approach Bias Modification for the Treatment of Cannabis Use Disorder
Effective and durable treatments for cannabis use disorder remain elusive. Given the increasing prevalence rates of cannabis use and CUD nationwide, investigation of novel treatments is warranted.
- Trial name
- NCT03629990
- Testing
- Approach Bias Modification (ABM), Psychosocial therapy for cannabis use disorder.
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Medical University of South Carolina
Measuring THC-induced Cognitive Impairment Using a Mobile Application
Developing a Mobile Method to Measure THC-induced Impairment
Marijuana use, for both recreational and therapeutic purposes, is becoming increasingly common as states remove restrictions on use.
- Trial name
- AIS (NCT03804840)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Cannabis Use
Impact of Progesterone on Stress Reactivity and Cannabis Use
This is a research study to find out if a hormone called progesterone affects marijuana users' stress response and marijuana use.
- Trial name
- NCT03729869
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Medical University of South Carolina
Cannabis Use, Adolescent Behavior
Pilot Trial of Contingency Management for Long-Term Cannabis Abstinence
This study is a critically important first-of-its-kind investigation of the potential research utility of using contingency management to examine long-term changes in cannabis use with six months of abstinence.
- Trial name
- NCT03786224
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder, Nicotine Dependence
Bupropion for ADHD in Adolescents With Substance Use Disorder
Attention deficit hyperactivity disorder (ADHD) is one of the most common co-occurring psychiatric disorders (30-50%) in adolescents with substance use disorders (SUD).
- Conditions
- Attention Deficit Hyperactivity Disorder, Nicotine Dependence, Cannabis Use Disorder
- Trial name
- NCT00936299
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Colorado, Denver
Multiple Sclerosis
A Study to Evaluate the Efficacy of Sativex in Relieving Symptoms of Spasticity Due to Multiple Sclerosis
The purpose of this study was to assess the efficacy of Sativex in relieving symptoms of spasticity in multiple sclerosis
- Trial name
- NCT01599234
- Testing
- Sativex
- Where
- United Kingdom
- Volunteers
- 337 people
- Sponsor
- Jazz Pharmaceuticals
Bipolar I Disorder, Bipolar II Disorder
Gabapentin for Bipolar & Cannabis Use Disorders
The proposed 2-week, double-blind, crossover, proof of concept study aims to measure and manipulate core neurochemical (i.e., dysregulated brain GABA/glutamate homeostasis) and neurobehavioral (i.e., elevated impulsivity)…
- Conditions
- Bipolar I Disorder, Bipolar II Disorder, Cannabis Use Disorder, Substance Use Disorders
- Trial name
- NCT03334721
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Medical University of South Carolina
Marijuana Dependence
Buspirone Treatment for Marijuana Dependence
Marijuana is the most commonly used illicit drug, yet few clinical trials have evaluated pharmacotherapy treatments for marijuana dependence.
- Trial name
- NCT00875836
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Medical University of South Carolina
Solid Tumor, Adult
Cannabis Use in Cancer Patients
The goal of this study is to determine the feasibility of a human observational study of orally administered cannabis use among cancer patients.
- Trial name
- NCT03617692
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Colorado, Denver
Cannabis Dependence
Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal
Cannabis dependence is associated with changes in the brain's cannabinoid system. When cannabis dependent individuals try to quit using cannabis, some of them experience problems that make it difficult for them to achieve and…
- Trial name
- NCT01618656
- Testing
- PF-04457845
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Yale University
Pain
A Study of Cannabis Based Medicine Extracts and Placebo in Patients With Pain Due to Spinal Cord Injury
A study to investigate the effects of sublingual cannabis based medicine extracts on neuropathic pain associated with spinal cord injury.
- Trial name
- NCT01606202
- Testing
- GW-1000-02
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- Jazz Pharmaceuticals
Chronic Pain
Reactions of Older Adults Driving After Cannabis Exposure
Objective of the Protocol: The primary aim of the current protocol is to examine whether or not habitual use of medical marijuana affects psychomotor functioning operationalized as driving performance.
- Trial name
- ROADACE (NCT04629716)
- Testing
- Medical Cannabis
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Florida State University
Schizophrenia, Dual Diagnosis
Treatment of Schizophrenia and Comorbid Cannabis Use Disorder: Comparing Clozapine to Treatment-as-Usual
Many individuals with schizophrenia also suffer from marijuana addiction. Clozapine, an atypical antipsychotic medication, may prove useful at preventing drug relapse in schizophrenic individuals who are seeking treatment for…
- Conditions
- Schizophrenia, Dual Diagnosis, Schizoaffective Disorder, Psychotic Disorder
- Trial name
- NCT00498550
- Testing
- Clozapine, Treatment as usual
- Where
- 4 sites in United States
- Volunteers
- 31 people
- Sponsor
- Dartmouth-Hitchcock Medical Center