Clinical trials: Marijuana Use, open to volunteers
Perinatal, Cannabis Use
Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum
Using both tobacco and cannabis during pregnancy is more common in minoritized groups and can make quitting smoking in pregnancy and remaining smoke free postpartum difficult.
- Conditions
- Perinatal, Cannabis Use, Tobacco Use, Smoking Cessation
- Trial name
- PICTURe (NCT07489443)
- Testing
- Perinatal smoking cessation treatment and maintenance sessions
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Schizophrenia, Cannabis Dependence
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
The aim of the present study is to assess the availability of cannabinoid receptors (CB1R) in the human brain. CB1R are present in everyone's brain, regardless of whether or not someone has used cannabis.
- Conditions
- Schizophrenia, Cannabis Dependence, Prodromal for Psychotic Illness, Family History of Alcoholism
- Trial name
- NCT01730781
- Testing
- [11-C]OMAR
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
Cannabis Smoking, Oxidative Stress
Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response
This study plans to evaluate the effects of chronic cannabis smoking on lung health by evaluating its effects on pulmonary health, lung physiology and alveolar macrophage function.
- Trial name
- NCT02480283
- Testing
- Bronchoscopy, Chest X-ray, Venipuncture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sleep
Cannabis Association With Sleep Study
The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.
- Trial name
- CaSS (NCT06982950)
- Testing
- Manipulation of Sleep Duration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cannabis Use, Marijuana Usage
Impact of Cannabis Use During Third Molar Surgery
This study is for people scheduled to have their wisdom teeth (third molars) removed and are going to receive drug through an IV to put them to sleep.
- Conditions
- Cannabis Use, Marijuana Usage, Sedation and Analgesia, Wisdom Tooth
- Trial name
- NCT07423195
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- University of Michigan
Cannabis Intoxication
Effects of Various Cannabis Strains on Perceptual, Subjective and Objective Use Outcomes
This study will evaluate the subjective and behavioral effects of cannabis products labeled as indica, sativa, or generic.
- Trial name
- NCT07214155
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Alcohol and Tobacco/Cannabis Use
FASD Prevention R33
This R33 application proposes to adapt and test an evidence-based behavioral intervention to decrease polysubstance use (i.e., alcohol and tobacco/cannabis) during pregnancy and lactation and prevent adverse clinical outcomes…
- Trial name
- R33 (NCT07828275)
- Testing
- Intervention, Usual Care
- Where
- South Africa
- Volunteers
- 184 people
- Sponsor
- Philadelphia College of Osteopathic Medicine
Substance Use Behavior, Cannabis Intoxication
Substance Use and Media Preferences
The goal of this randomized clinical trial is to learn how alcohol use, cannabis use, and using both substances affect whether and how quickly people stop a video being shown to a woman.
- Conditions
- Substance Use Behavior, Cannabis Intoxication, Alcohol Intoxication
- Trial name
- NCT07922239
- Testing
- Alcohol beverage, Cannabis (smoked flower), Simultaneous Alcohol and Cannabis
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cannabis Use, Alcohol Use, Unspecified
Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)
This is a randomized, parallel-group study designed to explore the differences between cannabis intoxication, alcohol intoxication and co-intoxication involving both alcohol and cannabis, utilizing electroencephalography (EEG) as…
- Trial name
- NCT06259916
- Testing
- Alcohol, Cannabis
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Cannabis Use, Major Depressive Disorder
Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression
The prevalence of major depressive disorder (MDD) is ~5.0%, and rates of co-occurring SUDs in these patients approach 40-50%. Specifically, rates of co-morbid cannabis use disorder (CUD) in patients with MDD are elevated 2-3 fold…
- Conditions
- Cannabis Use, Major Depressive Disorder, Cognitive Impairment
- Trial name
- NCT04935619
- Testing
- Contingency Reinforcement, Non-Contingency Reinforcement
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Centre for Addiction and Mental Health
Cannabis Use, Depression
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
The goal of this study is to investigate the effects of cannabis on brain function among adolescents with depression.
- Trial name
- Cann-Teen (NCT06941298)
- Testing
- Neuroimaging Investigation
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cannabis Use Disorder
Tirzepatide for the Treatment of Cannabis Use Disorder
This is a pilot randomized cross-over trial to examine the effects of tirzepatide on cue-reactivity among individuals with cannabis use disorder.
- Trial name
- NCT07265752
- Testing
- Tirzepatide
- Volunteers
- 6 people
- Sponsor
- Brigham and Women's Hospital
Schizophrenia, Cannabis-Induced Disorder
Examining tDCS Effect on Cannabis Use Disorder in Patients With Schizophrenia
Cannabis use disorder is a frequent comorbidity of schizophrenia, associated with increased symptoms and less adherence to therapy.
- Trial name
- CANNAPSYSTIM (NCT04871048)
- Testing
- Transcranial direct current stimulation (tDCS) active, Transcranial direct current stimulation (tDCS) non active
- Where
- 8 sites in France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cannabis Use, Cannabis Use Disorder
Transcranial Magnetic Stimulation for Adolescents and Young Adults With Cannabis Use Disorder
This pilot study will investigate the potential of repetitive transcranial magnetic stimulation (rTMS) to strengthen a neural circuit critical for maintaining abstinence in adolescents and youth with cannabis use disorder (CUD).
- Trial name
- NCT07634835
- Testing
- Magstim SuperRapid2
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Minnesota
Posttraumatic Stress Disorder, Cannabis Use Disorder
Mitigating PTSD-CUD After Sexual Assault
683,000 women are sexually assaulted annually in the United States, half of whom develop chronic posttraumatic stress disorder (PTSD) and thus have markedly increased risk for cannabis use disorder (CUD).
- Trial name
- RISE-C (NCT05989841)
- Testing
- RISE Guide, Relaxation Control
- Where
- 6 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Nevada, Las Vegas
Eating Disorders, Cannabis Use
A Brief Cannabis Use Psychoeducation Intervention for Eating Disorder Patients
The goal of this clinical trial is to learn if providing eating disorder patients with education about the consequences of cannabis (marijuana) use on mental health, gastrointestinal symptoms, eating disorder symptoms, and eating…
- Trial name
- NCT07387965
- Testing
- Psychoeducation about risks of cannabis use
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Depression, Cannabis Use Disorder
The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV
To elucidate mechanisms of substance use disorders (SUD) and comorbid mental illnesses in people living with HIV (PLWH), the study team seeks to investigate reward and pain circuitry in cannabis use and depression comorbidity…
- Conditions
- Depression, Cannabis Use Disorder, HIV
- Trial name
- NCT05453513
- Testing
- MRI Study
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Miami
Cannabis Use, Cancer
Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)
Through partnership with Ontracka, the HealthPartners Institute Cancer Research Center created a secure and compliant app-based technology with the ability to seamlessly collect patient-level data on symptoms, cannabis use…
- Trial name
- CURIOUS (NCT07227324)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Cannabis Use, Stress
Perceptual Influences From Smoking Cannabis: an Experimental Study
The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognition, perception including the experience of temperature and pain, and…
- Trial name
- PISCES (NCT06588582)
- Testing
- Water Temperature Variation - WW, Water Temperature Variation - CW
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Cancer, Epilepsy
Real World Evidence on the Use of Medical Cannabis in Pediatrics
CAN-RWE is an observational study that is following 500 children who have authorizations for medical cannabis for two years from across Canada.
- Conditions
- Cancer, Epilepsy, Neurodevelopmental Disorders
- Trial name
- CAN-RWE (NCT05863910)
- Testing
- Medical Cannabis
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Manitoba