Clinical trials: Marijuana Dependence
Cannabis Dependence
An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents
The purpose of this pilot study is to determine the feasibility of conducting a trial of N-Acetylcysteine in cannabis dependent adolescents.
- Trial name
- NAC MJ Pilot (NCT00542750)
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical University of South Carolina
Cannabis Dependence
Study of Long-Acting Injectable Naltrexone to Treat Cannabis Dependence
This is an 8 week, outpatient research study testing the use of long-acting naltrexone (Vivitrol) as a treatment for marijuana dependence.
- Trial name
- NCT02088177
- Testing
- Long-acting injectable naltrexone
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- New York State Psychiatric Institute
Attention Deficit Hyperactivity Disorder, Nicotine Dependence
Bupropion for ADHD in Adolescents With Substance Use Disorder
Attention deficit hyperactivity disorder (ADHD) is one of the most common co-occurring psychiatric disorders (30-50%) in adolescents with substance use disorders (SUD).
- Conditions
- Attention Deficit Hyperactivity Disorder, Nicotine Dependence, Cannabis Use Disorder
- Trial name
- NCT00936299
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Colorado, Denver
Marijuana Dependence
Buspirone Treatment for Marijuana Dependence
Marijuana is the most commonly used illicit drug, yet few clinical trials have evaluated pharmacotherapy treatments for marijuana dependence.
- Trial name
- NCT00875836
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Medical University of South Carolina
Cannabis Dependence
Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal
Cannabis dependence is associated with changes in the brain's cannabinoid system. When cannabis dependent individuals try to quit using cannabis, some of them experience problems that make it difficult for them to achieve and…
- Trial name
- NCT01618656
- Testing
- PF-04457845
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Yale University
Cannabis Dependence, Nicotine Dependence
Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence
The investigators are conducting a Stage 1 pilot feasibility study at McLean Hospital to develop and refine a Cognitive Behavioral Therapy (CBT) intervention.
- Trial name
- CBT-MJ-NIC (NCT01292642)
- Testing
- Cognitive Behavioral Therapy, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mclean Hospital
Marijuana Dependence
Baclofen Effects on Marijuana Dependence
Studies show that certain reminders of drug use such as the sight of someone using marijuana, pictures of blunts, particular moments throughout the day, prompt marijuana users to smoke marijuana.
- Trial name
- NCT02011516
- Testing
- Baclofen, Psychosocial
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cannabis Dependence
Fixed or Self-Titrated Dosages of Sativex on Cannabis Users
The purpose of this study is to to demonstrate the feasibility and tolerability of the use of Sativex in cannabis dependent individuals and to assess the effects of fixed or self titrated dosages of SATIVEX®…
- Trial name
- NCT01748799
- Testing
- Sativex
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre for Addiction and Mental Health
Cannabis Dependence
Sativex and Behavioral-relapse Prevention Strategy in Cannabis Dependence
The purpose of this study is assess Sativex as a treatment for Cannabis dependence. Initially a pilot study will be conducted in five subjects seeking treatment for cannabis dependence to ensure that our planned self-titration…
- Trial name
- NCT01747850
- Testing
- Motivational Enhancement/Cognitive Behavioral Therapy, Sativex
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Centre for Addiction and Mental Health
Cannabis, Marijuana Abuse
Dronabinol Interactions With Cognitive Enhancing Drug in Humans
Marijuana use is a major problem among veterans and non-veterans. A patient's use of marijuana while engaged in psychotherapy treatment may affect their memory and, therefore, limit their ability to benefit from treatment.
- Trial name
- NCT00842985
- Testing
- drug condition
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Yale University
Marijuana Dependence
Vaping THC From Electronic Cigarettes
This study aims to understand THC pharmacology and the safety of cannabis vaping, including the pharmacology and safety of co-administration of nicotine and THC.
- Trial name
- V-PAX (NCT02955329)
- Testing
- Nicotine, Cannabis, PAX Loose Leaf Vaporizer
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cannabis Dependence
Study of Quetiapine Treatment for Cannabis Dependence
Marijuana is the most commonly used illicit drug in the United States. However, the treatment options for cannabis dependence are limited; notably, no effective pharmacotherapy has been developed.
- Trial name
- STUC (NCT00954681)
- Testing
- quetiapine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York State Psychiatric Institute
Marijuana Abuse and Dependence
Development and Efficacy Test of Computerized Treatment for Marijuana Dependence
More US residents are dependent on marijuana than on any other illicit drug, and the number enrolled in treatment for marijuana continues to increase such that it is now comparable to that for cocaine and heroin.
- Trial name
- NCT00594659
- Testing
- Psychotherapy, Computerized Psychotherapy, Motivational enhancement therapy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cannabis Dependence
Facilitating the Behavioral Treatment of Cannabis Use Disorder
Cannabis use disorders remain a significant public health problem. The pharmacological facilitation of behavioral treatment represents a promising strategy for addressing disordered cannabis use.
- Trial name
- NCT02946489
- Testing
- CI-581a
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- New York State Psychiatric Institute
Cannabis Dependence
Treatment for Cannabis Withdrawal and Dependence
Cannabis is the most widely used illicit drug in the United States, and worldwide, with 1 in 10 users estimated to meet diagnostic criteria for cannabis dependence.
- Trial name
- NCT01611948
- Testing
- Aprepitant, Manual-guided behavioral counseling
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Scripps Research Institute
Cannabis Dependence, Tobacco Dependence
Varenicline for Co-occurring Cannabis and Tobacco Use
Pilot, eight week, open-label, within-subject cross over trial of four weeks of standard clinical care (SCC) in an outpatient substance use disorder treatment program and four weeks of SCC and varenicline among current and former…
- Trial name
- NCT04595318
- Testing
- Standard clinical care first, followed by standard clinical care and varenicline, Standard clinical care and varenicline first, followed by standard clinical care
- Volunteers
- 7 people
- Sponsor
- Albert Einstein College of Medicine
Cannabis Dependence, Cannabis Withdrawal
Gabapentin Treatment of Cannabis Dependence
This is a clinical study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.
- Conditions
- Cannabis Dependence, Cannabis Withdrawal, Cognitive Deficits
- Trial name
- NCT00974376
- Testing
- gabapentin 1200mg/day, Manual-guided behavioral counseling
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The Scripps Research Institute
Depressive Disorder, Major, Cannabis Abuse
Effectiveness of Fluoxetine in Young People for the Treatment of Major Depression and Marijuana Dependence
Adolescents who are diagnosed with major depressive disorder are often also diagnosed with marijuana dependence. Fluoxetine is an antidepressant medication currently used to treat young people who are diagnosed with major…
- Trial name
- CADY (NCT00149643)
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Pittsburgh
Cannabis Dependence
Gabapentin Treatment of Cannabis Dependence
This is a study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.
- Trial name
- NCT00395044
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Scripps Research Institute
Cannabis Dependence, Alcohol Dependence
Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence
The primary aim of the supplemental study is to provide POC testing of aprepitant as a treatment for comorbid alcohol and cannabis dependence.
- Conditions
- Cannabis Dependence, Alcohol Dependence, Cannabis Use Disorder, Alcohol Use Disorder
- Trial name
- NCT02210195
- Testing
- aprepitant, Manual-guided behavioral counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Scripps Research Institute