Clinical trials: Mask
Dry Eye Disease
Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops
The primary objective is to evaluate the tolerability and efficacy of CWT-f-002 lubricant eye drops in the treatment of the signs and symptoms of dry eye disease.
- Trial name
- NCT05660681
- Testing
- glycerin 0.7%/PEG 400 0.3%, polyethylene glycol 400 0.4%/propylene glycol 0.3%
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Calm Water Therapeutics LLC
Anesthesia
Different Dose of Esketamine Inhibiting Response to Laryngeal Mask Airway Insertion
Objective To prospectively determine the median effective dose (ED50) of propofol for inhibiting a response to laryngeal mask airway (LMA) insertion when combined with different doses of esketamine in female patients.
- Trial name
- NCT06370130
- Testing
- Esketamine 0.2mg/kg, Esketamine 0.3mg/kg
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Aerospace Center Hospital
Intubation
Comparison of Two-hand Mask Ventilation Technique: Standard V-E Versus Reversal V-E Technique
This study hypothesizes that a novel reversal V-E ventilation technique will retain its high efficiency as that of standard V-E technique and will be easier to use.
- Trial name
- NCT03170037
- Testing
- Standard V-E ventilation technique, Reversal V-E ventilation technique
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Vanderbilt University Medical Center
Healthy Subjects
A Study to Explore the Physiological Impact of AIR+ KN95 Masks on Children
The primary objective is to evaluate the physiological impact of AIR+ KN95 Masks on end-tidal carbon dioxide (ETCO2) of children aged 7 to 14 years of age.
- Trial name
- NCT07037381
- Testing
- KN95 mask
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Innosparks Pte Ltd.
Angle-closure Glaucoma
Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG)
The purpose of this study is to demonstrate that the Intraocular Pressure (IOP) lowering efficacy of Travoprost Ophthalmic Solution 0.004% is superior to that of Pilocarpine 1% in patients with chronic angle-closure glaucoma…
- Trial name
- NCT00762645
- Testing
- Travoprost 0.004% (Travatan), Pilocarpine 1%
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Glaucoma, Open Angle
Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma
Low-pressure (normal tension) glaucoma is a type of open-angle glaucoma resulting in damage to the optic nerve and abnormalities of the visual field.
- Trial name
- NCT00317577
- Testing
- brimonidine, timolol
- Where
- 12 sites in United States
- Volunteers
- 160 people
- Sponsor
- Chicago Center for Vision Research
Persistent Epithelial Defect
A Study to Investigate the Safety and Clinical Effect of Nexagon® to Treat Persistent Epithelial Defects
The purpose of this study is to evaluate the efficacy and safety of Nexagon® in subjects with Persistent Epithelial Defects (PED) originally caused by chemical burns.
- Trial name
- NCT00821561
- Testing
- Nexagon®, Nexagon® vehicle
- Volunteers
- 90 people
- Sponsor
- OcuNexus Therapeutics, Inc.
Stress Urinary Incontinence
Bulking Agents for the Treatment of Stress Urinary Incontinence in Females
The primary purpose of this study is to demonstrate the safety and effectiveness of Bulkamid® in the treatment of stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (ISD) in adult women who have SUI or stress…
- Trial name
- NCT00629083
- Testing
- Bulkamid, Contigen
- Where
- 34 sites in United States, Canada and 1 more
- Volunteers
- 345 people
- Sponsor
- Contura
Laryngeal Masks, Minors
Comparison of Weight-based Versus External Ear-size Based Technique for Selection of Laryngeal Mask Airway in Pediatric Surgical Patients.
Laryngeal Mask Airway (LMA) is widely used in pediatric surgical patients. The manufacturer recommends the size of LMA to be used in children should be based on actual body weight but this method has several limitations.
- Conditions
- Laryngeal Masks, Minors, Child, Pediatrics
- Trial name
- NCT03931122
- Testing
- Ear Size Based Method (Ambu® AuraOnce™ Laryngeal Mask Airway)
- Where
- Pakistan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Non-Proliferative Diabetic Retinopathy
A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy
A Phase 2, Randomized, Double-masked, Placebo-controlled Multicenter Clinical Trial Designed to Evaluate the Safety and Efficacy of Luminate in Inducing PVD in Subjects with Non-Proliferative Diabetic Retinopathy.
- Trial name
- NCT02435862
- Testing
- 1.0mg Luminate®, 2.0mg Luminate®, 3.0mg Luminate®
- Where
- 12 sites in United States
- Volunteers
- 105 people
- Sponsor
- Allegro Ophthalmics, LLC
Myopia
Clinical Evaluation on Using Personal Face Masks With Spectacles Versus Contact Lenses
The aim of this study was to explore satisfaction with vision correction and ease of use of PFM (Personal Face Masks) in a group of spectacle wearers who were randomised to continue wearing spectacles or be fitted with daily…
- Trial name
- NCT04658797
- Testing
- somofilcon A Daily Disposable Contact Lens, Single Vision Spectacle for Vision Correction, Personal Facemask
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Age-Related Macular Degeneration
Study to Evaluate Sub-retinal Transplantation of Retinal Pigmented Epithelial Cells in Patients With Dry AMD
To evaluate the safety of 3 regimens of short-term, low-dose systemic IMT as rejection prophylaxis prior to and/or following transplant of MA09-hRPE cells.
- Trial name
- PORTRAY (NCT02563782)
- Testing
- Sub-retinal transplantation of MA09-hRPE cells, tacrolimus and mycophenolate mofetil
- Where
- United States
- Sponsor
- Astellas Institute for Regenerative Medicine
Laryngeal Mask Airway
Usage of LMA Protector on Patients Who Undergo Laparoscopic Surgery
LMA Protector is a recently developed second generation laryngeal mask several kinds of different laryngeal masks were used for the airway management during laparoscopic surgeries.
- Trial name
- LMAP-LS (NCT03453138)
- Testing
- LMA Protector, Tracheal Intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people
- Sponsor
- Derince Training and Research Hospital
Difficult Intubation, Obesity
Evaluation of Difficult Airway With Ultrasonography
As a result of anatomical and physiological changes in obese patients, airway management can be challenging. Ultrasound measurement of neck anterior soft tissues combined with recommended predictive tests may increase the ability…
- Trial name
- NCT04289597
- Testing
- Distance between hyoid bone-skin (DSHB), Vocal cord anterior commissura-skin distance (DSAC), minimum distance of the trachea to the skin at the level of suprasternal notch
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Mydriasis, Dilation
Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)
The objectives of this study are: To evaluate the efficacy of Nyxol to expedite the reversal of pharmacologically-induced mydriasis across multiple mydriatic agents with an emphasis on phenylephrine To evaluate the efficacy of…
- Trial name
- MIRA-3 (NCT05134974)
- Testing
- Phentolamine Ophthalmic Solution 0.75%, Phentolamine Ophthalmic Solution Vehicle
- Where
- 15 sites in United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Opus Genetics, Inc
Acute Respiratory Infections (ARIs), Influenza
Effect of Surgical Masks in Preventing Acute Respiratory Infections
The goal of this clinical trial is to evaluate the efficacy of surgical masks in preventing acute respiratory tract infections. The main question it aims to answer is: Does wearing a mask prevent you from getting acute…
- Conditions
- Acute Respiratory Infections (ARIs), Influenza, COVID - 19
- Trial name
- NCT07739446
- Testing
- Surgical masks
- Where
- Japan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Chiba University
Wet Age-related Macular Degeneration
Study of SCB-420 in Subjects With Neovascular Age-related Macular Degeneration
This is a Phase 1, randomized, double-masked, multicenter, parallel-assignment, pilot study to evaluate the safety, tolerability, initial clinical effectiveness, pharmacokinetics (PK), and immunogenicity of SCB-420 as compared…
- Trial name
- NCT04919096
- Testing
- SCB-420, Aflibercept
- Sponsor
- Clover Biopharmaceuticals AUS Pty
Anesthesia, Child
Evaluation of the Pediatric Igel Airway in 250 Children
Once a child has been anaesthetised and is fully asleep, a special airway tube called a laryngeal mask is often inserted into their mouth to help with their breathing. This tube is removed just before the child wakes up.
- Conditions
- Anesthesia, Child, Infant
- Trial name
- NCT00969189
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Primary Open-angle Glaucoma
Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract Surgery
Evaluate the safety and efficacy of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 using the G2-M-IS injector system in conjunction with cataract surgery vs.
- Trial name
- NCT01461291
- Testing
- iStent inject, Cataract surgery
- Where
- United States
- Volunteers
- 505 people
- Sponsor
- Glaukos Corporation
ENT Tumor
Comparison of HFNO and FMV on Desaturations During Panendoscopy Under General Anesthesia
Panendoscopy is a common procedure that requires deep and short anesthesia. The main challenge is the sharing of the airway between the anesthesia team and the surgical team.
- Trial name
- NCT05593718
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
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