Clinical trials: Marijuana Abuse
Marijuana Dependence
Effectiveness Study of Dronabinol and BRENDA for the Treatment of Cannabis Withdrawal
This treatment study is targeted specifically for those who want to stop using marijuana. We want to find out if patients who are dependent on marijuana and want to stop using are helped by a combination of the drug dronabinol…
- Trial name
- NCT00480441
- Testing
- Dronabinol, BRENDA therapy
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Marijuana Abuse
The Effect of Prescription Medications in Marijuana Users
A subset of heavy marijuana users have trouble quitting marijuana use and the number of those seeking treatment for problems related to marijuana is increasing.
- Trial name
- NCT00893074
- Testing
- Dronabinol 30mg/day, Dronabinol 60mg/day, Dronabinol 120mg/day
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cigarette Smoking, Marijuana Abuse
Mobile Contingency Management for Marijuana and Tobacco Cessation
The purpose of this pilot project is to pilot-test a combined cannabis and smoking cessation treatment. The intervention combines mobile technology with behavioral strategies, counseling, and medications.
- Trial name
- NCT02869451
- Testing
- bupropion, transdermal nicotine patch, Nicotine polacrilex
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Cannabis, Cannabis Use
Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)
Nearly 20 million Americans report use of cannabis in the past month, and heavy cannabis use has increased by nearly 60% in the U.S. since 2007.
- Trial name
- FOCUS (NCT04567238)
- Testing
- Mobile contingency management
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Obsessive-Compulsive Disorder
Effects of Marijuana on Symptoms of OCD
The purpose of this pilot research study is to test whether certain components of the marijuana plant, known as "cannabinoids", may help to reduce symptoms in patients with OCD.
- Trial name
- ECOS (NCT03274440)
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Smoking, Cannabis
Imaging the Neurochemistry of Drug Addiction With PET
The investigators' project has two overarching goals. 1) The investigators will use newly developed positron emission tomography (PET) technology to investigate the dopaminergic neurochemistry of drugs of abuse including…
- Trial name
- NCT02817698
- Testing
- cannabis
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Yale University
Cannabis, Nicotine
Behavioral Pharmacology of Cannabis and Nicotine
This study will evaluate the individual and interactive pharmacokinetic and pharmacodynamic effects of smoked cannabis and nicotine.
- Trial name
- NCT04124432
- Testing
- Cannabis, Nicotine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pain
Opioid and Cannabinoid Pharmacokinetic Interactions
We are conducting a study to assess whether smoking marijuana affects the safety of prescribed opioids in patients treated for chronic pain.
- Trial name
- NCT00308555
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Francisco
Bipolar Disorder, Cannabis-Related Disorder
Efficacy Study of Quetiapine Plus Topiramate for Reducing Cannabis Consumption and Bipolar Mania
The objectives of this study are to determine whether this treatment may be useful for reducing cannabis consumption; reducing symptoms of bipolar mania; and weight mitigation therapy for individuals on psychopharmacotherapy.
- Trial name
- NCT00393978
- Testing
- Quetiapine and Topiramate
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Cincinnati
Cannabis Use Disorder
N-Acetylcysteine for Youth Cannabis Use Disorder
This is a 12-week randomized, placebo-controlled trial of N-acetylcysteine for cannabis use disorder (CUD) in youth (N=192). Participants will be randomized to double-blind NAC or PBO, yielding two equally-allocated treatment…
- Trial name
- NCT03055377
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Medical University of South Carolina
Pain Threshold, Mood
Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers
The following study is designed to determine the analgesic efficacy of smoked marijuana (0, 1.98, and 3.56% THC) and oral THC (0, 10, and 20 mg) in the Cold-Pressor Test (CPT), a laboratory model of pain which has predictive…
- Trial name
- NCT00743119
- Testing
- Inactive marijuana (0% THC), Low dose Dronabinol, High dose Dronabinol
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Cannabis Dependence, Cannabis Withdrawal
Gabapentin Treatment of Cannabis Dependence
This is a clinical study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.
- Conditions
- Cannabis Dependence, Cannabis Withdrawal, Cognitive Deficits
- Trial name
- NCT00974376
- Testing
- gabapentin 1200mg/day, Manual-guided behavioral counseling
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The Scripps Research Institute
Substance Use Disorders
Behavioral Treatment of Adolescent Substance Use
This study will continue research designed to improve treatment outcomes for adolescent substance use disorders by integrating neuroscience- and behaviorally-based treatments.
- Trial name
- SMART (NCT02063984)
- Testing
- Intensive Outpatient Treatment (IOP) + Contingency Management (CM), Working Memory Training
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Marijuana Abuse and Dependence
Development and Efficacy Test of Computerized Treatment for Marijuana Dependence
More US residents are dependent on marijuana than on any other illicit drug, and the number enrolled in treatment for marijuana continues to increase such that it is now comparable to that for cocaine and heroin.
- Trial name
- NCT00594659
- Testing
- Psychotherapy, Computerized Psychotherapy, Motivational enhancement therapy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Marijuana Dependence
Effect of Baclofen on Marijuana Withdrawal and Relapse
The purpose of this study is to determine if baclofen dose-dependently decreases marijuana's direct effects and symptoms of marijuana withdrawal and thus decreases marijuana relapse.
- Trial name
- NCT00373295
- Testing
- Baclofen, Marijuana
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Alcohol Drinking, Marijuana
Marijuana's Impact on Alcohol Motivation and Consumption
This laboratory study will employ a repeated measures experimental design to examine the effect of high (7.2% THC) and moderate (3.1% THC) dose of marijuana, relative to placebo, on alcohol craving and on behavioral economic…
- Trial name
- NCT02983773
- Testing
- THC 7.2%, THC 3.1%
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Brown University
Risk Reduction Behavior, Health Behavior
Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents
This research is studying behaviors that young people engage in that may place them at risk for contracting a sexually transmitted disease like HIV/AIDS, and what kind of educational program works best to reduce these risky…
- Conditions
- Risk Reduction Behavior, Health Behavior, Sexual Behavior, Adolescent Behavior
- Trial name
- MARS (NCT01170260)
- Testing
- INFORMATION-ONLY SEXUAL RISK REDUCTION (INFO-ONLY), SEXUAL PLUS ALCOHOL RISK REDUCTION (SRRI+ETOH), SEXUAL + ALCOHOL + MARIJUANA RISK REDUCTION
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Marijuana Abuse, Attention Deficit Disorder With Hyperactivity
Atomoxetine Treatment for ADHD and Marijuana Dependence
The aim of the study is to determine if atomoxetine treatment combined with motivational enhancement therapy is effective in reducing marijuana use in adult individuals with attention-deficit hyperactivity disorder and marijuana…
- Trial name
- NCT00360269
- Testing
- Atomoxetine, Motivational enhancement therapy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Medical University of South Carolina
Medical Abortion, Pain
Cannabinoids for Pain Control During Medical Abortion
The objective of this study is to determine if a synthetic cannabis derivative, dronabinol, in addition to ibuprofen, decreases maximum pain scores compared to ibuprofen and placebo in women undergoing medical abortion.
- Trial name
- NCT03604341
- Testing
- Dronabinol 5mg Cap
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Oregon Health and Science University
Spinal Cord Injuries, Spinal Cord Diseases
Vaporized Cannabis and Spinal Cord Injury Pain
This study will demonstrate that vaporized marijuana results in antinociception when compared to placebo in subjects with spinal cord injury.
- Trial name
- NCT01555983
- Testing
- Vaporization of Cannabis
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Barth Wilsey