Clinical trials: Marijuana Use, active
Cannabis Use, Substance Use Disorder (SUD)
Research Investigating Drug Effects-2 (RiDE-2)
The purpose of this study is to better understand how people's mood, behavior, and brains respond to different recreational drugs.
- Conditions
- Cannabis Use, Substance Use Disorder (SUD), Healthy
- Trial name
- RiDE-2 (NCT06758596)
- Testing
- THC
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Methamphetamine Induced Psychosis, Cannabis Use
Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Use
This prospective cohort study aims to investigate factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP) with and without lifetime cannabis use (LCU).
- Trial name
- NCT07459270
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Insomnia
Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use
This study will compare the efficacy of telemedicine-delivered cognitive behavioral therapy for insomnia tailored for people using cannabis for sleep (CBTi-CB-TM) to telemedicine-delivered sleep hygiene education (SHE-TM) on…
- Trial name
- NCT05814822
- Testing
- Cognitive Behavioral Therapy for insomnia (CBTi-CB-TM), Sleep Hygiene Education (SHE-TM)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Cannabis Use, Cannabis Intoxication
Study of an Oral Fluid Testing Approach
The purpose of this study is to identify and evaluate oral fluid testing as a biologic measure of cannabis use days that can be assessed remotely.
- Conditions
- Cannabis Use, Cannabis Intoxication, Cannabis Use Disorder
- Trial name
- SOFTA (NCT06891235)
- Testing
- Biologic testing for THC
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Chronic Pain Patients, Medical Cannabis Users
Medical Cannabis and Behavior
This study will assess cognition, neural function, and drug exposure in chronic pain patients who have been prescribed medical cannabis and will differentiate outcomes based on use of specific CBD-dominant versus THC-dominant…
- Trial name
- NCT06808048
- Testing
- Cognitive testing, Task-based fMRI measure of face-name and verbal learning
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Minnesota
Cannabis Intoxication
Effects of Various Cannabis Strains on Perceptual, Subjective and Objective Use Outcomes
This study will evaluate the subjective and behavioral effects of cannabis products labeled as indica, sativa, or generic.
- Trial name
- NCT07214155
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cannabis Use
Cannabis Use Patterns Among Young Adults and Associations With Social and Health Outcomes.
The purpose of this study is to identify and characterize patterns of non-therapeutic cannabis consumption and their variation in time in regular/daily users aged 18-24 years using a multi-factor approach (frequency of use…
- Trial name
- TRICCHOME (NCT07063589)
- Testing
- Mobile application
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cannabis Use Disorder
A Brief Intervention for Cannabis Use
The purpose of this study is to compare two brief interventions targeting potentially problematic cannabis use in emerging adults (ages 18-25). Brief interventions are two 40-50 minute sessions separated by 1 week.
- Trial name
- Bloom (NCT06395389)
- Testing
- Health Education (HealthEdu), Bloom
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Medical University of South Carolina
Cannabis Use Disorder, Moderate, Cannabis Use Disorder, Severe
Tirzepatide in the Treatment of Cannabis Use Disorder
Cannabis is the most commonly used psychoactive substance in Canada. A sub-group of cannabis users develop Cannabis Use Disorder (CUD).
- Trial name
- NCT07671248
- Testing
- Tirzepatide
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McMaster University
PTSD, Post Traumatic Stress Disorder
Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery
The overall strategy is to recruit veterans with PTSD who report minimal current cannabis use but are interested in or considering therapeutic cannabis to manage mental health symptoms (anxiety, depression, PTSD and/or…
- Conditions
- PTSD, Post Traumatic Stress Disorder, Suicide, Cannabis Use
- Trial name
- CAPER (NCT06222268)
- Testing
- Cannabidiol (CBD) only, Delta-9-tetrahydrocannabinol (THC) only, THC:CBD 1:1
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Leslie Lundahl
Medical Cannabis
Evaluation of Interprofessional Relations Between Primary Care and Hospital Centers in the Experimentation of Medical Cannabis in France Carried Out by the ANSM (ECIPCanna)
An observational study to explore inter-professional relations and perceptions around the experimentation of medical cannabis, conducted by the French National Agency for Safety and Health.
- Trial name
- ECIPCanna (NCT06597097)
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Brest
Psychosis, Cannabis Use
Probing the Cannabinoid System in Individuals With a Family History of Psychosis
The overall purpose of this study is to determine whether a family history of psychosis is associated with an altered cannabinoid system.
- Conditions
- Psychosis, Cannabis Use, THC, Marijuana
- Trial name
- NCT02102113
- Testing
- Very Low Dose THC, Low Dose THC
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Yale University
Depression - Major Depressive Disorder, Cannabis Use Disorder
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
The purpose of this study is to examine the feasibility, acceptability, and preliminary efficacy of a digital intervention for co-occurring cannabis use and depression.
- Conditions
- Depression - Major Depressive Disorder, Cannabis Use Disorder, Mental Disorder
- Trial name
- NCT06878859
- Testing
- Amplification of Positivity - Cannabis Use (AMP-C)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Psychotic Disorders, Cannabis Use Disorder
RCT Comparing Avatar Intervention to Supportive Intervention to Reduce Cannabis Use in Patients With Psychotic Disorders
The goal of this clinical trial is to conduct a single-blind randomized controlled trial to verify whether the Avatar Intervention has greater efficacy over supportive intervention to reduce cannabis use in patients with…
- Conditions
- Psychotic Disorders, Cannabis Use Disorder, Mental Health Disorder
- Trial name
- AC2 (NCT05704582)
- Testing
- Avatar Intervention, Addiction supportive intervention
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Cannabis Use Disorder
Endocannabinoids in Reward
This study will examine sex differences in the effects of cannabis in people that regularly use it. Men and women that use cannabis at least 4 days a week will participate in a study involving 3 in-person visits.
- Trial name
- NCT07815691
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Medical University of South Carolina
Substance Use, Binge Drinking
Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care
This study evaluates whether completing a short screening questionnaire about health behaviours in the waiting room before a primary care consultation decreases excessive substance use in young people aged 14 to 24 years.
- Conditions
- Substance Use, Binge Drinking, Cannabis Use, Adolescent Behavior
- Trial name
- YP-HEALTH (NCT04146714)
- Testing
- Substance use questionnaire, Physical activity questionnaire
- Where
- Switzerland
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Prof. Dagmar M. Haller
Child Development, Cannabis Use
Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development
The goal of this study is to determine if providing a nutritional supplement, phosphatidylcholine, to pregnant women who have used cannabis products during the current pregnancy improves the offspring\'s brain-related…
- Trial name
- NCT06379971
- Testing
- Choline
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Schizophrenia and Other Psychotic Disorders, Cannabis Use Disorder
SV2 PET Imaging With [11C]APP311
The aim of this study is to evaluate a new SV2A tracer, [11C]APP311, in healthy aging and neuropsychiatric disorders including psychotic disorders and cannabis use disorders.
- Conditions
- Schizophrenia and Other Psychotic Disorders, Cannabis Use Disorder, Healthy
- Trial name
- SV2 (NCT03995121)
- Testing
- [11C]APP311
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Yale University
Opioid Use Disorders, Cannabis Use
Cannabis and Opioid Use Disorder, Study 2
This inpatient study enrolls healthy individuals who have opioid use disorder. Participants live at the University of Kentucky Hospital for approx. 6 weeks.
- Trial name
- NCT07661446
- Testing
- Inhaled Cannabis, Intranasal Opioid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Kentucky
Perinatal, Cannabis Use
Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum
Using both tobacco and cannabis during pregnancy is more common in minoritized groups and can make quitting smoking in pregnancy and remaining smoke free postpartum difficult.
- Conditions
- Perinatal, Cannabis Use, Tobacco Use, Smoking Cessation
- Trial name
- PICTURe (NCT07489443)
- Testing
- Perinatal smoking cessation treatment and maintenance sessions
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh